Antipsychotic drug doses and neuroleptic/dopamine receptors

Nature

Volumn 261, Issue 5562, 1976, Pages 717-719

  Seeman, P ^a   Lee, T ^a   Chau Wong, M ^a   Wong, K ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

APOMORPHINE; BENPERIDOL; BUTACLAMOL; CHLORPROMAZINE; CLOZAPINE; DOPAMINE; DOPAMINE RECEPTOR; DROPERIDOL; DRUG RECEPTOR; FLUPHENAZINE; LENPERONE; MOLINDONE; NEUROLEPTIC AGENT; PIMOZIDE; PROCHLORPERAZINE; PROMAZINE; PROMETHAZINE; RADIOISOTOPE; SPIPERONE; THIORIDAZINE; TIOTIXENE; TRAZODONE; TRIFLUOPERAZINE; TRIFLUPERIDOL;

CLOMACRAN; DOPAMINE H 3; DOSE RESPONSE; DRUG COMPARISON; DRUG MECHANISM; DRUG RESPONSE; DRUG THERAPY; HALOPERIDOL H 3; METIAPINE; PHARMACOKINETICS; PSYCHOSIS; STEREOSPECIFICITY; THEORETICAL STUDY; THERAPY;

ANIMAL; BINDING, COMPETITIVE; CATTLE; CAUDATE NUCLEUS; DOPAMINE; HALOPERIDOL; HUMAN; RATS; RECEPTORS, DRUG; SCHIZOPHRENIA; TRANQUILIZING AGENTS;

EID: 0017068246     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/261717a0     Document Type: Article

References (18)

1. Van Rossum, J. M., Arch. int. Pharmacodyn., 160, 492–494 (1966).
2. Iversen, L. L., Science, 188, 1084–1089 (1975).
3. Horn, A. S., Post, M. L., and Kennard, O., J. Pharm. Pharmac., 27, 553–563 (1975).
4. Matthysse, S., Fedn Proc., 32, 200–204 (1973).
5. Seeman, P., Wong, M., and Lee, T., Fedn Proc., 33, 246 (1974).
6. Seeman, P., Wong, M., and Tedesco, J., Proc. Neurosci. Soc., 5, 405 (1975).
7. Seeman, P., Chau-Wong, M., Tedesco, J., and Wong, K., Proc. natn. Acad. Sci. U.S.A., 72, 4376–4380 (1975).
8. Creese, I., Burt, D. R., and Snyder, S. H., Life Sci., 17, 993–1002 (1975).
9. Burt, D. R., Enna, S., Creese, I., and Snyder, S. H., Proc. natn. Acad. Sci. U.S.A., 72, 4655–4659 (1975).
10. Seeman, P., Pharmac. Rev., 24, 583–655 (1972).
11. Seeman, P., Staiman, A., and Chau-Wong, M., J. Pharmac. exp. Ther., 190, 123–130 (1974).
12. Seeman, P., and Lee, T., Science, 188, 1217–1219 (1975).
13. Seeman, P., in Antipsychotic Drugs, Pharmacodynamics and Pharmacokinetics (edit. by Sedvall, G.) (Pergamon, Oxford, in the press).
14. Forsman, A., Mrtensson, E., Nyberg, G., and Ohman, R., Naunyn–Schmiedeberg's Arch. Pharmac., 286, 113–124 (1974).
15. Sakalis, G., Curry, S. H., Mould, G. P., and Lader, M. H., Clin. Pharmac. Ther., 13, 931–946 (1972).
16. Cooper, S. F., Albert, J.-M., Hillel, J., and Caille, G., Curr. Ther. Res., 15, 73–77 (1973).
17. Pecknold, J. C., Ban, T. A., Lehmann, H. E., and Climan, M., Int. J. clin. Pharmac., 11, 299–303 (1975).
18. Simpson, G. M., and Varga, V., Curr. Ther. Res., 16, 477–482 (1974).