Modular synthesis of amine-functionalized oxazolines

Organic Letters

Volumn 4, Issue 20, 2002, Pages 3399-3401

  Rajaram, Sridhar ^a   Sigman, Matthew S ^a  

^a UNIVERSITY OF UTAH   (United States)

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ARTICLE;

EID: 0013159872     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0264758     Document Type: Article

References (42)

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27. Low concentrations were necessary to control Fmoc decomposition during the reaction.
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39. Phenylglycine is often a test substrate for racemization in peptide couplings; see: Bodanszky, M. Principles of Peptide Synthesis, 2nd ed.; Springer-Verlag: Berlin, 1993.
40. Using diethylamine to deprotect oxazoline 6 was unreliable.
41. For recent examples of the use of oxazoline amine cores in asymmetric catalysis, see: (a) Pastor, I. M.; Adolfsson, H. Tetrahedron Lett. 2002, 43, 1743.
42. (b) Wipf, P.; Wang, X. Org. Lett. 2002, 4, 1197.