메뉴 건너뛰기




Volumn 29, Issue 3, 1998, Pages 517-523

Effects of Histamine H1 Receptor Antagonists Promethazine and Homochlorcyclizine on Steady-State Plasma Concentrations of Haloperidol and Reduced Haloperidol

Author keywords

cyto chrome P450 2D6; haloperidol; homochlorcyclizine; promethazine; reduced haloperidol

Indexed keywords


EID: 0012673758     PISSN: 03881601     EISSN: 18828272     Source Type: Journal    
DOI: 10.3999/jscpt.29.517     Document Type: Article
Times cited : (1)

References (19)
  • 1
    • 0026538627 scopus 로고
    • Haloperidol plasma levels and clinical response: a therapeutic window relationship
    • Van Putten, T., Marder, S. R., Mintz, J., et al.: Haloperidol plasma levels and clinical response: a therapeutic window relationship. Am. J. Psychiatry, 149: 500-505 (1992).
    • (1992) Am. J. Psychiatry , vol.149 , pp. 500-505
    • Van Putten, T.1    Marder, S.R.2    Mintz, J.3
  • 2
    • 0030993544 scopus 로고    scopus 로고
    • Blood levels of reduced haloperidol versus clinical efficacy and extrapyramidal side effects of haloperidol
    • Lane, H. Y., Lin, H. N., Hu, O. Y. P., et al.: Blood levels of reduced haloperidol versus clinical efficacy and extrapyramidal side effects of haloperidol. Prog. Neuropsychopharmacol. Biol. Psychiatry, 21: 299-311 (1997).
    • (1997) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.21 , pp. 299-311
    • Lane, H.Y.1    Lin, H.N.2    Hu, O.Y.P.3
  • 3
    • 0028358360 scopus 로고
    • Metabolism of haloperidol: clinical implications and unanswered questions
    • Tsang, M. W., Shader, R. I. and Greenblatt, D. J.: Metabolism of haloperidol: clinical implications and unanswered questions. J. Clin. Psychopharmacol., 14: 159-162 (1994).
    • (1994) J. Clin. Psychopharmacol. , vol.14 , pp. 159-162
    • Tsang, M.W.1    Shader, R.I.2    Greenblatt, D.J.3
  • 4
    • 0030930935 scopus 로고    scopus 로고
    • Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol
    • Fang, J., Baker, G. B., Silverstone, P. H., et al.: Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol. Cell. Mol. Neurobiol., 17: 227-233 (1997).
    • (1997) Cell. Mol. Neurobiol. , vol.17 , pp. 227-233
    • Fang, J.1    Baker, G.B.2    Silverstone, P.H.3
  • 5
    • 0025782876 scopus 로고
    • Oxidation of reduced haloperidol to haloperidol: involvement of human P450I1D6 (sparteine/debrisoquine monooxygenase)
    • Tyndale, R. F., Kalow, W. and Inaba, T.: Oxidation of reduced haloperidol to haloperidol: involvement of human P450I1D6 (sparteine/debrisoquine monooxygenase). Br. J. Clin. Pharmacol., 31: 655-660 (1991).
    • (1991) Br. J. Clin. Pharmacol. , vol.31 , pp. 655-660
    • Tyndale, R.F.1    Kalow, W.2    Inaba, T.3
  • 6
    • 0026692983 scopus 로고
    • Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype
    • LLerena, A., Alm, C., Dahl, M. L., et al.: Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype. Ther. Drug Monit., 14: 92-97 (1992).
    • (1992) Ther. Drug Monit. , vol.14 , pp. 92-97
    • LLerena, A.1    Alm, C.2    Dahl, M.L.3
  • 7
    • 0026780430 scopus 로고
    • Haloperidol disposition is dependent on the debrisoquine hydroxylation phenotype: increased plasma levels of the reduced metabolite in poor metabolizers
    • LLerena, A., Dahl, M. L., Ekqvist, B., et al.: Haloperidol disposition is dependent on the debrisoquine hydroxylation phenotype: increased plasma levels of the reduced metabolite in poor metabolizers. Ther. Drug Monit., 14: 261-264 (1992).
    • (1992) Ther. Drug Monit. , vol.14 , pp. 261-264
    • LLerena, A.1    Dahl, M.L.2    Ekqvist, B.3
  • 8
    • 0003092787 scopus 로고    scopus 로고
    • Histamine, bradykinin, and their antagonists
    • Goodman, L. S. and Gilman, A.(Ed.) 9th ed. Mac Millan, N. Y.
    • Babe, Jr, K. S. and Serafin, W. E.: Histamine, bradykinin, and their antagonists. Goodman, L. S. and Gilman, A.(Ed.): The pharmacological basis of therapeutics, 9th ed. Mac Millan, N. Y., pp.581-600 (1996).
    • (1996) The pharmacological basis of therapeutics , pp. 581-600
    • Babe, K.S.1    Serafin, W.E.2
  • 9
    • 0029798503 scopus 로고    scopus 로고
    • CYP2D6 is the principal cytochrome P450 responsible for metabolism of the histamine H1 antagonist promethazine in human liver microsomes
    • Nakamura, K., Yokoi, T., Inoue, K., et al.: CYP2D6 is the principal cytochrome P450 responsible for metabolism of the histamine H1 antagonist promethazine in human liver microsomes. Pharmacogenetics, 6: 449-457 (1996).
