Etodolic Acid and Related Compounds. Chemistry and Antiinflammatory Actions of Some Potent Di- and Trisubstituted 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetic Acids

Journal of Medicinal Chemistry

Volumn 19, Issue 3, 1976, Pages 391-395

  Demerson, Christopher A ^a   Humber, Leslie G ^a   Philipp, Adolf H ^a   Martel, Rene R ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDOMETACIN; PHENYLBUTAZONE; PYRANOINDOLE DERIVATIVE; PYRANO[3,4 L]INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTHRITIS; ARTICLE; DRUG ANALYSIS; DRUG COMPARISON; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERANCE; IN VITRO STUDY; INFLAMMATION; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORAL DRUG ADMINISTRATION; RAT; STOMACH ULCER; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY; ULCER;

EID: 0017230797     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00225a010     Document Type: Article

References (9)

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3. I. I. Grandberg and T. P. Moskvina, Khim. Geterotsikl. Soedin, 1366 (1972)
4. R. R. Martel, J. Klicius, and F. Herr, Can. J. Physiol. Pharmacol., 52, 791 (1974)
5. D. J. Finney, “Probit Analysis”, University Press, Cambridge, Mass., 1947
6. C. A. Winter, E. A. Risley, and G. W. Nuss, Proc. Soc. Exp. Biol. Med., III, 544 (1962)
7. W. Robinson, R. R. Martel, M. Kraml, and D. Dvornik, manuscript in preparation
8. R. R. Martel and J. Klicius, Can. J. Physiol. Pharmacol., in press
9. R. Paul, M. Fluchaire, and G. Collardeau, Bull. Soc. Chim. Fr., 668 (1950)