Measurements of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). I. Chemical analysis and biological properties of PEG 400

Gastroenterology

Volumn 73, Issue 2, 1977, Pages 241-246

  Chadwick, V S ^a   Phillips, S F ^a   Hoffmann, A F ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROGOL;

DIGESTIVE SYSTEM; INTESTINE; PERMEABILITY;

EID: 0017377913     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0016-5085(19)32196-1     Document Type: Article

References (17)

1. Fordtran J.S. Rector F.C. Ewton M.F. Permeability characteristics of the human small intestine J Clin Invest 44 1965 1935 1944
2. Fordtran J.S. Rector F.C. Locklear T.W. Water and solute movement in the small intestine of patients with sprue J Clin Invest 46 1967 287 298
3. Menzies I.S. Intestinal permeability in coeliac disease (abstr) Gut 13 1972 847
4. Loehry C.A. Axon A.T.R. Hilton P.J. Permeability of the small intestine to substances of different molecular weight Gut 11 1970 466 470
5. Bright-Asare P. Binder H.J. Stimulation of colonic secretion of water and electrolytes by hydroxy fatty acids Gastroenterology 64 1973 81 88
6. Billich C.O. Levitan R. Effects of sodium concentration and osmolality on water and electrolyte absorption from the intact human colon J Clin Invest 48 1969 1336 1347
7. Loehry C.A. Kingham J. Baker J. Small Intestinal permeability in animals and man Gut 14 1973 683 688
8. Chadwick V.S. Phillips S.F. Hofmann A.F. Measurement of intestinal permeability using low molecular weight polyethylene glycols (PEG 400). II. Application to study of normal and abnormal permeability states in man and animals Gastroenterology 73 1977 247 251
9. Hyden S. A turbidometric method for the determination of higher polyethylene glycols in biologic materials Ann R Agric Coll Sweden 11 1955 139 145
10. Spector W.S. Handbook of Toxicity vol I 1956 WB Saunders Co Philadelphia 240
11. Carbowax, Polyethylene Glycols for Pharmaceuticals and Cosmetics 1959 Union Carbide Chemicals Co New York
12. Smyth H.F. Carpenter C.P. Shaffer C.B. The subacute toxicity and irritation of polyethylene glycols of approximate molecular weight of 200, 300 and 400 J Pharm Sci 34 1945 172 174
13. Smyth H.F. Carpenter C.P. Weil C.S. The chronic oral toxicology of the polyethylene glycols J Pharm Sci 44 1955 27 30
14. Borgstrom B. Dahlqvist A. Lundh G. Studies of intestinal digestion and absorption in the human J Clin Invest 36 1957 1521 1536
15. Technical Bulletin No. 24 State College, Pa, Applied Science Laboratories, Inc 1976
16. Roovers J. Evrard E. Vanderhaeghe H. An improved method for measuring human blood bile acids Clin Chim Acta 19 1968 449 457
17. Hardwicke J. Hulme B. Jones J.H. Measurement of glomerular permeability to polydisperse radioactively labelled macromolecules in normal rabbits Clin Sci 34 1968 505 514