Similarities of the anti-tumour actions of endotoxin, lipid A and double-stranded RNA

British Journal of Cancer

Volumn 27, Issue 5, 1973, Pages 370-389

  Parr, I ^a   Wheeler, E ^a   Alexander, P ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ENDOTOXIN; LIPID; PHENOXYBENZAMINE; RNA; VIRUS RNA;

ANIMAL; ARTICLE; CANCER TRANSPLANTATION; EXPERIMENTAL NEOPLASM; FIBROSARCOMA; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOMA; MOUSE; MOUSE STRAIN; PERITONEUM TUMOR; SKIN TUMOR; STRUCTURE ACTIVITY RELATION;

ANIMAL; ANTINEOPLASTIC AGENTS; ENDOTOXINS; FIBROSARCOMA; IMMUNOSUPPRESSION; LIPIDS; LYMPHOMA; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, INBRED DBA; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; PERITONEAL NEOPLASMS; PHENOXYBENZAMINE; RNA; RNA, VIRAL; SKIN NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0015619859     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1973.45     Document Type: Article

References (29)

1. Alexander, P. & Evans, R. (1971) Endotoxin and Double Stranded RNA render Macrophages cytotoxic. Nature, New Biol., 232, 76.
2. Andervont, H. B. (1936) The Reaction of Mice and of various Mouse Tumours to the Injection of Bacterial Products. Am. J. Cancer, 27, 77.
3. Busch, (1866) Verhandlungen arztlicher Gesell-schaften. Klin. Wschr., 3, 245.
4. Dröge, W., Lehmann, V., Lüderitz, O. & West-phal, O. (1970) Structural Investigations on the 2-keto-3-deoxyoctonate Region of Lipopolysac-charides. Eur. J. Biochem., 14, 175.
5. Eckenhoff, J. E., Cooperman, L. H. (1965) The Clinical Application of Phenoxybenzamine in Shock and Vasoconstrictive states. Surgery, Oynec. Obstet., 121, 483.
6. Evans, R. (1972) Macrophages in Syngeneic Animal Tumours. Transplantation, 14, 468.
7. Fischer, J. C., Cooperband, S. R. & Mannick, J. A. (1972) The Effect of Polyinosinic-poly-cytidylic acid on the Immune Response of Mice to Antigenically Distinct Tumours. Cancer Res., 32, 889.
8. Galanos, C., Rietschel, E. T., Lüderitz, O. & Westphal, O. (1971) Interaction of Lipopoly-saccharides and Lipid A with Complement. Eur. J. Biochem., 19, 143.
9. Gmeiner, J., Lüderitz, O. & Westphal, O. (1969) Biochemical Studies on Lipopolysaccharides of Salmonella R mutants. 6. Investigations on the structure of the Lipid A Component. Eur. J. Biochem., 7, 370.
10. Good, R. A. & Thomas, L. (1953) Studies on the Generalized Shwartzman Reaction. IV. Prevention of the Local and Generalized Shwartzman Reactions with Heparin. J. exp. Med., 97, 871.
11. Halpern, B. N., Biozzi, G., Stiffel, C. & Moulton, D. (1959) Corrélation entre l’activité phagocytaire du systeme reticulo-endothelial et la production d’anticorps antibacteriens. C.r. Soc. Biol., 153, 919.
12. Halpern, B. N., Biozzi, G., Stiffel, C. & Moulton, D. (1966) Inhibition of Tumour Growth by Administration of killed Corynebacterium parvum. Nature, Lond., 212, 853.
13. Hibbs, J. B., Jr., Lambert, L. H., Jr. & Remington, J. S. (1971) Tumour Resistance conferred by Intracellular Protozoa. J. clin. Invest., 50, 45a.
14. Hibbs, J. B., Jr., Lambert, L. H., Jr. & Remington, J. S. (1972) Possible Role of Macrophage mediated Nonspecific Cytotoxicity in Tumour Resistance. Nature, New Biol., 235, 48.
15. Hilleman, M. R. (1970) Double-stranded RNAs (Poly I: C) in the Prevention of Viral Infections. Archs intern. Med., 126, 109.
16. Levy, E. Z., North, W. C. & Wells, J. A. (1954) Modification of Traumatic Shock by Adrenergic Blocking Agents. J. Pharmac. exp. Ther., 112.151.
17. Levy, H. B., Law, L. W. & Rabson, A. S. (1969) Inhibition of Tumour Growth by Polyinosinic-polycytidylic acid. Proc. natn. Acad. Sci., 62, 357.
18. Levy, H. B. (1970) Interferon and Interferon inducers in the Treatment of Malignancies. Archs intern. Med., 126, 78.
19. Levy, M. N. & Blattberg, B. (1964) In Shock. Ed. S. G. Hershey. Boston: Little, Brown and Co.
20. Lüderitz, O. (1970) Recent Results on the Biochemistry of the Cell Wall. Lipopolysaccharides of Salmonella Bacteria. Angew. Chem., 9, 649.
21. Mathé, G., Pouillart, P. & Lapeyraque, F. (1969) Active Immunotherapy of LI210 Leukaemia Applied after the Graft of Tumour Cells. Br. J. Cancer, 23, 814.
22. Nauts, H. C., Fowler, G. A. & Bogatko, F. H. (1953) A Review of the Influence of Bacterial Infection and of Bacterial Products (Coley’s Toxins) on Malignant Tumours in Man. Acta med. scand., 45, Suppl. No. 276.
23. Old, L. J., Benacerraf, B., Clarke, D. A., Carswell, E. A. & Stockert, E. (1961) The Role of the Reticulo-endothelial System in the Host Reaction to Neoplasia. Cancer Res., 21, 1281.
24. Parr, I. (1972) Response of Syngeneic Murine Lymphomata to Immunotherapy in Relation to Antigenicity of the Tumour. Br. J. Cancer, 26, 174.
25. Planterose, D. N., Birch, P. J., Pilch, D. J. F. & Sharpe, T. J. (1970) Antiviral Activity of dsRNA and virus-like Particles from Penicillium Stoloni-ferum. Nature, Lond., 227, 504.
26. Pilch, D. J. F. & Planterose, D. N. (1971) Effects on Friend Disease of double-stranded RNA of Fungal Origin. J. gen. Virol., 10, 155.
27. Shwartzman, G. (1937) Phenomenon of Local Tissue Reactivity and its Immunological, Pathological and Clinical Significance. New York: P. B. Hoeber Inc. p. 461.
28. Sutthiwan, P., Shorter, R. G., Hallenbeck, G. A. & Elveback, L. R. (1969) Comparison of Rabbit Anti-mouse thymus sera Produced after Different Numbers of Injections of Lymphoid Cells. Transplantation, 8, 249.
29. Westphal, O. & Lüderitz, O. (1954) Chemische Erforschung von Lipopolysacchariden gramnega-tiver Bakterien. Angew. Chem., 66, 407