Role of insulin resistance in adipose tissue and liver in the pathogenesis of endogenous hypertriglyceridaemia in man

Diabetologia

Volumn 12, Issue 6, 1976, Pages 563-571

  Kissebah, A H ^a   Alfarsi, S ^a   Adams, P W ^a   Wynn, V ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

diabetic lipodystrophy; endogenous hypertriglyceridaemia; free fatty acids (FFA); insulin; Insulin resistance; maturity onset diabetes; very low density lipoproteins (VLDL) VLDL B apoproteins

Indexed keywords

APOPROTEIN; FATTY ACID; INSULIN; VERY LOW DENSITY LIPOPROTEIN;

ADIPOSE TISSUE; DIABETES MELLITUS; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; LIPODYSTROPHY; LIVER; MAJOR CLINICAL STUDY;

ADIPOSE TISSUE; ADULT; AGED; APOLIPOPROTEINS; DIABETES MELLITUS; FATTY ACIDS, NONESTERIFIED; HUMAN; HYPERINSULINISM; HYPERLIPIDEMIA; INSULIN RESISTANCE; LIPODYSTROPHY; LIPOPROTEINS, VLDL; LIVER; MALE; MIDDLE AGE; TRIGLYCERIDES;

EID: 0017149822     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/BF01220632     Document Type: Article

References (38)

1. Glucose, insulin and triglyceride responses to high and low carbohydrate diets in man
2. Role of insulin in endogenous hypertriglyceridemia
3. Reappraisal of the role of insulin in hypertriglyceridemia
4. Lipid transport and insulin resistance
5. Genetically transmitted obesity in rodents
6. Insulin-receptor interaction in the obese-hyperglycaemic mouse
7. The kinetics of plasma free fatty acid and triglyceride transport in patients with idiopathic hypertriglyceridaemia and their relation to carbohydrate metabolism
8. Transport kinetics of plasma free fatty acids, very low density lipoprotein triglycerides and apoprotein in patients with endogenous hypertriglyceridaemia: Effects of 2, 2-Dimethyl, 5 (2, 5-xylyoxy) valeric acid therapy
9. Precursors of plasma triglyceride fatty acid in humans. Effects of glucose consumption, clofibrate administration and alcoholic fatty liver
10. Precursors of plasma triglyceride fatty acids in obesity
11. Practical methods for plasma lipoprotein analysis
12. Efficient trace-labelling of proteins with iodine
13. Metabolic non-homogeneity of lecithin and cholesterol in aortae
14. A rapid electrophoretic technique for identification of subunit species of apoproteins in serum lipoproteins
15. The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations
16. Protein measurement with folinphenol reagent
17. Plasma free fatty acid and triglyceride transport kinetics in man
18. Titration of free fatty acid of plasma. A study of current methods and a new modification
19. New automated method for measuring glucose by glucose oxidase
20. A sensitive precise radio-immuno assay of serum insulin relying on charcoal separation of bound and free hormone moieties
21. Some effects of oral contraceptives on carbohydrate metabolism
22. The fluorimetric assay of triglyceride by a semi-automated method
23. An evaluation of cholesterol determination in serum and serum lipoprotein fractions by a semiautomated fluorimetric method
24. Polymorphism of plasma triglyceride kinetics in normal human adult subjects
25. Quantitative evaluation of free fatty acid and triglyceride fatty acid metabolism in man
26. Effects of insulin pretreatment on glucose and lipid metabolism of liver slices from normal rats
27. Stimulation by insulin of the incorporation of U14 C-glucose into lipids released by the liver
28. Effects of insulin on glucose metabolism by the perfused normal rat liver
29. Effect of insulin in hypertri glyceridaemia
30. Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridaemic and hypertriglyceridamic humans
31. Determination of splanchnic secretion rate of plasma triglycerides and of total and splanchnic turnover of plasma free fatty acids in man
32. Diurnal patterns of triglycerides, free fatty acids, blood sugar, and insulin during carbohydrate induction in man and their modification by nocturnal suppression of lipolysis
33. Diurnal patterns of plasma triglycerides and free fatty acids in normal subjects and in patients with endogenous (type IV) hyperlipo proteinaemia
34. Plasma triglyceride transport kinetics in diabetes mellitus
35. Adipocyte metabolism in endogenous hypertri glyceridaemia
36. Effects of feeding states on lipid radioacitivity in liver, muscle and adipose tissue after injection of labelled glucose in the rat
37. Adult human adipose tissue cellularity and metabolism