A new prodiginine (prodigiosin-like) pigment from streptomyces. Antimalarial activity of several prodiginines

The Journal of Antibiotics

Volumn 28, Issue 3, 1975, Pages 194-199

  Gerber, Nancy N ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; PIGMENT; DRUG DERIVATIVE; PRODIGIOSIN;

DEACETYLLAURENOBIOLID; DRUG ANALYSIS; DRUG ISOLATION; DRUG SCREENING; GAS CHROMATOGRAPHY; IN VITRO STUDY; INVERTEBRATE; MALARIA; MASS SPECTROMETRY; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLASMODIUM BERGHEI; STREPTOMYCETACEAE; THEORETICAL STUDY; THIN LAYER CHROMATOGRAPHY; ANIMAL; ARTICLE; CHEMISTRY; ISOLATION AND PURIFICATION; STREPTOMYCES;

ANIMAL; ANTIMALARIALS; CHEMISTRY; MALARIA; MICE; PLASMODIUM BERGHEI; PRODIGIOSIN; STREPTOMYCES;

EID: 0016592043     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.28.194     Document Type: Article

References (12)

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2. Wasserman, H.H.; G.C. Rodgers & D.D. Keith: Metacycloprodigiosin, a tripyrrole pigment from Streptomyces longisporus ruber. J. Amer. Chem. Soc. 91: 1263~1264, 1969.
3. Gerber, N.N.: Minor prodiginine pigments from Actinomadura madurae and Actinomadura pelletieri. J. Heterocycl. Chem. 10: 925~929, 1973.
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5. Castro, A.J.: Antimalarial activity of prodigiosin. Nature (London) 213: 903~904, 1967.
6. Wasserman, H.H.; J.E. Mckeon, L.A. Smith & P. Forgione: Studies on prodigiosin and thebipyrrole precursor. Tetrahedron. Suppl. 8 : 647~662, 1966.
7. Williams, R.H.: The identification of prodigiosin and similar compounds. p. 73. Thesis, Iowa State University, Ph. D., 1965.
8. Rodgers, Jr., G.C.: Studies on bacterial pyrrole pigments. p. 50A. Thesis, Yale University, Ph.D., 1965.
9. Jackman, L.M. & S. Sternhell: Applications of nuclear magnetic resonance spectroscopy inorganic chemistry, 2nd Edition. p. 173. Pergamon Press, 1969.
10. Bhacca, N. S.; D.P. Hollis, L.F. Johnson, & E.A. Pier: High resolution NMR spectra catalog 130, 131, 177 & 278. Varian Associates, 1962.
11. Hearn, W.R.; M.K. Elson, R.H. Williams & J. Medina-Castro: Prodigiosene [5-(2-pyrryl)-2,2′-dipyrrylmethene] and some substituted prodigiosenes. J. Org. Chem. 35: 142~146, 1970.
12. Osdene. T.S.; P.B. Russell & L. Rane: 2,4,7-Triamino-6-ortho-substituted arylpteridines. A new series of potent antimalarial agents. J. Med. Chem. 10: 431~434, 1967.