Alkylation of pyrazolones via the mitsunobu reaction

Heterocycles

Volumn 45, Issue 2, 1997, Pages 309-314

  Holzer, Wolfgang ^a   Plagens, Brigitte ^a   Lorenz, Karin ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0013483514     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-96-7657     Document Type: Article

References (13)

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2. J. Elguero, C. Marzin, A. R. Katritzky, and P. Linda, 'Advances in Heterocyclic Chemistry: The Tautomerism of Heterocycles', Suppl. 1, Academic Press, New York, 1976, pp. 313 - 336 and references cited therein.
3. K. Schofield, M. R. Grimmett, and B. T. R. Keene, 'Heteroaromatic Nitrogen Compounds: The Azoles', Cambridge University Press, Cambridge, 1976, pp. 85-91 and references cited therein.
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7. Thus, for instance, reaction of 4a with excessive epichlorohydrin under basic conditions selectively affords the corresponding N-alkyl compound, whereas application of 2,3-epoxypropanol under 'Mitsunobu' conditions leads to the O-alkyl isomer as the sole product
8. M. Lakkis, Z. Lakkis, G. J. Goetz-Grandmont, and J.-P. Brunette, Monatsh. Chem., 1991, 122, 9.
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11. T. Mills III and J. C. Roberson, 'Instrumental Data for Drug Analysis', 2nd Edition, Vol. 1, Elsevier, New York, 1987, pp. 130 - 131.
12. W. Freyer, H. Koeppel, R. Radeglia, and G. Malewski, J. Prakt. Chem. 1983, 325, 238.
13. W. Holzer and B. Plagens, Sci. Pharm., 1996, 64, 455 and references cited therein.