Novel synthesis of prostaglandin-E2 involving regioselective ring opening of a 2,3-endo-epoxybicyclo[3.2.0]heptan-6-one acetal with a mixed organocuprate reagent

Journal of the Chemical Society, Chemical Communications

Volumn , Issue 15, 1978, Pages 662-664

  Newton, Roger F ^a   Howard, Colin C ^a   Reynolds, Derek P ^a   Wadsworth, Alan H ^a   Crossland, Noelle M ^b   Roberts, Stanley M ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b UNIVERSITY OF SALFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0013607752     PISSN: 00224936     EISSN: None     Source Type: Journal    
DOI: 10.1039/C39780000662     Document Type: Article

References (8)

1. Z. Grudzinski and S. M. Roberts, J.C.S. Perkin I, 1975, 1767.
2. M. J. Dimsdale, R. F. Newton, D. K. Rainey, C. F. Webb, T. V. Lee, and S. M. Roberts, J.C.S. Chem. Comm., 1977, 716.
3. N. M. Crossland, S. M. Roberts, and R. F. Newton, J.C.S. Chem. Comm., 1978, preceding communication.
4. E. J. Corey and R. Noyori, Tetrahedron Letters, 1970, 311.
5. E. J. Corey, K. C. Nicolaou, and D. J. Beames Tetrahedron Letters, 1974, 2439.
6. S. M. Ali, N. M. Crossland, S. M. Roberts, and R. F. Newton, J.C.S. Perkin I, in the press.
7. R. D. Acker, Tetrahedron Letters, 1977, 3407.
8. N. M. Crossland, S. M. Roberts, R. F. Newton, and C. F. Webb, J.C.S. Chem. Comm., 1978, 660 (accompanying communication).