Interaction of spironolactone and digitalis with the 5α dihydrotestosterone (DHT)1 receptor of rat ventral prostate

Endocrinology

Volumn 97, Issue 6, 1975, Pages 1521-1527

  Pita, J C ^a   Lippman, M E ^a   Thompson, E B ^a   Loriaux, D L ^b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANTIANDROGEN; CANRENOIC ACID; CANRENONE; DEXAMETHASONE; DIGITALIS; DIGITOXIGENIN; DIGOXIN; DRUG RECEPTOR; ESTRADIOL; HORMONE RECEPTOR; RADIOISOTOPE; SPIRONOLACTONE; TESTOSTERONE;

ANDROSTANOLONE H 3; DRUG INTERACTION; DRUG METABOLISM; IN VITRO STUDY; PROSTATE; PROSTATE VENTRAL LOBE; RAT; THEORETICAL STUDY;

ANIMAL; BINDING SITES; CYTOSOL; DIGITALIS GLYCOSIDES; DIGITOXIN; DIGOXIN; MALE; PROSTATE; RATS; RECEPTORS, CELL SURFACE; SPIRONOLACTONE; STANOLONE;

EID: 0016693856     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo-97-6-1521     Document Type: Article

References (35)

1. Basinger, G. T., and R. F. Gittis, J U roi 111: 77, 1974.
2. Castro, J. E., H. J. Griffiths, and D. E. Edwards, Br J Surg 58: 485, 1971.
3. Clark, E., JAMA 193: 157, 1965.
4. Stripp, B., R. Menard, N. E. Zampaglione, M. E. Hamrick, and J. R. Gillette, Drug Metab Disposa 1: 216, 1973.
5. Menard, R. H., B. Stripp, and J. R. Gillette, EndocrinologiJ 94: 1628, 1974.
6. Menard, R. H., H. F. Martin, B. Stripp, J. Gillette, and F. C. Bartter, Life Sci 15: 1639, 1974.
7. Steelman, S. L., J. R. Brooks, E. R. Morgan, and D. J. Patanelli, Steroids 14: 449, 1969.
8. LeWitt, E. B., N Engl J Med 248: 316, 1953.
9. Navab, A., L. G. Koss, and J. S. LaDue, JAMA 194: 30, 1965.
10. Brickhardt, D., C. A. Vera, and J. S. LaDue, Ann Int Med 68: 1069, 1968.
11. Stoffer, S. S., K. M. Haynes, N. S. Jiang, and R. J. Ryan JAAM 225: 1643, 1973.
12. Chamness, G. C., K. Huff, and W. L. McGuire, Steroids 25: 627, 1975.
13. Lowry, O. H., N. J. Rosebrough, A. L. Farr, and R. J. Randall, J Biol Chem 193: 265, 1951.
14. Mainwaring, VV. I. P., and R. J. B. King, SteroidCell Interactions, Butterworths, London, 1974, p. 72.
15. Anderson, K. M., and S. Liao, Nature 196: 36, 1968.
16. Mainwaring, W. I. P., J Endocrinol 45: 531, 1969.
17. Baulieu, E. E., and I. Jung, Biochem Biophys Res Commun 38: 599, 1970.
18. Fang, S., and S. Liao, J Biol Chem 246: 16, 1971.
19. Mainwaring, W. I. P., and F. R. Mangan, J Endocrinol 59: 121, 1973.
20. Rennie, P., and N. Bruchovsky, J Biol Chem 247: 1546, 1972.
21. Rodbard, D., and J. E. Lewald, Karolinska Symposia on Research Methods in Reproductive Endocrinology, 2nd Symposium, 1970, p. 79.
22. Rennie, P., and N. Bruchovsky, J Biol Chem 248: 3288, 1973.
23. Wilson, J. D., N Engl J Med 287: 1284, 1972.
24. Mainwaring, W. I. P., Biochem Biophys Res Commun 40: 192, 1970.
25. Doherty, J. E., Ann Intern Med 79: 229, 1973.
26. Venning, G. R., In T. B. Binns (ed.) Absorption and Distribution of Drugs, Livingstone, Edinburgh and London, 1964, p. 150.
27. Mainwaring, W. I. P., and E. J. G. Milroy, J Endocrinol 57: 371, 1973.
28. Bonne, C., and J. P. Raynaud, Mol Cell Endocrinol 2: 59, 1974.
29. Selye, H., M. Krajny, and L. Savoie, Science 164: 842, 1969.
30. Savoie, L., M. Krajny, and B. Kleiman, Cardiologie 54: 287, 1969.
31. Solymoss, B., S. Toth, S. Varga, and H. Selye, Toxicol Appl Phannacol 18: 586, 1971.
32. Solymoss, B., H. G. Classen, and S. Varga, Proc Soc Exp Biol Med 132: 940, 1969.
33. Stripp, B., M. E. Hanrick, N. C. Zampaglione, and J. R. Gillette, J Pharmacol Exp Ther 174: 473, 1970.
34. Castle, M. C., and G. L. Lage, Drug Metab Disposit 1: 590, 1973.
35. Talcott, R. E., and S. J. Stohs, Arch Int Pharmo-codyn Ther 204: 86, 1973.