Haloperidol, clopenthixol, and chlorpromazine in chronic schizophrenia: Chemically unrelated antipsychotics as therapeutic alternatives

Journal of Nervous and Mental Disease

Volumn 154, Issue 1, 1972, Pages 31-42

  Skrafetinides, E A ^a   Collins, S ^a   Clark, M L ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; BILIRUBIN; CHLORPROMAZINE; CHOLESTEROL; CLOPENTHIXOL; HALOPERIDOL; PIPERAZINE DERIVATIVE; PLACEBO; TRANQUILIZER; XANTHENE DERIVATIVE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; BLOOD; BLOOD CELL COUNT; BLOOD PRESSURE; BODY TEMPERATURE; BODY WEIGHT; CHRONIC DISEASE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; EXTRAPYRAMIDAL SYSTEM; FEMALE; HEMATOCRIT; HUMAN; LIVER; MALE; PSYCHOLOGIC TEST; RATING SCALE; SCHIZOPHRENIA; TOXIC HEPATITIS; UREA NITROGEN BLOOD LEVEL;

ADULT; ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANALYSIS OF VARIANCE; BILIRUBIN; BLOOD CELL COUNT; BLOOD PRESSURE; BLOOD UREA NITROGEN; BODY TEMPERATURE; BODY WEIGHT; CHLORPROMAZINE; CHOLESTEROL; CHRONIC DISEASE; CLINICAL TRIALS; CLOPENTHIXOL; COMPARATIVE STUDY; EXTRAPYRAMIDAL TRACTS; FEMALE; HALOPERIDOL; HEMATOCRIT; HEPATITIS, TOXIC; HUMAN; LIVER; MALE; MIDDLE AGE; PIPERAZINES; PLACEBOS; PSYCHIATRIC STATUS RATING SCALES; PSYCHOLOGICAL TESTS; SCHIZOPHRENIA; TRANQUILIZING AGENTS; XANTHENES;

EID: 0015264743     PISSN: 00223018     EISSN: 1539736X     Source Type: Journal    
DOI: 10.1097/00005053-197201000-00005     Document Type: Article

References (17)

1. Ayd, F. J. Current status of clopenthixol. Int. Drug Ther. Newsletter 4: 5-8, 1969.
2. Ban, T. A. and Lchmann, H. E. Efficacy of haloperidol in drug refractory patients. Int.J. Neuropsychiat. 3: 78-83, 1967.
3. Clark, M. L., Braun, G. A., Hewson, J. R., Sorafotinides, E. A, Colmore, J. P. and Rahhal, D. K. Trifluperidol and cholesterol in man. Clin. Pharmacol. Ther. 9: 333-340, 1968.
4. Clark, M. L., Ray, T. S., Paredes, A., Costiloe, J. P., Chappell, J. S., Hagans, J. A. and Wolf, S. Chlorpromazine in chronic schizophrenic women: I. Experimental design and effects at maximum point of treatment. Psychopharmacologia 2: 107-136, 1961.
5. Clark, M. L., Ray, T. S., Paredes, A., Ragland, R. E., Costiloe, J. P., Smith, C. W. and Wolf, S. Chlorpromazine in women with chronic schizophrenia. The effect oncholesterol levels and cholesterol-behavior relationships. Psychosom. Med. 29: 634-642, 1967.
6. Crane, G. E. A review of clinical literature on haloperidol. Int. J. Neuropsychiat. 8: 110-123, 1967.
7. Goldberg, S. C. Prediction of response to antipsychotic drugs. Presented at the American College of Neuropsychopharma-cology. San Juan, Puerto Rico, December, 1967.
8. Gonier, T., Schiele, B. C. and Vestre, N. D. A comparison of haloperidol and thioridazine HC1 in chronic treatment-resistant schizophrenics. Physicians' Drug Manual 2: 47-54, 1970
9. Ilonigfeld, G. and Klett, C. The nurse's observation scale for inpatients evaluation (NOSIE). A new scale for measuring improvement in chronic schizophrenia. J. Clin. Psychol. 21: 65-71, 1965.
10. Janssen, P. A. J. The pharmacology of haloperidol. Int. J. Neuropsychiat. 3: 10-18, 1967.
11. Lapolla, A. Clinical efficacy of haloperidol in chronic psychiatric patients. Int. J. Neuropsychiat. 3: 68-74, 1967.
12. Merlis, S. Thioxanthenes: Discussion of the clinical investigation papers. In The Thioxanthenes, pp. 113-116. Karger, New York, 1969.
13. Overall, J. E. and Gorham, D. R. Brief psychiatric rating scale. Psychol. Rep. 10: 799-822, 1962.
14. Schiele, B. C. Studies with clopenthixol and thiothixene. In The Thioxanthenes, pp. 100-105. Karger, New York, 1969.
15. Simpson, G. M., Angus, J. W. S. and Igbal, I. The effect of clopenthixol in chronic schizophrenia. Curr. Ther. Res. 8: 85, 1966.
16. Venables, P. H.: A short scale for rating "activity-withdrawal" in schizophrenics. J. Ment. Sci. 103: 197-199, 1957.
17. Venables, P. H. and O'Connor, N. A short scale for rating paranoid schizophrenia. J. Ment. Sci. 105: 815-818, 1959.