Experimental Antiulcer Drugs. 1. Indole-1-alkanamides and Pyrrole-1-alkanamides

Journal of Medicinal Chemistry

Volumn 20, Issue 4, 1977, Pages 537-540

  Bell, Malcolm R ^a   Zalay, Andrew W ^a   Oesterlin, Rudolf ^a   Clemans, Stephen D ^a   Dumas, Donald J ^a   Bradford, James C ^a   Rozitis, Janis ^a  

^a EASTMAN KODAK COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLINDOLE; 2,3 DIMETHYLINDOLE 1 ACETAMIDE; ATROPINE; CIMETIDINE; DIMETHYLINDOLE; INDOLE 1 ALKANAMIDE DERIVATIVE; INDOLEALKYLAMINE; PYRROLE 1 ALKANAMIDE DERIVATIVE; PYRROLEALKYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; DOSE RESPONSE; DRUG ANALYSIS; DRUG COMPARISON; DRUG RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MYDRIASIS; ORAL DRUG ADMINISTRATION; RAT; STOMACH ACID SECRETION; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY;

ANIMALS; ANTI-ULCER AGENTS; DOGS; GASTRIC JUICE; GUINEA PIGS; HEART RATE; INDOLES; MALE; MICE; PUPIL; PYRROLES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; VOMITING;

EID: 0017327835     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00214a015     Document Type: Article

References (11)

1. H. Shay, S. A. Komarov, S. S. Fels, D. Meranze, M. Gruenstein, and H. Siplet, Gastroenterology, 5, 43 (1945).
2. J. H. Thompson, “Search for New Drugs”, Vol. 6, Allan A. Rubin, Ed., Marcel Dekker, New York, N.Y., 1972.
3. P. Bass, Ado. Drug Res., 8, 205 (1974).
4. E. Leete, J. Am. Chem. Soc., 81, 6023 (1959).
5. R. W. Brimblecombe, W. A. M. Duncan, G. J. Durant, J. C. Emmett, C. R. Ganellin, and M. E. Parsons, J. Int. Med. Res., 3, 86 (1975).
6. S. Swaminathan and S. Ranganathan, J. Org. Chem., 22, 70 (1957).
7. C. Y. Almond and F. G. Mann, J. Chem. Soc., 1870 (1964).
8. A. H. Jackson and A. E. Smith, J. Chem. Soc., 5510 (1964).
9. M. Julia and J. Lenzi, Bull. Soc. Chim. Fr., 2267 (1962).
10. A. Wolf, German Patent 876 237 (1953).
11. J. W. Blade, W. A. M. Duncan, J. C. Emmett, C. R. Ganellin, T. Hesselbo, M. E. Parsons, and J. H. Wyllie, Agents Actions, 3, 133 (1973).