Bioavailability, clinical effectiveness, and the public interest

Pharmacology

Volumn 8, Issue 1-3, 1972, Pages 33-43

  Levy, G ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

ARTICLE; COST; DOSE RESPONSE; DRUG DOSAGE FORM; DRUG INDUSTRY; DRUG THERAPY; HUMAN; INTESTINE ABSORPTION; METABOLISM; PHARMACEUTICS; PHARMACOLOGY; STANDARD;

BIOPHARMACEUTICS; COSTS AND COST ANALYSIS; DOSAGE FORMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INDUSTRY; DRUG THERAPY; HUMAN; INTESTINAL ABSORPTION; PHARMACEUTICAL PREPARATIONS; PHARMACOLOGY;

EID: 0015464247     PISSN: 00317012     EISSN: 14230313     Source Type: Journal    
DOI: 10.1159/000136325     Document Type: Article

References (19)

1. Levy, G.: Kinetics of pharmacologic effects. Clin. Pharmacol. Ther. 7: 362 (1966).
2. Nagashima, R.; OReilly, R.A., and Levy, G.: Kinetics of pharmacologic effects in man. The anticoagulant action of warfarin. Clin. Pharmacol. Ther. 10: 22 (1969).
3. Gibaldi, M.; Levy, G., and Weintraub, H.: Drug distribution and pharmacologic effects. Clin. Pharmacol. Ther. 12: 734 (1971).
4. Levy, G. and Gibaldi, M.: Pharmacokinetics of drug action. Ann. Rev. Pharmacol. 12: 85 (1972).
5. Gibaldi, M.; Levy, G., and Hayton, W.L.: Kinetics of tubocurarine elimination and neuromuscular blocking effect in man. Anesthesiology 36: 213 (1972).
6. Levy, G.; Gibaldi, M., and Jusko, W.J.: Multicompartment pharmacokinetic models and pharmacologic effects. J. pharm. Sci. 58: 422 (1969).
7. Levy, G.: Dose dependent effects in pharmacokinetics; in Importance of fundamental principles in drug evaluation, pp. 141-172 (Raven Press, New York 1968).
8. Levy, G.: Drug biotransformation interactions in man: nonnarcotic analgesics. Ann. N.Y. Acad. Sci. 179: 32(1971).
9. Tsuchiya, T. and Levy, G.: Relationship between dose and plateau levels of drugs eliminated by parallel first-order and capacity-limited kinetics. J. pharm. Sci. 61: 541 (1972).
10. Paulus, H.E.; Siegel, M.; Mongan, E.; Okun, R., and Calabro, J.J.: Variations of serum concentrations and half-life of salicylate in patients with rheumatoid arthritis. Arthritis Rheum. 14: 527 (1971).
11. Calabro, J.J. and Marchesano, J.M.: Fever associated with juvenile rheumatoid arthritis. New Engl. J. Med. 276: 11 (1967).
12. Levy, G. and Hollister, L. E.: Failure of USP disintegration test to assess physiologic availability of enteric-coated tablets. N.Y. St. J. Med. 64: 3002 (1964).
13. Emerson, D.N.: Potassium therapy and gastro-intestinal lesions. Rhode Isl. med. J. 53: 378 (1970).
14. Levy, G. and Leonards, J.R.: The biopharmaceutics of aspirin-induced gastrointestinal blood loss. Farmaceutiskt Notisbl. 80: 106 (1971).
15. Levy, G. and Leonards, J.R.: Urine pH and salicylate therapy. J. amer. med. Ass. 217: 81 (1971).
16. Vesell, E.S. and Passananti, G.T.: Utility of clinical determinations of drug concentrations in biological fluids. Clin. Chem. 17: 851 (1971).
17. Levy, G.: The therapeutic implications of brand interchange. Amer. J. Hosp. Pharmacy 17: 756 (1960).
18. Levy, G. and Nelson, E.: Pharmaceutical formulation and therapeutic efficacy. J. amer. med. Ass. 177: 689 (1961).
19. Levy, G. and Nelson, E.: USP and NF standards, FDA regulations and the quality of drugs. N.Y. St. J. Med. 61: 23 (1961).