Copper Chelates as Possible Active Forms of the Antiarthritic Agents

Journal of Medicinal Chemistry

Volumn 19, Issue 1, 1976, Pages 135-148

  Sorenson, John R J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTHRANILIC ACID; COPPER ACETATE; DEXAMETHASONE SODIUM PHOSPHATE; DRUG; HYDROCORTISONE; HYDROCORTISONE SODIUM PHOSPHATE; HYDROCORTISONE SODIUM SUCCINATE; NIFLUMIC ACID; PENICILLAMINE; TRYPTOPHAN;

ARTHRITIS; COPPER CHELATE; DOSE RESPONSE; DRUG COMPARISON; DRUG RESPONSE; DRUG SCREENING; DRUG SYNTHESIS; DRUG TOXICITY; FENAMOLE; INFLAMMATION; LIVER FUNCTION; METHODOLOGY; MOUSE; ORAL DRUG ADMINISTRATION; PEPTIC ULCER; RAT; STOMACH ULCER; SUBCUTANEOUS DRUG ADMINISTRATION; THEORETICAL STUDY;

ACETATES; ANIMAL; ANTHRANILIC ACIDS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, RHEUMATOID; CHELATING AGENTS; COPPER; DISEASE MODELS, ANIMAL; EDEMA; GRANULOMA; HYDROCORTISONE; LETHAL DOSE 50; MICE; RATS; SALICYLIC ACIDS; TRYPTOPHAN; ULCER;

EID: 0016916478     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00223a024     Document Type: Article

References (55)

