Mutagenic and toxic potentials of toxins produced by gambierdiscus toxicus and prorocentrum concavum

Journal of Aquatic Food Product Technology

Volumn 6, Issue 4, 1997, Pages 27-41

  Park, Douglas L ^a,b   Juranovic, Lillian R ^a,c   Rua, Sam M ^a   Nielsen, Chris A ^a   Ayala, Carlos E ^b  

^a UNIVERSITY OF ARIZONA   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c Frito Lay   (United States)

Author keywords

Ciguatera; Dinoflagellates; Gambierdiscus; Mutagenicity; Okadaic acid; Prorocentntm; Toxic extracts; Toxicity

Indexed keywords

EID: 0013220960     PISSN: 10498850     EISSN: 15470636     Source Type: Journal    
DOI: 10.1300/J030v06n04_03     Document Type: Article

References (21)

1. AOAC. 1990. Official Methods of Analysis, Association of Official Analytical Chemists International, Arlington, VA 22201-3301.
2. Besada, E.G., Loeblich, L.A., and Loeblich, A.R. III. 1982. Observations on tropical benthic dinoflagellates from ciguatera endemic areas Coolia monotis, Gambierdiscus toxicus, and Ostreopsis ovata. Bull. Mar. Sci. 32(3):723-735.
3. Doorenbos, N.J. 1984. Ciguatera toxins: where do we go from here? In: Seafood Toxins, E.R Ragelis, ed. Am. Chem. Soc., Washington, DC, pp, 60-73.
4. Doorenbos, N.J., Grandad, H.R., and Thomas, N. 1979. Ciguatera workshop, NJ. Sorrenbos (Chairperson). In; Toxic Dinoflagellate Bloom, Taylor, D.L. and Seliger, H.H., eds. Elsevier, NY, pp. 468-470.
5. Gamboa, P.M. and Park, D.L. 1985. Fractionation of extracts of Prorocentrum lima, Gambierdiscus toxicus, and ciguatoxic fish using counter current chromatography (Presented at 2nd Conference on Ciguatera, April 23-25, 1985, San Juan, Puerto Rico).
6. Gamboa, P.M., Park, D.L., and Fremy, J-M. 1990. Extraction and purification of toxic fractions from barracuda (Sphyraena barracuda) implicated in ciguatera poisoning. Proceeding of the 3rd International Conference on Ciguatera Fish Poisoning, April 30-May 4, 1990, Lajas, Puerto Rico.
7. Granade, H.R., Cheng, P.C., and Doorenbos, N.J., 1976. Ciguatera I: Brine Shrimp (Artemia salina L.) larval assay for ciguatera toxins. J. Pharm. Sci. 65:1414-1415.
8. Hoffman, P.A., Granade, H.R., and McMillan, J.P. 1983. The mouse ciguatoxin bioassay: A dose response curve and symptomatology analysis. Toxicon. 21(3):363-369.
9. Juranovic, L.R. and Park, D.L., 1991. Foodbome toxins of marine origin: Ciguatera. Rev. Environ. Contam. and Toxicol., Vol. 117, pp. 51-94.
10. Juranovic, L.R., Park, D.L., Fremy, J-M., Nielsen, C.A., Ali, S.S., and Ayala, C.E. 1997. Isolation and separation of toxins produced by Gambierdiscus toxicus and Prorocentrum concavum. J. Aquat. Food Prod. Techn. 6(4): 5-25.
11. Maron, D.M. and Ames, B.N. 1983. Revised methods for the Salmonella mutagenicity test. Mutat. Research 113:173-215.
12. Miller, D.M., Dickey, R.W., and Tindall, D.R. 1984. Lipid extracted toxins from a dinoflagellate, Gambierdiscus toxicus. In: Seafood Tbxins, E.P. Ragelis, ed. ACS Symposium Series 262, pp. 241-255.
13. Murakami, Y., Oshima, Y., and Yasumoto, T. 1982. Identification of okadaic acid as a toxic component of a marine dinoflagellate, Pmrocentrum lima. Bull. Jpn. Soc. Sci. Fish. 48:69-72.
14. National Academy of Sciences 1991. Report on Seafood Safety. Institute of Medicine, National Academy of Sciences, Washington, DC.
15. Park, D.L., Aguirre-Flores, I., Scott, W.F., and Alterman, E. 1986. Evaluation of chicken embryo, brine shrimp, and bacterial bioassays for saxitoxin. J. Toxicol. Environ. Health 18:589-594.
16. Park, D.L. and Goldsmith, C.H. 1991. Inter-laboratory validation of the solid- phase immunobead assay for the detection of toxins associated with ciguatera poisoning. Presented at the 5th International Conference on Toxic Marine Phytoplankton, October 28-November 1, 1991, Newport, Rhode Island.
17. Ragelis, E.P. 1984. Ciguatera seafood poisoning-Overview. In: Seafood Toxins, E.P. Ragelis, ed. American Chemical Society, Washington, DC, pp. 22-36.
18. Sawyer, P., Jallow, D., Scheuer, P., York, R., McMillian, J., Withers, N., Fuden- berg, H., and Higerd, T. 1984. Effect of ciguatera-associated toxins on body temperature in mice. In: Seafood Toxins, E. Ragelis, ed. American Chemical Society, Washington, DC, pp. 321-329.
19. Tindall, D.R., Dickey, R.W., Carlson, R.D., and Morey-Gaines, G. 1984. Cigua- toxic dinoflageltates from the Caribbean Sea. In: Seafood Toxins, E.P. Ragelis, ed. Am. Chem. Soc., Washington, DC, pp. 225-240.
20. World Health Organization. 1984. Aquatic (marine and fresh water) biotoxins. Environmental Health Criteria 37, Geneva, Switzerland.
21. Yasumoto, T., Nakajima, I., Oshima, Y, and Bagnis, R. 1979. A new toxic dinoflagellate found in association with ciguatera. In: Toxic Dinoflagellate Blooms, Taylor, D.L. and Seliger, H., eds. Elsevier, Netherlands, pp. 65-72.