DNA toposiomerase i inhibitor by Streptomyces sp. 7489

Korean Journal of Applied Microbiology and Biotechnology

Volumn 24, Issue 1, 1996, Pages 101-104

  Lee, Dong Sun ^a   Ha, Sang Chul ^b   Lee, Sang Yong ^a   Kim, Jong Guk ^a   Hong, Soon Duck ^a  

^a Kyungpook National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Dibutyl phthalate; DNA topoisomerase I inhibitor; Streptomyces melanosporofaciens 7489

Indexed keywords

EID: 0013612929     PISSN: 02572389     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Wang, J.C. 1985. DNA Topoisomerase. Ann. Rev. Biochem. 54: 665-695.
2. D'Arpa, P. and L.F. Liu. 1989. Topoisomerase-targeting antitumor drugs. Biochem. Biophys. Acta. 989: 163-177.
3. Liu, L.F. 1989. DNA Topoisomerase poisons as antitumor drug. Annu. Rev. Biochem. 58: 351-375.
4. Yoshinori Yamashita, Sho-zou Kawada, N. Fujii, and H. Nakano. 1991. Induction of mammalian DNA Topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from Fungas. Biochemistry 30: 5838-5845.
5. Schneider, E., Y.H. Hslang and L.F. Liu. 1990. DNA Topoisomerase as anticancer drug targets. Adv. Phannacol. 21: 149-183.
6. Dalica, K. and R.J. Franco. 1988. Inhibitors of DNA Topoisomerase. Biochemistry 27: 2253-2258.
7. Giovanella, B.C., J.S. Stehlin, M.E. Wall, M.C. Wani, A.W. Nicholas, L.F. Liu, R. Silber and M. Potmesil. 1989. DNA Topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 246: 1046-1048.
8. Hertzberg, R.P., M J. Caranfa, K.G. Holden, D.R. Jakas, G. Gallagher, M.R. Mattern, S.M. Mong, J.O. Bartus, R.K. Johnson and W.D. Kingsbury. 1989. Modification of the hydroxyl lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity. J. Med. Chem. 32: 715-720.
9. Lee D.S., S.C. Ha, W.C. Shin, T.H. Park, J.G. Kim and S.D. Hong. 1995. Numerical identification of an actinomycetes strain producing an antitumor antibiotic with inhibitory activity against DNA topoisomerase I. Kor. J. Appl. Microbiol. Biotechnol. 23: 123-130.
10. Astrio Rex and Luis Arrieta. 1973. Chilaphylin: A new Antibiotic produced by Streptomyces melanosporofaciens strain chilea. The Journal of Antibiotics 26(3): 126-130.
11. Hammann, P. and G. Kretzschmar. 1990. Secondary metabolites by chemical screening, 6. Cleavage of elaiophylin and transformation into a spiroketal building block. Tetrahedron 46: 5609-5616.
12. Arcamone, F.M., C. Bertazolli, M. Ghlone and T. Scotti. 1959. Melanosporin and elaiophylin, new antibiotics from Streptomyces melanosporus. Gion Microbiol. 7: 207-216.
13. Kim, S.K., S.S. Kim, K.S. Kim, Y.R. Chung and C.H. Kim. 1991. New antibiotics produced by Streptomyces melanosporofacience II. Antimicrobial activities and isolation, purification and structure determination of the active compound. Kor. J. Appl. Microbiol. Biotechnol. 19: 235-241.
14. Savard M.E., J.D. Miller, L.A. blois, K.A. Seifert, and RA. Samson. 1994. Secondary metabolites of Penicillium bilaii strain pB-50. Mycopathologia 127(1): 19-27.
15. Kageyama K., Y. Onoyama, T. Nokajima, S. Otani, I. Yano, H.Hotta, Y.I. Matsui, H. Kogawa and N. Miwa. 1994. DNA synthesis inhibitor and transmembrane permeation into tumor cells by various dialkyl phthalate upon hyperthemia. Anticancer Res. 14(6B): 2769-2772.