The ultrastructural changes of Leishmania tropica after treatment with pentamidine

Annals of Tropical Medicine and Parasitology

Volumn 71, Issue 2, 1977, Pages 157-166

  Hentzer, Bent ^a   Kobayasi, Takasi ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

PENTAMIDINE;

ELECTRON MICROSCOPY; LEISHMANIA TROPICA; METHODOLOGY; MICROORGANISM; PHARMACOKINETICS; THERAPY;

AMIDINES; ANIMAL; LEISHMANIA; MICROSCOPY, ELECTRON; MITOCHONDRIA; PENTAMIDINE;

EID: 0017373687     PISSN: 00034983     EISSN: 13648594     Source Type: Journal    
DOI: 10.1080/00034983.1977.11687174     Document Type: Article

References (24)

1. Adler, S. & Tchernomoretz, I. (1939). The action of 4:4'-diamidino stilbene on Leishmama donovani in the Syrian hamster Cricetus auratus. Annals of Tropical Medicine and Parasitology, 33, 313-322.
2. Allison, A. C. (1968). The role of lysosomes in the action of drug and hormones. In Goldin, A., Hawking, F. & Schnitzer, R. J. Advances in Chemotherapy, 279-280, New York & London: Academic Press.
3. Baker, J. R. (1961). The distribution of nucleic acid in Trypanosoma evansi. Transactions of the Royal Society of Tropical Medicine and Hygiene, 55, 518-524.
4. Brown, K. N., Armstrong, J. A. & Valentine, R. C. (1965). The ingestion of protein molecules by blood forms of Trypanosoma rhodesiense. Experimental Cell Research, 39, 129-135.
5. Burton, P. R. & Dusanic, D. G. (1968). The fine structure and replication of the kinetoplast of Trypanosoma lewisi. Journal of Cell Biology, 39, 318-331.
6. Delain, E., Brack, C., Riou, G. & Festy, B. (1971). Ultrastructural alterations of Trypanosoma cruzi kinetoplast induced by the interaction of a trypanocidal drug (hydroxystilbamidine) with the kinetoplast DNA. Journal of Ultrastructural Research, 37, 200-218.
7. Faust, E. C., Russell, P. F. & Jung, R. C. (1970). The blood and tissue flagellates. In Craig & Faust’s Clinical Parasitology, p. 75. Philadelphia: Lea and Febiger.
8. Garnham, P. C. C. (1971). The genus of Leishmania. Bulletin of the World Health Organization, 44, 477-489.
9. Gutteridge, W. E. (1966). Chemotherapy and drug sensitivity. Further investigations on the mode of action of pentamidine. Transactions of the Royal Society of Tropical Medicine and Hygiene, 60, 120.
10. Gutteridge, W. E., Stuart, K., Williamson, D. H. & Vickerman, K. (1973). Analysis of DNA from some dyskinetoplastic species of trypanosome. Transactions of the Royal Society of Tropical Medicine and Hygiene, 67, 247.
11. Hentzer, B. & Kobayasi, T. (1977). The ultrastructure of Leishmania tropica in skin lesions. Acta Pathologica et Microbiologica Scandinavica, Sect. B. (In press).
12. Jadin, J. M. (1971). Cytologie et cytophysiologie des Trypanosomidae. Acta Zoologica et Pathologica Anlverpiensa, 54, 5-168.
13. Lopes, C. F. & De Almeida, M. A. (1968). Le traitement de la leishmaniose cutan£e amdricaine par une Pentamidine. Hospital, 73, 223-231.
14. Macadam, R. F. & Williamson, J. (1972). Drug effects on the fine structure of Trypanosoma rhodesiense-. Diamidines. Transactions of the Royal Society of Tropical Medicine and Hygiene, 66, 897-904.
15. Maria, T. A., Tafuri, W. & Brener, Z. (1972). The fine structure of different bloodstream forms of Trypanosoma cruzi. Annals of Tropical Medicine and Parasitology, 66, 423-431.
16. Markell, E. K. & Voge, M. (1971). Medical Parasitology, third edition, 128-139, Philadelphia, London. Toronto: Saunders Company.
17. Mattock, N. M. & Peters, W. (1973). Chemotherapy of leishmaniasis: A method for screening potential leishmanicides. Transactions of the Royal Society of Tropical Medicine and Hygiene, 67, 22.
18. Newton, B. A. & Le Page, R. W. F. (1967). Preferential inhibition of extranuclear deoxyribonucleic acid synthesis by the trypanocide berenil. Proceedings of the Biochemical Society, 105, 50 pp.
19. Novikoff, A. B. & Holtzman, E. (1970). Cells and organelles, 105-106, New York, London, Sydney: Holt, Runehost and Winston Inc.
20. Pham, T. D., Azar, H. A., Moscovic, E. A. & Kurban, A. K. (1970). The ultrastructure of Leishmania tropica in oriental sore. Annals of Tropical Medicine and Parasitology, 64, 1-4.
21. Preston, T. M. (1969). The form and function of the cytostome-cytopharynx of the culture forms of the elasmobranch haemoflagellate Trypanosoma raiae Laveran & Mesnil. Journal of Protozoology, 16, 320-333.
22. Rudzinska, M. A., D’Alesandro, P. A. & Trager, W. (1964). The fine structure of Leishmama donovani and the role of the kinetoplast in leishmania-leptomonal transformation. Journal of Protozoology, 11, 166-191.
23. Tracer, W. & Rudzinska, M. A. (1964). The riboflavin requirement and the effects of acriflavin on the fine structure of the kinetoplast of Leishmania tarentolae. Journal of Protozoology, 11, 133-145.
24. Yarbro, J. W. & Bornstein, R. S. (1963). An evaluation of the mechanism of action of pentamidine isethionate. Clinical Research, 16, 471.