Schedule-dependent Antitumor Effects of Methotrexate and 5-Fluorouracil

Cancer Research

Volumn 37, Issue 1, 1977, Pages 327-328

  Bertino, J R ^b   Sawicki, W L ^b   Lindquist, C A ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; METHOTREXATE;

CANCER CHEMOTHERAPY;

ANIMAL; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; FLUOROURACIL; METHOTREXATE; MICE; SARCOMA 180; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0017361019     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

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2. Bonnadonna, G., Brusamolino, E., Valagussa, P., Rossi, A., Brugnatelli, L., Brambilla, C., De Lena, M., Tancini, G., Bajetta, E., Musumeci, R., and Veronesi, U. Combination Chemotherapy as an Adjuvant Treatment in Operable Breast Cancer. New Engl. J. Med., 294: 405–410, 1976.
3. Brennan, M. J. Breast Cancer. In: E. Frei, III and J. Holland (eds.), Cancer Medicine, pp. 1769–1788. Philadelphia: Lea and Febiger, 1973.
4. Constanzi, J. J., and Coltman, C. A. Combination Chemotherapy Using Cyclophosphamide, Vincristine and 5-Fluorouracil in Solid Tumors. Cancer, 23: 589–596, 1969.
5. Kline, I., Venditti, J. M., Mead, J. A. R., Tyrer, D., and Golon, A. The Antileukemic Effectiveness of 5-Fluorouracil and Methotrexate in the Combination Chemotherapy of Advanced Leukemia L1210 in Mice. Cancer Res., 26: 848–852, 1966.
6. Santi, D. V., McHenry, C. S., and Sommer, A. Mechanism of Interaction of thymidylate Synthetase with 5-Fluorodeoxyuridylate. Biochemistry, 13: 471–480, 1974.
7. Tattersall, M. H. N., Jackson, R. C. Connors, T. A., and Harrup, K. R. Combination Chemotherapy: The Interaction of Methotrexate and 5-Fluorouracil. European J. Cancer, 9: 733–739, 1973.