Polyol accumulation in galactosemic and diabetic rats: Control by an aldose reductase inhibitor

Science

Volumn 182, Issue 4117, 1973, Pages 1146-1148

  Dvornik, D ^a   Simard Duquesne, N ^a   Krami, M ^a   Sestanj, K ^a   Gabbay, K H ^b,c   Kinoshita, J H ^d   Varma, S D ^d   Merola, L O ^d  

^a PFIZER INC   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE REDUCTASE; AY 22; FRUCTOSE; GALACTOSE; GLUCOSE; POLYOL; SORBITOL; STREPTOZOCIN; TELE METHYLHISTAMINE; TERT BUTYLOXYCARBONYLTRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; CATARACT; DIABETES MELLITUS; ENZYME INHIBITION; EYE; GALACTOSEMIA; IN VITRO STUDY; LENS; ORAL DRUG ADMINISTRATION; ORGAN CULTURE; PREVENTION; RAT; SCIATIC NERVE; THEORETICAL STUDY;

ACETIC ACIDS; ADMINISTRATION, ORAL; ALCOHOL OXIDOREDUCTASES; ANIMALS; CATARACT; CULTURE TECHNIQUES; DIABETES COMPLICATIONS; DIABETES MELLITUS; DIABETIC NEUROPATHIES; FRUCTOSE; GALACTOSE; GALACTOSEMIAS; GLUCOSE; ISOQUINOLINES; LENS, CRYSTALLINE; RATS; SCIATIC NERVE; SORBITOL; STREPTOZOCIN; SUGAR ALCOHOLS;

EID: 0015887637     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.182.4117.1146     Document Type: Article

References (26)