Psychosedative Agents. 2. 8-(4-Substituted 1-Piperazinylalky1)-8-azaspiro[4.5]decane-7, 9-diones

Journal of Medicinal Chemistry

Volumn 15, Issue 5, 1972, Pages 477-479

  Wu, Yao Hua ^a   Rayburn, J W ^a   Allen, L E ^b   Ferguson, H C ^b   Kissel, J W ^b  

^a Department of Chemical Research ^*  (United States)

^b Mead Johnson Nutritionals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HETEROCYCLIC COMPOUND; HEXOBARBITAL; KETONE; PIPERAZINE DERIVATIVE; SPIRO COMPOUND; TRANQUILIZER;

ANIMAL; ANIMAL BEHAVIOR; ARTICLE; AVOIDANCE BEHAVIOR; DRUG EFFECT; DRUG POTENTIATION; ESCAPE BEHAVIOR; MOTOR ACTIVITY; MOUSE; RAT; SYNTHESIS;

ANIMAL; AVOIDANCE LEARNING; AZA COMPOUNDS; BEHAVIOR, ANIMAL; DRUG SYNERGISM; ESCAPE REACTION; HEXOBARBITAL; KETONES; MICE; MOTOR ACTIVITY; PIPERAZINES; RATS; SPIRO COMPOUNDS; TRANQUILIZING AGENTS;

EID: 0015341695     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00275a009     Document Type: Article

References (8)

1. Y. H. Wu, K. R. Smith, J. W. Rayburn, and J. W. Kissel, J. Med. Chem., 12, 876 (1969).
2. L. E. Allen, A. J. Mueller, and J. W. Kissel, Pharmacologist, 11, 247 (1969).
3. G. Illuminati, Advan. Heterocycl. Chem., 3, 285 (1964).
4. J. W. Kissel, Science, 139, 1224 (1963).
5. N. W. Dunham and T. S. Miya, J. Amer. Pharm. Ass. Sci. Ed., 46, 208 (1957).
6. P. A. J. Janssen, U. S. Patent 2, 985, 657 (May 23, 1961);
7. Chem. Abstr., 57, 11208h (1962).
8. R. P. Mull, R. H. Mizzoni, M. R. Dapero, and M. E. Egbert, J. Med. Chem., 5, 944 (1962).