the Preparation of Guanidine Hydrochloride

Methods in Enzymology

Volumn 26, Issue C, 1972, Pages 43-50

  Nozaki, Yasuhiko ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GUANIDINE DERIVATIVE;

ARTICLE; CRYSTALLIZATION; ISOLATION AND PURIFICATION; KINETICS; MATHEMATICS; PH; PROTEIN DENATURATION; SOLUBILITY; TECHNIQUE; TEMPERATURE; ULTRAVIOLET SPECTROPHOTOMETRY;

CRYSTALLIZATION; EVALUATION STUDIES; GUANIDINES; HYDROGEN-ION CONCENTRATION; KINETICS; MATHEMATICS; METHODS; PROTEIN DENATURATION; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TEMPERATURE;

EID: 0015438810     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/S0076-6879(72)26005-0     Document Type: Article

References (14)

1. Anson, M.L., J. Gen. Physiol., 24, 1946, 399.
2. Wong, K.-P., Boxby, R, Tanford, C, Anal. Biochem., 40, 1971, 459.
3. Engelbrecht, R.M., Mosely, H.E., Donahue, W.F., Rolington, W.R., Anal. Chem., 29, 1957, 579.
4. Fridovich, I, Biochemistry, 4, 1965, 1098.
5. Fridovich, I, J. Biol. Chem., 240, 1965, 2491.
6. Nozaki, Y, Tanford, C, J. Amer. Chem. Soc., 89, 1967, 736.
7. Y. Nozaki, unpublished observation. This compound shows an absorption maximum at 272 nm at acid to neutral pH and an approximate pK of 9.6. It seems to be derived from one of the impurities present in GuHCl samples, since its formation levels off within several days, unlike biguanide formation which continues as long as a GuHCl solution is kept alkaline.
8. Kolthoff, I.M., Anastasi, A, Stricks, W, Tan, B.H., Deshmukh, G.S., J. Amer. Chem. Soc., 79, 1957, 5102.
9. Costa, G.W., Hirt, R.C., Salley, D.J., J. Chem. Phys., 18, 1950, 434.
10. Hirt, R.C., Schmitt, R.G., Spectrochim. Acta, 12, 1958, 127.
11. Tanford, C, Shedlovsky, T, (eds.) Electrochemistry in Biology and Medicine, 1955, Wiley, New York.
12. Powell, J, Miller, M, J. Chem. Educ., 34, 1957, 330.
13. Y. Nozaki and C. Tanford, see Vol. XI, p. 715.
14. Based on the procedure given by Theilacker, Z, Z. Kristallog., 76, 1931, 303.