Metabolic reduction of naltrexone I. Synthesis, separation and characterization of naloxone and naltrexone reduction products and qualitative assay of urine and bile following administration of naltrexone, α naltrexol, or β naltrexol

Research Communications in Chemical Pathology and Pharmacology

Volumn 12, Issue 1, 1975, Pages 43-65

  Malspeis, L ^a   Bathala, M S ^a   Ludden, T M ^a   Bhat, H B ^b   Frank, S G ^b   Sokoloski, T D ^b   Morrison, B E ^b   Reuning, R H ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NALOXONE; NALTREXOL; NALTREXONE; NALTREXONE H 3; RADIOISOTOPE; UNCLASSIFIED DRUG;

ARTICLE; BILE; DOG; DRUG ANALYSIS; DRUG DETERMINATION; DRUG EXCRETION; DRUG METABOLISM; DRUG SYNTHESIS; DRUG URINE LEVEL; GALLBLADDER; GAS LIQUID CHROMATOGRAPHY; GUINEA PIG; HUMAN; MONKEY; MOUSE; NORMAL HUMAN; PHARMACOKINETICS; RABBIT; RAT; THEORETICAL STUDY; THIN LAYER CHROMATOGRAPHY; URINE;

ANIMALS; BILE; CHROMATOGRAPHY, GAS; CHROMATOGRAPHY, THIN LAYER; CIRCULAR DICHROISM; DOGS; GUINEA PIGS; HAPLORHINI; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NALOXONE; NALTREXONE; OPTICAL ROTATION; OXIDATION-REDUCTION; RATS; STEREOISOMERISM;

EID: 0016753944     PISSN: 00345164     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)