1. R. L. Aspinal and S. Eich, personal communications
2. E. J. Underwood, “Trace Elements in Human and Animal Nutrition”, 3rd ed, Academic Press, New York, N.Y., 1971, p 57
3. G. W. Evans, Physiol. Rev., 53 (no. 3), 535 (1973)
4. H. Scheinberg, Fed. Proc., Fed. Am. Soc. Exp. Biol., 20 (no. 3, part II), 179 (1961)
5. J. Cuatrecasas, Med. Clin. (Barcelona), 44, 211 (1965)
6. A. S. Kartsak, J. Can. Med. Assoc., 96 (no. 6), 361 (1967)
7. I. Sternlieb, Nature (London), 216, 824 (1967)
8. P. F. Neumann, Nature (London), 213, 775 (1967)
9. A. Grollman, “Pharmacology and Therapeutics”, 3rd ed, Lea and Febiger, Philadelphia, Pa., 1958, p 911
10. F. R. DiPalma, “Drill's Pharmacology in Medicine”, 3rd ed, McGraw-Hill, New York, N.Y., 1965, p 875
11. C. M. Harris and S. E. Livingston, “Chelating Agents and Metal Chelates”, F. P. Dwyer and D. P. Mellor, Ed, Academic Press, New York, N.Y., 1964, p 95
12. C. A. Winter, E. A. Risley, and G. W. Nuss, J. Pharmacol. Exp. Ther., 141, 369 (1963)
13. R. Meier, W. Schuler, and P. Desaulles, Experientia, 6, 469 (1950)
14. R. L. Aspinal and P. S. Cammarata, Nature (London), 224, 1320 (1969)
15. C. White, Biometrics, 8, 33 (1952)
16. L. C. Miller and M. L. Tainter, Proc. Soc. Exp. Biol. Med., 52, 261 (1944)
17. D. Seligson, J. Marino, and E. Dodson, Clin. Chem., 3, 638 (1957)
18. S. Reitman and S. Frankel, Am. J. Clin. Pathol., 28, 56 (1957)
19. L. Manojlovic-Muir, Chem. Commun., 1057 (1967)
20. M. Kato, H. B. Jonassen, and J. C. Fanning, Chem. Rev., 64, 99(1964)
21. A. E. Hansen and C. J. Ballhausen, Trans. Faraday Soc., 61, 631 (1965)
22. L. Dubicki and R. L. Martin, Inorg. Chem., 5, 2203 (1966)
23. D. M. L. Goodgame, N. J. Hill, D. F. Marsham, A. C. Skapski, M. L. Smart, and P. G. H. Troughton, Chem. Commun., 629 (1969)
24. R. W. Jotham and S. F. A. Kettle, Inorg. Chem., 9, 1390 (1970)
25. J. Lewis and R. G. Wilkins, “Modern Coordination Chemistry: Principals and Methods”, Interscience, New York, N.Y., 1960, p 435
26. F. A. Cotton and G. Wilkinson, “Advanced Inorganic Chemistry”, 3rd ed, Interscience, New York, N.Y., 1972, pp 620 and 918
27. J. E. Huheey, “Inorganic Chemistry: Principals of Structure and Reactivity”, Harper and Row, New York, N.Y., 1972, p 548
28. J. N. van Niekerk and F. R. L. Schoening, Acta Crystallogr., 6, 227 (1953)
29. L. S. Foster and C. J. Ballhausen, Acta Chem. Scand., 8, 1275 (1964)
30. I. G. Ross and J. Yates, Trans. Faraday Soc., 55, 1064 (1959)
31. E. W. Wilson, Jr., and R. B. Martin, Arch. Biochem. Biophys., 142, 445 (1971)
32. H. Sakurai, A. Yokoyama, and H. Tanaka, Chem. Pharm. Bull., 18, 2373 (1970)
33. H. E. Christensen, “The Toxic Substances List”, 1973 ed, U.S. Department of Health, Education and Welfare, U.S.Public Health Service, NIOSH, Rockville, Md., June 1973, p 33
34. W. C. Kuzell, Annu. Rev. Pharmacol., 8, 368 (1968)
35. H. Shay, S. A. Komarov, S. S. Fels, D. Meranze, M. Gruenstein, and H. Siplet, Gastroenterology, 5, 43 (1945)
36. A. Robert, J. E. Nezamis, and J. P. Phillips, Proc. Soc. Exp. Biol. Med., 99, 443 (1958)
37. R. Osterberg, Coord. Chem. Rev., 12, 318 (1974)
38. F. Hanic, D. Stempelova, and K. Hanicova, Acta Crystallogr., 17, 633 (1964)
39. G. A. Barclay and C. H. L. Kennard, J. Chem. Soc., 5244 (1961)
40. W. H. C. Rueggeberg, G. N. Jarman, and R. B. Wearn, J. Am. Chem. Soc., 69, 1222 (1947)
41. W. R. Walker, Y. L. Shaw, and C. Norman, J. Coord. Chem., 3, 77 (1973)
42. W. R. Walker, R. Reeves, and D. J. Kay, Search, 6, 134 (1975)
43. L. L. Wiesel, Metabolism, 8, 256 (1959)
44. L. M. Hofmann, H. A. Wagner, and R. S. Jacobs, Arch. Int. Pharmacodyn., 165, 476 (1967)
45. M. L. Anson, J. Gen. Physiol., 22, 79 (1938)
46. G. H. Acheson and S. A. Pereria, J. Pharmacol. Exp. Ther., 87, 273 (1946)
47. L. C. Miller, T. J. Becker, and N. L. Tainter, J. Pharmacol. Exp. Ther., 92, 260 (1948)
48. E. Dobrin, “Industrial Pharmacology, Volume 1, Neuroleptics”, S. Fielding and H. Lai, Ed., Futura Publishers, Mount Kisco, N.Y., 1974, p 56
49. W. H. Carnes, Fed. Proc., Fed. Am. Soc. Exp. Biol., 30, 995 (1971)
50. S. F. Townsend, Am. J. Anat., 109, 133 (1961)
51. S. F. Townsend, personal communication.
52. M. H. McAdoo, A. M. Dannenberg, Jr., C. J. Hayes, S. P. James, and J. H. Sanner, Infect. Immunol., 7, 655 (1973)
53. A. L. Willis, personal communication
54. R. E. Lee and W. E. M. Lands, Biochim. Biophys. Acta, 260, 203 (1972)
55. I. S. Maddox, Biochim. Biophys. Acta, 306, 74 (1973)