Substructural Analysis. A Novel Approach to the Problem of Drug Design

Journal of Medicinal Chemistry

Volumn 17, Issue 5, 1974, Pages 533-535

  Cramer, Richard D ^a   Redi, George ^a   Berkoff, Charles E ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; SK&F 37422; SK&F 43248; UNCLASSIFIED DRUG;

DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GUANOSINE TRIPHOSPHATE 4 AZIDOANILIDE; METHODOLOGY; MODEL; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY;

ANTI-INFLAMMATORY AGENTS; BIOPHARMACEUTICS; INFORMATION SYSTEMS; MATHEMATICS; PHARMACEUTICAL PREPARATIONS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0016381211     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00251a014     Document Type: Note

References (11)

1. C. Hansch, Accounts Chem. Res., 2, 232 (1969).
2. S. M. Free and J. W. Wilson, J. Med. Chem., 7, 395 (1964).
3. P. J. Harrison, J. Appl. Stat., 17, 226 (1968).
4. M. F. Lynch, J. M. Harrison, W. G. Town, and J. E. Ash, “Computer Handling of Chemical Structural Information,” American Elsevier, New York, N. Y., 1972, pp 67-95.
5. P. N. Craig and H. M. Ebert, J. Chem. Doc., 9, 141 (1969).
6. D. T. Walz, M. J. DiMartino, and A. Misher, J. Pharmacol. Exp. Ther., 178, 223 (1971).
7. M. Milne, D. Lefkovitz, H. Hill, and R. Powers, J. Chem. Doc., 12, 183 (1972).
8. M. A. T. Rogers, Chem. Ind. (London), 952 (1970).
9. W. T. Wipke, P. Gund, J. G. Verbalis, and T. M. Dyatt, Abstracts, 162nd National Meeting of the American Chemical Society, Washington, D. C., Sept 1971.
10. R. J. Feldmann, S. R. Heller, and C. R. T. Brown, J. Chem. Doc., 12, 234 (1972).
11. E. J. Corey, W. T. Wipke, R. D. Cramer III, and W. J. Howe, J. Amer. Chem. Soc., 94, 431, 440 (1972).