Septicemia and Meningitis in Children Splenectomized for Hodgkin's Disease

New England Journal of Medicine

Volumn 295, Issue 15, 1976, Pages 798-800

  Chilcote, Robert R ^a   Baehner, Robert L ^a   Hammond, Denman ^a  

^a Children's Cancer Study Group ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PENICILLIN G;

CHILD; DIAGNOSIS; HAEMOPHILUS INFLUENZAE; HODGKIN DISEASE; MAJOR CLINICAL STUDY; MENINGITIS; MICROORGANISM; NEISSERIA MENINGITIDIS; SEPTICEMIA; SPLENECTOMY; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE; THERAPY;

EID: 0017178646     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM197610072951502     Document Type: Article

References (28)

1. Hays DM, Karon M, Isaacs H, et al: Hodgkin disease: technique and results of staging laparotomy in childhood. Arch Surg 106: 507–512, 1973
2. Glatstein E, Guernsey JM, Rosenberg SA, et al: The value of laparotomy and splenectomy in the staging of Hodgkin's disease. Cancer 24: 709–718, 1969
3. Filler RM, Jaffe N, Cassady JR, et al: Experience with clinical and operative staging of Hodgkin's disease in children. J Pediatr Surg 10: 321–328, 1975
4. Schimpff SC, O'Connell MJ, Greene WH, et al: Infections in 92 splenectomized patients with Hodgkin's disease. Am J Med 59: 695–701, 1975
5. Desser RK, Ultmann JE: Risk of severe infection in patients with Hodgkin's disease or lymphoma after diagnostic laparotomy and splenectomy. Ann Intern Med 77: 143–146, 1972
6. Ravry M, Maldonado N, Vélez-García E, et al: Serious infection after splenectomy for the staging of Hodgkin's disease. Ann Intern Med 77: 11–14, 1972
7. Nixon DW, Aisenberg achéal: Fatal Hemophilus influenzae sepsis in an asymptomatic splenectomized Hodgkin's disease patient. Ann Intern Med 77: 69–71, 1972
8. Donaldson SS, Moore MR, Rosenberg SA, et al: Characterization of postsplenectomy bacteremia among patients with and without lymphoma. N Engl J Med 287: 69–71, 1972
9. Rosenstock JG, D'Angio GJ, Kiesewetter WB: The incidence of complications following staging laparotomy for Hodgkin's disease in children. Am J Roentgenol Radium Ther Nucl Med 120: 531–535, 1974
10. Balfanz JR, Nesbit ME, Jarvis C, et al: Overwhelming sepsis following splenectomy for trauma. J Pediatr 88: 458–460, 1976
11. Singer DB: Postsplenectomy sepsis. Perspect Pediatr Pathol 1: 285–311, 1973
12. Eraklis AJ, Filler RM: Splenectomy in childhood: a review of 1413 cases. J Pediatr Surg 7: 382–388, 1972
13. King H, Shumacker HB Jr: Splenic studies I. Susceptibility to infection after splenectomy performed in infancy. Ann Surg 136: 239–242, 1952
14. Smith CH, Erlandson ME, Stern G, et al: Postsplenectomy infection in Cooley's anemia: an appraisal of the problem in this and other blood disorders, with consideration of prophylaxis. N Engl J Med 266: 737–743, 1962
15. Kevy SV, Tefft M, Vawter GF, et al: Hereditary splenic hypoplasia. Pediatrics 42: 752–757, 1968
16. Kabins SA, Lerner C: Fulminant pneumococcemia and sickle cell anemia. JAMA 211: 467–471, 1970
17. Chilcote RR, Baehner RL: Infection in childhood cancer: experience in management of infection in acute leukemia, Clinical Management of Cancer in Children. Edited by C Pochedly. Acton Massachusetts, Publishing Sciences Group, 1975, pp 33–45
18. Bodey GP, Buckley M, Sathe YS, et al: Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 64: 328–340, 1966
19. Casazza AR, Duvall CP, Carbone PP: Summary of infectious complications occurring in patients with Hodgkin's disease. Cancer Res 26: 1290–1296, 1966
20. Lobell M, Boggs DR, Wintrobe MM: The clinical significance of fever in Hodgkin's disease. Arch Intern Med 117: 335–342, 1966
21. Schulkind ML, Ellis EF, Smith RT: Effect of antibody upon clearance of 125I-labeled pneumococci by the spleen and liver. Pediatr Res 1: 178–184, 1967
22. Van Rooijen N: Immune complexes in the spleen: the difference between competitive inhibition of immune complex trapping in spleen follicles and inhibition by paratyphoid vaccine. Immunology 28: 1155–1163, 1975
23. Bardach MJ: Recherches sur le role de la rate dans les maladies infectieuses. Ann Inst Pasteur 3: 577–603, 1889
24. Ellis EF, Smith RT: The role of the spleen in immunity: with special reference to the post-splenectomy problem in infants. Pediatrics 37: 111–119, 1966
25. Likhite VV: Opsonic and leukophilic γ globulin in chronically splenectomized rats with and without heterotropic autotransplanted splenic tissue. Nature 253: 742–744, 1975
26. Sheagren JN, Block JB, Wolff SM: Reticuloendothelial system phagocytic function in patients with Hodgkin's disease. J Clin Invest 46: 855–862, 1967
27. Levy R, Kaplan HS: Impaired lymphocyte function in untreated Hodgkin's disease. N Engl J Med 290: 181–186, 1974
28. King GW, Yanes B, Hurtubise PE, et al: Immune function of successfully treated lymphoma patients. J Clin Invest 57: 1451–1460, 1976