Biochemical basis for analgesic activity of morphine-6-glucuronide-I. Penetration of morphine-6-glucuronide in the brain of rats

Biochemical Pharmacology

Volumn 22, Issue 12, 1973, Pages 1423-1430

  Yoshimura, Hidetoshi ^a   Îda, Seiu ^a   Oguri, Kazuta ^a   Tsukamoto, Hisao ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; GLUCURONIDE; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; NARCOTIC ANALGESIC AGENT;

BLOOD BRAIN BARRIER; BRAIN; CONJUGATION; DRUG METABOLISM; METABOLISM; MORPHINE C 14; MORPHINE GLUCURONIDE; MORPHINE GLUCURONIDE C 14; RAT; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY;

ANIMAL; BLOOD PROTEINS; BRAIN; CARBON ISOTOPES; CHROMATOGRAPHY, DEAE-CELLULOSE; CHROMATOGRAPHY, THIN LAYER; GLUCURONATES; LIVER; MALE; MORPHINE; RATS; TRITIUM;

EID: 0015800923     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(73)90320-1     Document Type: Article

References (15)

1. Metabolism of drugs—LXII
2. On the Structure of Morphine-6-glucuronide in a Solid State
3. Notes- Morphine-N-Methyl-C14
4. Uptake of morphine-3-glucuronide by choroid plexuses in vitro