Studies on phenolic steroids in human subjects. Xx. in vivo conjugation and metabolism of estradiol-17β in the human kidney

Journal of Clinical Endocrinology and Metabolism

Volumn 43, Issue 6, 1976, Pages 1294-1300

  Honjo, Hideo ^a   Barua, Nil R ^a   Osawa, Yoshio ^a   Kirdani, Rashad Y ^a   Sandberg, Avery A ^a  

^a HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RADIOISOTOPE; STEROID HORMONE; DRUG DERIVATIVE; ESTRADIOL;

ESTRADIOL C 14; ESTRADIOL H 3; IN VITRO STUDY; KIDNEY; METHODOLOGY; NORMAL HUMAN; NORMAL VALUE; STEROID CONJUGATE; STEROID URINE LEVEL; THEORETICAL STUDY; ARTICLE; HUMAN; METABOLISM; TIME; URINE;

ESTRADIOL; HUMAN; KIDNEY; TIME FACTORS;

EID: 0017094110     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jcem-43-6-1294     Document Type: Article

References (26)

1. Kirdani, R. Y., D. Sampson, G. P. Murphy, and A. A. Sandberg, Studies on phenolic steroids in human subjects. XVI. Role of the kidney in the disposition of estriol, J Clin Endocrinol Metab 34: 546, 1972.
2. Nagatomi, K., Y. Osawa, R. Y. Kirdani, and A. A. Sandberg, Studies on phenolic steroids in human subjects. XVII. The kidney and fate of 15ahydroxyestrogens, J Clin Endocrinol Metab 37: 887, 1973.
3. Yamamoto, Y., M. Ishihara, R. Y. Kirdani, Y. Osawa, and A. A. Sandberg, Studies on phenolic steroids in human subjects. XIX. Renal conjugation of 15α-hydroxyestradiol-3-sulfate, J Clin Endocrinol Metah 43: 144, 1976.
4. 3H]estradiol-17β in the human subject, J Steroid Biochem 5: 15, 1974.
5. 3H-17-glucosiduronate by the human female, Steroids 13: 679, 1969.
6. Musey, P. I., and R. Hobkirk, Metabolism of 17β- estradiol-17-glucosiduronate in the human female, Clin Res 18: 721, 1970 (Abstract).
7. Musey, P. I., R. N. Green, and R. Hobkirk, The role of an enterohepatic system in the metabolism of 17β-estradiol-17-glucosiduronate in the human female, J Clin Endocrinol Metab 35: 448, 1972.
8. Hobkirk, R., and M. Nilsen, Metabolism of 17β- estradiol to 17β-estradiol-3-glucosiduronate and 17β-estradiol-17-glucosiduronate by the normal human female, J Clin Endocrinol Metab 32: 779, 1971.
9. Honjo, H., M. Ishihara, R. Y. Kirdani, and A. A. Sandberg, Renal conjugation and metabolism of estradiol-17β and estrone, Program of the Endocrine Society 57th Annual Meeting, New York, New York, June 18-20, 1975, p. 65 (Abstract).
10. Honjo, H., M. Ishihara, Y. Osawa, R. Y. Kirdani, and A. A. Sandberg, In vivo and in vitro conjugation and metabolism of estrogens by the baboon kidney, Endocrinology (In press).
11. Seldinger, S. I., Catheter replacement of the needle in percutaneous arteriography, a new technique, Acta Radiol 39: 368, 1953.
12. Sa’at, Y. A., and W. R. Slaunwhite Jr., Biosynthesis of estrone and estradiol 3-glucosiduronates, Steroids 13: 545, 1969.
13. Boon, D. A., N. J. Wagner, and W. R. Slaunwhite Jr., Characterization of estriolglucosiduronic acid formed in vitro by human liver, Steroids 13: 559, 1969.
14. Goebelsmann, U., E. Diczfalusy, J. Katz, and M. Levitz, Biosynthesis of radioactive estriol-3- glucosiduronate by guinea pig liver homogenate, Steroids 6: 859, 1965.
15. Kirdani, R. Y., and R. L. Priore, Statistical analysis of data from counter-current distribution. IV. Identification of compounds, Anal Biochem 35: 1, 1970.
16. Kirdani, R. Y., and R. L. Priore, Statistical analysis of data from counter-current distribution. V. The isotope effect, Anal Biochem 35: 13, 1970.
17. Breuer, H., and D. Wassendorf, Enzymatische Bildung von Östradiol-(17β)-glucuroniden in der Mikrosomen — Fraktion der Kaninchenleber, Hoppe Seylers Z Physiol Chem 345: 1, 1966.
18. 14C] estrone, Can J Biochem 53: 1085, 1975.
19. Mellor, J. D., and R. Hobkirk, In vitro synthesis of estrogen glucuronides and sulfates by human renal tissue, Can J Biochem 53: 779, 1975.
20. Hobkirk, R., J. D. Mellor, and M. Nilsen, In vitro metabolism of 17β-estradiol by human liver tissue, Can J Biochem 53: 903, 1975.
21. Hobkirk, R., R. N. Green, M. Nilsen, and B. A. Jennings, Formation of estrogen glucosiduronates by human kidney homogenates, Can J Biochem 52: 9, 1974.
22. Huhtaniemi, I., and R. Vihko, Steroid metabolism in kidney tissue. I. Endogenous neutral steroids in foetal kidneys and studies on their formation, Acta Endocrinol (Kbh) 71: 530, 1972.
23. Støa, K. F., and M. Levitz, Comparison of the conjugated metabolites of intravenously andintraduodenally administered oestriol, Acta Endocrinol (Kbh) 57: 657, 1968.
24. 35S in a woman, J Clin Endocrinol Metab 29: 615, 1969.
25. Støa, K. F., and P. A. Skulstad, Biliary and urinary metabolites of intravenously and intraduodenally administered 17β-oestradiol and oestriol, Steroids Lipids Res 3: 299, 1972.
26. Slaunwhite, W. R., R. Y. Kirdani, and A. A. Sandberg, Metabolic aspects of estrogens in man, In Greep, R. O. (ed.), Handbook of Physiology, section 7, vol. II, American Physiological Society, Washington, D.C., 1973, p. 485.