Induction of cytoplasmic respiratory deficient mutants in yeast by the folic acid analogue, methotrexate - I. Studies on the mechanism of petite induction

MGG Molecular & General Genetics

Volumn 126, Issue 1, 1973, Pages 61-70

  Wintersberger, Ulrike ^a   Hirsch, Jennifer ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; FOLIC ACID; METHOTREXATE; NALIDIXIC ACID;

EXTRACHROMOSOMAL INHERITANCE; HISTOLOGY; LEUCINE H 3; MICROORGANISM; MITOCHONDRION; MUTANT; MUTATION; MUTATION INDUCTION; PROTEIN SYNTHESIS; SACCHAROMYCES CARLSBERGENSIS; SACCHAROMYCES CEREVISIAE; THEORETICAL STUDY;

AEROBIOSIS; ANAEROBIOSIS; CELL DIVISION; COMPARATIVE STUDY; FUNGAL PROTEINS; GALACTOSE; GLUCOSE; GLYCEROL; LEUCINE; METHOTREXATE; MITOCHONDRIA; MUTATION; OXYGEN CONSUMPTION; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; SPECIES SPECIFICITY; SPECTROPHOTOMETRY; TIME FACTORS; TRITIUM;

EID: 0015863888     PISSN: 00268925     EISSN: 16174623     Source Type: Journal    
DOI: 10.1007/BF00333482     Document Type: Article

References (24)

1. Mitochondrial nucleic acids
2. Folic acid antagonists in cancer therapy
3. Formylmethionyl-rRNA dependence of amino acid incorporation in extracts of trimethoprim-treated Escherichia coli
4. Genetic recombination in synchronized cultures of S. cerevisiae
5. The presence of formylmethionyl-tRNA in HeLa cells
6. The petite mutation in yeast. Loss of mitochondrial deoxyribonucleic acid during induction of petites with ethidium bromide
7. Conditions that prevent ñ- induction by eithidum bromide
8. Erzeugung und Untersuchung biochemischer Mangelmutanten
9. Protein measurement with the Folin phenol reagent
10. Protein biosynthesis
11. Effect of trimethorpim on macromolecular synthesis in Escherichia coli
12. Tetrazolium overlay technique for population studies of respiration deficiency in yeast
13. Molecular consequences of ethidium bromide mutagenesis
14. Protein synthesis by yeast promitochondria in vivo
15. Regelung der Synthese von Dihydrofolsäure-Reduktase bei synchronisierten Hefezellen
16. Differentiation between mitochondrial and cytoplasmic protein synthesis in vivo by use of a temperature-sensitive mutant of Saccharomyces cerevisiae
17. Ethidium bromide induced mutation of yeast mitochondria: Complete transformation of cells into respiration deficient non-chromosomal “petites”
18. N-formyl-methionyl transfer RNA in mitochondria from yeast and rat liver
19. Nalidixic acid prevents the induction of yeast cytoplasmic respirationdeficient mutants by intercalating drugs
20. Low temperature and chloramphenicol induction of respiration deficiency in a cold sensitive mutant of Saccharomyces cerevisiae
21. Induction of the cytoplasmic petite mutation in Saccharomyces cerevisiae by the antibacterial antibiotics erythromycin and chloramphenicol