    • (1996) Pharmacogenetics , vol.6 , pp. 449-457
    • Nakamura, K.1    Yokoi, T.2    Inoue, K.3
  • 10
    • 0020676140 scopus 로고
    • Pharmacokinetics of promethazine and its sulphoxide metabolite after intravenous and oral administration to man
    • Taylor, G., Houston, J. B., Shaffer, J., et al.: Pharmacokinetics of promethazine and its sulphoxide metabolite after intravenous and oral administration to man. Br. J. Clin. Pharmacol., 15: 287-293 (1983).
    • (1983) Br. J. Clin. Pharmacol. , vol.15 , pp. 287-293
    • Taylor, G.1    Houston, J.B.2    Shaffer, J.3
  • 11
    • 0022899555 scopus 로고
    • The molecular mechanism of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation
    • Meyer, U. A., Gut, J., Kronbach, T., et al.: The molecular mechanism of two common polymorphisms of drug oxidation-evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation. Xenobiotica, 16: 449-464 (1986).
    • (1986) Xenobiotica , vol.16 , pp. 449-464
    • Meyer, U.A.1    Gut, J.2    Kronbach, T.3
  • 12
    • 0003408003 scopus 로고
    • American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders
    • 4th ed. American Psychiatric Association, Washington D. C.
    • American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. American Psychiatric Association, Washington D. C.(1994).
    • (1994)
  • 13
    • 0025253074 scopus 로고
    • Reversible metabolism of haloperidol and reduced haloperidol in Chinese schizophrenic patients
    • Jann, M. W., Lam, Y. W. F. and Chang, W. H.: Reversible metabolism of haloperidol and reduced haloperidol in Chinese schizophrenic patients. Psychopharmacology, 101: 107-111 (1990).
    • (1990) Psychopharmacology , vol.101 , pp. 107-111
    • Jann, M.W.1    Lam, Y.W.F.2    Chang, W.H.3
  • 14
    • 0018897689 scopus 로고
    • Effect of anticonvulsants on plasma haloperidol and thioridazine levels
    • Linnoila, M., Viukari, M., Vaisanen, K., et al.: Effect of anticonvulsants on plasma haloperidol and thioridazine levels. Am. J. Psychiatry, 137: 819-821 (1980).
    • (1980) Am. J. Psychiatry , vol.137 , pp. 819-821
    • Linnoila, M.1    Viukari, M.2    Vaisanen, K.3
  • 15
    • 0022589659 scopus 로고
    • Minicompendium of rating scales for states of anxiety, depression, mania, schizophrenia with corresponding DSM-III syndromes
    • Beck, P., Kastrup, M. and Rafaelsen, O. J.: Minicompendium of rating scales for states of anxiety, depression, mania, schizophrenia with corresponding DSM-III syndromes. Acta Psychiatr. Scand., 73 (Suppl. 326): 1-37 (1986).
    • (1986) Acta Psychiatr. Scand. , vol.73 , pp. 1-37
    • Beck, P.1    Kastrup, M.2    Rafaelsen, O.J.3
  • 16
    • 0023244845 scopus 로고
    • The UKU side effect rating scale: a new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients
    • Lingjarde, O., Ahlfors, U. G., Bech, P., et al.: The UKU side effect rating scale: a new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr. Scand., 76 (Suppl. 334): 1-100 (1987).
    • (1987) Acta Psychiatr. Scand. , vol.76 , pp. 1-100
    • Lingjarde, O.1    Ahlfors, U.G.2    Bech, P.3
  • 17
    • 0024430422 scopus 로고
    • Determination of bromperidol in serum by automated column-switching high performance liquid chromatography
    • Hikida, K., Inoue, Y., Miyazaki, T., et al.: Determination of bromperidol in serum by automated column-switching high performance liquid chromatography. J. Chromatogr., 495: 227-234 (1989).
    • (1989) J. Chromatogr. , vol.495 , pp. 227-234
    • Hikida, K.1    Inoue, Y.2    Miyazaki, T.3
  • 18
    • 9844262794 scopus 로고    scopus 로고
    • Relationship between the CYP2D6 genotype and the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazlne
    • Mihara, K., Otani, K., Suzuki, A., et al.: Relationship between the CYP2D6 genotype and the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazlne. Psychopharmacology, 133: 95-98 (1997).
    • (1997) Psychopharmacology , vol.133 , pp. 95-98
    • Mihara, K.1    Otani, K.2    Suzuki, A.3
  • 19
    • 0029028932 scopus 로고
    • Geographical/interracial differences in polymorphic drug oxidation
    • Current state of knowledge of cytochrome P450 (CYP) 2D6 and 2C19
    • Bertilsson, L.: Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochrome P450 (CYP) 2D6 and 2C19. Clin. Pharmacokinet., 29: 192-209 (1995).
    • (1995) Clin. Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.