Implementation of intensity-modulated laser diodes in time-resolved, pump-probe fluorescence microscopy

Applied Optics

Volumn 40, Issue 7, 2001, Pages 1109-1115

  Dong, Chen Yuan ^a,b   Buehler, Christof ^c   So, Peter T C ^a   French, Todd ^d   Gratton, Enrico ^e  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c PAUL SCHERRER INSTITUTE   (Switzerland)

^d LJL BioSystems   (United States)

^e University of Illinois at Urbana Champaign   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE; LIGHT SOURCES; OPTICAL PUMPING; STIMULATED EMISSION;

PUMP-PROBE FLUORESCENCE MICROSCOPY;

SEMICONDUCTOR LASERS;

EID: 0012972270     PISSN: 1559128X     EISSN: 21553165     Source Type: Journal    
DOI: 10.1364/AO.40.001109     Document Type: Article

References (20)

1. D. K. Evans, ed., Laser Applications in Physical Chemistry (Marcel Dekker, New York, 1989).
2. G. R. Fleming, Chemical Applications of Ultrafast Spectroscopy (Oxford U. Press, New York, 1986).
3. F. E. Lytle, R. M. Parish, and W. T. Barnes, “An introduction to time-resolved pump-probe spectroscopy,” Appl. Spectrosc. 39, 444-451 (1985).
4. J. Zhou, G. Taft, C. P. Huang, I. P. Christov, H. C. Kapteyn, and N. M. Murnane, “Sub-10 fs pulse generation in Ti:sap-phire: capabilities and ultimate limits,” in Ultrafast Phenomena IX, P. F. Barbara, W. H. Knox, G. A. Mourou, and A. H. Zewail, eds. (Springer-Verlag, Berlin, 1995), pp. 39-40.
5. L. Xu, C. Spielmann, F. Krausz, and R. Szipocs, “Ultrabroadband ring oscillator for sub-10-fs pulse generation,” Opt. Lett. 21, 1259-1261 (1996).
6. I. P. Christov, V. Stoev, M. M. Murnane, and H. C. Kapteyn, “Sub-10-fs operation of Kerr-lens mode-locked lasers,” Opt. Lett. 21, 1493-1495 (1996).
7. R. M. Hochstrasser and C. K. Johnson, “Biological processes studied by ultrafast laser techniques,” in Ultrashort Laser Pulses, W. Kaiser, ed. (Springer-Verlag, New York, 1988), pp. 357-417.
8. P. A. Elzinga, R. J. Kneisler, F. E. Lytle, G. B. King, and N. M. Laurendeau, “Pump-probe method for fast analysis of visible spectral signatures utilizing asynchronous optical sampling,” Appl. Opt. 26, 4303-4309 (1987).
9. P. A. Elzinga, F. E. Lytle, Y. Jian, G. B. King, and N. M. Laurendeau, “Pump-probe spectroscopy by asynchronous optical sampling,” Appl. Spectrosc. 41, 2-4 (1987).
10. J. R. Lakowicz, I. Gryczynski, V. Bogdanov, and J. Kusba, “Light quenching and fluorescence depolarization of Rhodamine-B and applications of this phenomenon to biophysics,” J. Phys. Chem. 98, 334-342 (1994).
11. J. Kusba, V. Bogdanov, I. Gryczynski, and J. R. Lakowicz, “Theory of light quenching: effects on fluorescence polarization, intensity, and anisotropy decays,” Biophys. J. 67, 2024-2040 (1994).
12. C. Y. Dong, P. T. C. So, T. French, and E. Gratton, “Fluorescence lifetime imaging by asynchronous pump-probe microscopy,” Biophys. J. 69, 2234-2242 (1995).
13. C. Y. Dong, P. T. C. So, C. Buehler, and E. Gratton, “Spatial resolution in scanning pump-probe fluorescence microscopy,” Optik 106, 7-14 (1997).
14. C. Buehler, C. Y. Dong, P. T. C. So, and E. Gratton, “Time-resolved polarization imaging by pump-probe (stimulated emission) fluorescence microscopy,” Biophys. J. 79, 536-549 (2000).
15. M. Born and E. Wolf, Principles of Optics, 5th ed. (Pergamon, Oxford, UK, 1985).
16. C. J. R. Sheppard and M. Gu, “Image formation in two-photon fluorescence microscopy,” Optik 86, 104-106 (1990).
17. M. Gu and C. J. R. Sheppard, “Effects of a finite-sized pinhole on 3D image formation in confocal two-photon fluorescence microscopy,” J. Mod. Opt. 40, 2009-2024 (1993).
18. I. J. Cox, C. J. R. Sheppard, and T. Wilson, “Superresolution by confocal fluorescent microscopy,” Optik 60, 391-396 (1982).
19. J. R. Lakowicz, Principles of Fluorescence Spectroscopy (Plenum, New York, 1983).
20. R. P. Haugland, Handbook of Fluorescent Probes and Research Chemicals, 5th ed., K. D. Larison, ed. (Molecular Probes, Eugene, Ore., 1989).