Chymoral in the treatment of lumbar disc prolapse

Rheumatology

Volumn 14, Issue 3, 1975, Pages 186-190

  Gibson, T ^a   Dilke, T F W ^a   Grahame, R ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CHYMOTRYPSIN; PLACEBO; TRYPSIN;

CHYMORAL; DRUG THERAPY; LUMBAR DISK HERNIA; MAJOR CLINICAL STUDY; PAIN; THERAPY;

ADULT; CHYMOTRYPSIN; CLINICAL TRIALS; DRUG EVALUATION; FEMALE; HUMAN; INTERVERTEBRAL DISK DISPLACEMENT; MALE; MIDDLE AGE; PLACEBOS; TRYPSIN;

EID: 0016824336     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/14.3.186     Document Type: Article

References (19)

1. Ambrus, J. L., Lassman, H. B. and Marchi, J. H. (1967) “Absorption of Exogenous and Endogenous Proteolytic Enzymes”. Clin. Pharmacol. Ther. 8,362.
2. Blonstein, J. L. (1967) “Oral Enzyme Tablets in the Treatment of Boxing Injuries”. Practitioner 198, 547.
3. Boyne, P. S. and Medhurst, H. (1967) “Oral Anti-inflammatory Enzyme Therapy in Injuries in Professional Footballers”. Practitioner 198, 543.
4. Dilke, T. F. W., Burry, H. C. and Grahame, R. (1973) “Extradural Corticosteroid Injection in Management of Lumbar Nerve Root Compression”. Br. med. J. 2, 635.
5. Dixon, A. St. J. (1973) “Progress and Problems in Back Pain Research”. Rheumatol. Rehabil. 12, 165.
6. Gaspardy, G., Balint, G., Mrrusov A. M. and Lorincz, G. (1971) “Treatment of Sciatica due to Intervertebral Disc Herniation with Chymoral Tablets”. Rheum, phys. Med. 11,14.
7. Fodor, I., Keller, M. (1968) “Résultats des examens histologiques et histochimiques des rats traités a l’alphachymotrypsine’. Rev. Rhum. 35,534.
8. Hingorani, K. (1968) “Oral Enzyme Therapy in Severe Back Pain”. Br. J. Clin. Pract. 22, 209.
9. Innerfesld, I. (1957) “The Anti-inflammatory Effect of Parenterally Administered Proteases”. Ann. N. Y. Acad. Sci. 68, 167.
10. Angrist, A. and Schwartz, A. (1953) “Parenteral Administration of Trypsin”. J. Am. med. Assoc. 152, 597.
11. Kendall, P. H. and Jenkins, J. M. (1968) “Lumbar Isometric Flexion Exercises”. Physiotherapy 54, 3.
12. Lichtman, A. L. (1957) “Clinical Experience with Trypsin”. Ann. N. Y. Acad. Sci. 68,196.
13. Lee, K. K., Larsen, R. D. and Posch, J. L. (1967) “Evaluation of an Oral Proteolytic Enzyme in Operations upon the Hand”. Surg. Gynecol. Obstet. 125,595.
14. Lendahl, O. and Rexed, B. (1951) “Histological Changes in Spinal Nerve Roots of Operated Cases of Sciatica”. Acta orthop. scand. 22,232.
15. Macrae, I. F. and Wright, V. (1969) “Measurement of Back Movement”. Ann. rheum. Dis. 28, 584.
16. Martin, G. J., Brendel, R. and Beeler, J. M. (1954) “Inhibition of Egg White Edema by Proteolytic Enzymes”. Proc. Soc. exp. Biol. 86,636.
17. Moll, J. M. H., Liyange, S. P. and Wright, V. (1972) “An Objective Clinical Method to Measure Spinal Extension”. Rheum, phys. Med. 11,293.
18. Nordby, E. J. and Lucas, G. L. (1973) “A Comparative Analysis of Lumbar Disc Disease Treated by Laminectomy or Chemonucleolysis”. Clin. Orthop. 90,119.
19. Yates, D. A. H. (1964) “Unilateral Lumbo-sacral Root Compression”. Arm. phys. Med. 7,169.