In vitro induction of lysosomal enzymes by phagocytosis

Journal of Experimental Medicine

Volumn 131, Issue 6, 1970, Pages 1239-1260

  Axline, Stanton G ^a,b   Cohn, Zanvil A ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE; BETA GLUCURONIDASE; CATHEPSIN; POLYSTYRENE DERIVATIVE; POLYVINYL DERIVATIVE; PROTEIN; PUROMYCIN; STARCH; TOLUENE;

ANIMAL; ARTICLE; BIOSYNTHESIS; DRUG EFFECT; ELECTRON MICROSCOPY; ENZYME INDUCTION; ENZYMOLOGY; ERYTHROCYTE; LYSOSOME; MACROPHAGE; MOUSE; MYCOBACTERIUM BOVIS; PHAGOCYTOSIS; PINOCYTOSIS; SHEEP; TISSUE CULTURE;

ACID PHOSPHATASE; ANIMAL; CATHEPSINS; ENZYME INDUCTION; ERYTHROCYTES; GLUCURONIDASE; LYSOSOMES; MACROPHAGES; MICE; MICROSCOPY, ELECTRON; MYCOBACTERIUM BOVIS; PHAGOCYTOSIS; PINOCYTOSIS; POLYSTYRENES; POLYVINYLS; PROTEINS; PUROMYCIN; SHEEP; STARCH; TISSUE CULTURE; TOLUENE;

EID: 0014800620     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.131.6.1239     Document Type: Article

References (21)

1. Cohn, Z. A., and B. Benson, 1965. The in vitro differentiation of mononuclear phagocytes. III. The reversibility of granule and hydrolytic enzyme formation and turnover of granule constituents. J. Exp. Med. 122: 455.
2. Cohn, Z. A., M. E. Fedorko, and J. G. Hirsch. 1966. The in vitro differentiation of mononuclear phagocytes. V. The formation of macrophage lysosomes. J. Exp. Med. 123: 757.
3. Cohn, Z. A., and B. Benson. 1965. The differentiation of mononuclear phagocytes: morphology, cytochemistry, and biochemistry. J. Exp. Med. 121: 153.
4. Hirsch, J. G., and M. E. Fedorko. 1968. Ultrastructure of human leukocytes after simultaneous fixation with glutaraldehyde and osmium tetroxide and "postfixation" in uranyl acetate. J. Cell Biol. 38: 615.
5. Gomori, G. 1952. Microscopic Histochemistry. The University of Chicago Press, Chicago. 193.
6. Cohn, Z. A., and E. Wiener, 1963. The particulate hydrolases of macrophages. I. Comparative enzymology, isolation, and properties. J. Exp. Med. 118: 99.
7. Axline, S. G. 1968. Isozymes of acid phosphatase in normal and Calmette-Guerin bacillus-induced rabbit alveolar macrophages. J. Exp. Med. 128: 1031.
8. Lowry, O. H., N. J. Rosenbrough, A. L. Farr, and R. J. Randall. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193: 265.
9. McCready, R. M., J. Guggolz, V. Silviera, and S. Owens. 1950. Determination of starch and amylase in vegetables. Anal. Chem. 22: 1156.
10. Cohn, Z. A., and B. Benson. 1965. The in vitro differentiation of mononuclear phagocytes. II. The influence of serum on granule formation, hydrolase production, and pinocytosis. J. Exp. Med. 121: 835.
11. Cohn, Z. A., and B. Benson. 1965. The in vitro differentiation of mononuclear phagocytes. I. The influence of inhibitors and the results of autoradiography. J. Exp. Med. 121: 279.
12. Cohn, Z. A. 1966. The regulation of pinocytosis in mouse macrophages. I. Metabolic requirements as defined by the use of inhibitors. J. Exp. Med. 124: 557.
13. Meijer, A. E., and R. G. J. Willinghagen. 1963. The activity of glucose-6-phosphatase, adenosine triphosphatase, succinic dehydrogenase, and acid phosphatase after dextran or polyvinylpyrrolidone uptake by liver in vivo. Biochem. Pharmacol. 12: 973.
14. Goldberg, L. 1960. Biochemical changes in the tissues of animals injected with iron; acid phosphatase and other enzymes. Biochem. J. 77: 252.
15. Khoo, K. K., and G. B. Mackaness, 1964. Macrophage proliferation in relation to acquired cellular resistance. Aust. J. Exp. Biol. Med. Sci. 42: 707.
16. deDuve, C., and R. Wattiaux. 1966. Functions of lysosomes. Annu. Rev. Physiol. 28: 435.
17. Maack, T. 1968. Changes in the activity of acid hydrolases during renal reabsorption of lysozyme. J. Cell Biol. 35: 268.
18. Shimke, R. T., E. W. Sweeney, and C. M. Berlin, 1965. The role of synthesis and degradation in the control of rat liver tryptophan pyrrolase. J. Biol. Chem. 240: 322.
19. Drysdale, J. W., and H. N. Munro, 1966. Regulation of synthesis and turnover of ferritin in rat liver. J. Biol. Chem. 241: 3630.
20. Ehrenreich, B. A., and Z. A. Cohn, 1969. The fate of peptides pinocytosed by macrophages in vitro. J. Exp. Med. 129: 227.
21. Munro, H. N. 1968. Role of amino acid supply in regulating ribosome function. Fed. Proc. 27: 1231.