Rapid induction of bladder cancer in rats with N-methyl-N-nitrosourea I. Histology

Chemico-Biological Interactions

Volumn 5, Issue 2, 1972, Pages 139-152

  Hicks, R M ^a   St J Wakefield, J ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NITROSO DERIVATIVE; NITROSOUREA DERIVATIVE; UREA;

ANIMAL; ARTICLE; BLADDER; BLADDER TUMOR; EPITHELIUM; EXPERIMENTAL NEOPLASM; FEMALE; HYPERPLASIA; IATROGENIC DISEASE; MALE; NECROSIS; PAPILLOMA; PATHOLOGY; RAT;

ANIMAL; BLADDER; BLADDER NEOPLASMS; EPITHELIUM; FEMALE; HYPERPLASIA; MALE; NECROSIS; NEOPLASMS, EXPERIMENTAL; NITROSO COMPOUNDS; NITROSOUREA COMPOUNDS; PAPILLOMA; RATS; UREA;

EID: 0015373340     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2797(72)90040-3     Document Type: Article

References (33)

1. Carcinogenic nitroso compounds
2. Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-Ratten
3. Erzeugung von Blasenkrebs an Ratten mit N,N-Dibutylnitrosamin
4. Selektive Erzeugung von Blasenkrebs an Ratten durch Dibutyl- und N-Butyl-N-butanol(4)-nitrosamin
5. Erzeugung von Krebs durch einmalige Dosis von Methylnitrosoharnstoff und verschiedenen Dialkylnitrosaminen an Ratten
6. The induction of tumours in the rat by a single oral dose of N-nitrosomethylurea
7. Die Induktion von Hirn- und Rückenmarktumoren bei Kaninchen mit N-Methyl-N-nitrosoharnstoff
8. Nitrosamine-induced carcinogenesis
9. The rate of breakdown of methyl methanesulphonate, dimethyl sulphate and N-methyl-N-nitrosourea in the rat
10. Cyclophosphamide and urinary bladder toxicity
11. A light and electron microscope study of the effects of a single dose of cyclophosphamide on various organs in the rat, I. The urinary bladder
12. Induction of bladder hyperplasia in rats after a single dose of cyclophosphamide
13. Repair of rat urinary bladder epithelium following injury by cyclophosphamide
14. Studies on the mechanism of action of cytoxan. Evidence of activation in vivo and in vitro
15. The use of rat bladder pouches to elucidate the mode of action of a chemical which induces hyperplasia in the bladder epithelium
16. Early changes in the fine structure of rat bladder epithelium induced by 4-ethylsulphonylnaphthalene-1-sulphonamide
17. Cancer of the urinary tract
18. Erzeugung von Magenkrebs durch Nitrosamide an Ratten
19. Induction of tumour in mice with H,N-bis(2-chloro-ethyl),N,N-O-propylene phosphoric acid ester diamide (cyclophosphamide)
20. A sulphonamide derivative which induces urinary tract epithelial hyperplasia and carcinomas of the bladder epithelium in the mouse
21. The induction of tumours of the mouse bladder epithelium by 4-ethylsulphonylnaphthalene-1-sulphonamide
22. Enhancement of tumorigenesis in the urinary bladder of rats by neonatal administration of 2-acetylaminofluorene
23. 6 containing N-2-fluorenylacetamide after single dose of cyclophosphamide
24. Occupational tumours of the bladder
25. Histogenesis of urinary bladder tumors induced by N-butyl-N(4-hydroxybutyl)-nitrosamine in rats
26. Induction of bladder tumours in mice with dibutylnitrosamine
27. Effect of dl-tryptophan on tumorigenesis in the urinary bladder and liver of rats treated with N-nitrosodibutylamine
28. The production of carcinoma of the urinary bladder in rats by feeding N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide
29. Pathogenesis histology and transplantability of urinary bladder carcinomas induced in albino rats by oral administration of N-(4-(5-Nitro-2-furyl)-2-thiazolyl) formamide
30. Interaction of the carcinogenic N-methylnitrosourethane with sulphhydryl groups
31. Prevention by cysteamine of the inhibitory effect of N-nitrosodialkylamines on incorporation of amino acids in rat liver