Progestogen-androgen combination: Results of Indonesian clinical trials

Medical Journal of Indonesia

Volumn 6, Issue 1, 1997, Pages 15-24

  Arsyad, Kiagus Muhammad ^a  

^a SRIWIJAYA UNIVERSITY   (Indonesia)

Author keywords

Indonesian men; Male hormonal contraceptives; Progestogen testosterone regimen

Indexed keywords

MEDROXYPROGESTERONE ACETATE; TESTOSTERONE ENANTATE;

ACNE; ARTICLE; AZOOSPERMIA; CLINICAL TRIAL (TOPIC); FOLLITROPIN BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HUMAN; LIBIDO; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE FERTILITY; MULTICENTER STUDY (TOPIC); SEMEN ANALYSIS; TESTOSTERONE BLOOD LEVEL; WEIGHT GAIN;

EID: 0013566164     PISSN: 08531773     EISSN: 22528083     Source Type: Journal    
DOI: 10.13181/mji.v6i1.801     Document Type: Article

References (31)

1. WHO. Progress in Human Reproduction Research, Special Programme of Research, Development and Research Training in Human Reproduction. Geneva: WHO, 1994.
2. Homonnai TZ, Paz FG. Methods for evaluating contraceptive technique. In: Cunningham GR, Schill WB, Hafez ESE, editors. Regulation of male fertility. The Haque: Martinus Nijhoff 1980: 41-50.
3. Patanelli DJ, editor. Hormonal control of male fertility. Washington: US Department of Health, Education and Welfare, 1978.
4. Schearer SB, Alvarez-Sanchez F, Anselmo J, Brenner PF, Coutinho E, Latham-Faundes A, et al. Hormonal contraception for men. Int J Androl 1978: suppl 2: 680-712.
5. Nieschlag E, Behre HE, Weinbauer GH. Hormonal methods for the regulation of male fertility. In: Serio M, editor. Perspective in Andrology. Serono Symposia Publications volume 53. New York: Raven Press, 1989: 517-29.
6. Swerdloff RS, Palacios A. Male contraception: Clinical assessment of chronic administration of testosterone enanthate. Int J Androl 1978: Suppl 2: 731-47.
7. Waites GMH. Male fertility regulation: The challenges for the year 2000. Br Med J 1993; 49: 210-21
8. Pangkahila W. Reversible azoospermia induced by an androgen-progestin combination regimen in Indonesian men. Int J Androl 1991; 14: 248-56.
9. World Health Organization. Comparison of testosterone enanthate plus DMPA and 19-nortestosterone hexoxyphenyl propionate plus DMPA for male contraception. Fertil Steril 1993; 60 (6): 1062-8.
10. Knuth UA, Behre H, Belkein L, Bents H, Nieschlag E. 19-Nortestosterone for male fertility regulation. In: Zatuchni GI, Goldsmith A, Spieler JM, Sciarra JJ, editors. Male contraception, advances and future prospects. Philadelphia. Harper and Row, 1986: 320-8.
11. Knuth UA, Yeung CH, Nieschlag E. Combination of 19-nortestosterone hexyloxyphenylpropionate (Anadur) and depot-medroxyprogesterone acetate (Clinovir) for male contraception. Fertil Steril 1989; 51: 1011-8.
12. Brenner PF, Mishell DR, Bernstein GS, Ortiz A. Study of medroxyprogesterone acetate and testosterone enanthate as a male contraceptive. Contraception 1977; 15: 679-91.
13. Alvarez-Sanchez F, Faundes A, Brache V, Leon P. Attainment and maintenance of azoospermia with combined monthly injection of depot medroxy progesterone acetate and testosterone enanthate. Contraception 1977; 15: 635-48.
14. Paulsen CA, Bremner WJ, Leonard JM. Male contraception clinical trials. In: Mishell DR Jr, editor. Advances in fertility research. New York: Raven Press, 1982: 157-70.
15. Alvarez-Sanchez F, Brache V, Leon P, Faundes A. Inhibition of spermatogenesis with monthly injection of depot medroxy progesterone acetate and low dose testosterone enanthate. Int J Androl 1979; 2: 136-49.
16. Faundes A, Brache V, Leon P, Schmidt F, Alvarez-Sanchez E. Sperm suppresion with monthly injections of medroxyprogesterone acetate combined with testosterone enanthate at a high dose (500 mg). Int J Androl 1981; 4: 235-45.
17. Melo JF, Coutinho EM. Inhibition of spermatogenesis in men with monthly injection of medroxy-progesterone acetate and testosterone enanthate. Contraception 1977; 15: 627-34.
18. Frick J, Bartsch G, Weiske WH. The effect of monthly depot medroxyprogesterone acetate and testosterone on human spermatogenesis. I. Uniform dosage level. Contraception 1977; 15: 649-68.
19. Frick J, Bartsch G, Weiske WH. The effect of monthly depot medroxyprogesterone acetate and testosterone on human spermatogenesis. I. High initial dose. Contraception 1977; 15: 669-77.
20. Hedman M, Gortleib C, Svanborg K, Bygdeman M, de la Torre B. Endocrine, seminal and peripheral effects of depot medroxyprogesterone acetate and testosterone enanthate in Men. IntJ Androl 1988; 11: 265-76.
21. World Health Organization. Contraceptive Efficacy of testosterone induced azoospermia in normal men. Lancet 1990; 336: 955-9.
22. Wallace EM, Wu FC. Effects of medroxy-progesterone acetate and testosterone enanthate on serum lipoprotein in Men. Contraception 1990; 41: 63-71.
23. Oppenheim DS, Greenspan SL, Zervas NT, Schoenfeld DA, Klibanski A. Elevated serum lipids in hypogonadal men with and without hyperprolactinemia. Annals of Internal Medicine. 1989; 111: 288-92.
24. Kasperk CH, Wergedal JE, Farley JR, Linkhart TA, Turner RT, Baylink DJ. Androgen directly stimulate proliferation of bone cells in vitro. Endocrinology 1989; 124: 1576-8.
25. Schulte-Beerbuhl M, Neischlag E. Comparison of testosterone, dihydrotestosterone, luteinizing hormone, and follicle-stimulating hormone in serum after injection of testosterone enanthate or testosterone cypionate. Fertil Steril 1980; 33: 201-3.
26. Sokol RZ, Palacios A, Campfield LA, Saul C, Swerdloff RS. Comparison of the kinetic of injectable testosterone in eugonadal and hypogonadal men. Fertil Steril 1982; 37: 425-30.
27. Schumeyer T, Neischlag E. Comparative pharmacokinetics of testosterone enanthate and testosterone cyclohexanecar-boxylate as assessed by serum salivary testosterone levels in normal men. IntJ Androl 1984; 7: 181-7.
28. Michael RP, Bonsall RW, Zumpe D. The behavioural thresholds of testosterone in castrated male rhesus monkeys (Maccaca mulatta). Horm Behav 1984; 18: 161-76.
29. Weinbauer GF, Jaekwert B, Yoon YD, Behre HM, Yeung CH, Nieschlag E. Pharmacokinetics and pharmacodynamics of testosterone enathate and dihydrotestosterone enanthate in non-human primates. Acta Endocrinol (Copenhagen) 1990; 122: 432-42.
30. Snyder PJ, Lawrence DA. Treatment of male hypogonadism with testosterone enanthate, J Clin Endocrinol Metab 1980; 51: 1335-9.
31. Wu FCW, Aitken RJ. Supression of sperm function by depot medroxyprogesterone acetate and testosterone enanthate in steroid male contraception. Fertil Steril 1989; 51: 691-8.