Pharmacological effects of extracts from Valeriana adscendens Trel. II. Effects on GABA uptake and amino acids

Phytotherapy Research

Volumn 17, Issue 6, 2003, Pages 661-664

  De Feo, Vincenzo ^a   Faro, Carlos ^b  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Amino acids neurotransmitters; GABA; Synaptosomes; Valeriana adscendens

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID; AMINO ACID RECEPTOR AFFECTING AGENT; METHANOL; NEUROLEPTIC AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG; VALERIANA ADSCENDENS EXTRACT;

4 AMINOBUTYRIC ACID UPTAKE; AMINO ACID ANALYSIS; AMINO ACID COMPOSITION; AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; DRUG EFFECT; DRUG ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEDICINAL PLANT; NONHUMAN; RAT; SYNAPTOSOME; VALERIANA ADSCENDENS;

ANIMALS; ANTIPSYCHOTIC AGENTS; GAMMA-AMINOBUTYRIC ACID; MALE; NEUROTRANSMITTER AGENTS; PHYTOTHERAPY; PLANT COMPONENTS, AERIAL; PLANT EXTRACTS; RATS; RATS, WISTAR; SYNAPTOSOMES; VALERIAN;

VALERIANA; VALERIANACEAE;

EID: 0012209960     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1225     Document Type: Article

References (18)

1. Allport NL. 1943. The Chemistry and Pharmacy of Vegetable Drugs. George Newnes: London; 159-161.
2. Bruneton J. 1993. Pharmacognosie: Phytochimie Plantes Médicinales. TDC & DOC Lavoisier: Londres; 481-485.
3. Capasso A, De Feo V, De Simone F, Sorrentino L. 1996. Pharmacological Effects of Aqueous Extract from Valeriana adscendens. Phytotherapy Res 10: 309-312.
4. Cavadas C, Araujo I, Cotrim MD et al. 1995. In vitro study on the interaction of Valeriana officinalis L. extracts and their amino acids on the GABA receptor in rat brain. Arzneimittelforschung 45: 753-755.
5. De Feo V. 1992. Medicinal and Magical Plants in the northern Peruvian Andes. Fitoterapia LXIII: 417-440.
6. Dunaev VV, Trzhetsinskii SD, Tishkin VS et al. 1987. Biological activity of the sum of valepotriates isolated from Valeriana alliariifolia. Farmakol Toksikol 50: 33-37.
7. Hajos F. 1975. An improved method for the preparation of synaptosomal fractions in high purity. Brain Res 95: 485-489.
8. Houghton PJ. 1999. The scientific basis for the reputed activity of Valerian. J Pharm Pharmacol 51: 505-512.
9. Leathwood PD, Chauffard F. 1985. Aqueous extract of valerian reduces latency to fall asleep in man. Planta Med 51: 144-147.
10. Leathwood PD, Chauffard F, Heck E, Munoz-Box R. 1982. Aqueous ectract of valerian (Valeriana officinalis) improves sleep qualitiy in man. Pharmacol Biochem Behav 17: 65-72.
11. Leuschner J, Müller J, Rudmann M. 1993. Characterization of central nervous depressant activity of commercially available valerian root extract. Arzneimittelforschung 43: 638-641.
12. Marfori P. 1941. Trattato di Farmacologia e Terapia. Casa Editrice Libraria V. Idelson: Napoli.
13. 3H]GABA release. Neurochem Res 24: 1373-1378.
14. Santos MS, Ferreira F, Cunha AP et al. 1994a. An Aqueous Extract of Valerian Influences the transport of GABA in Synaptosomes. Planta Med 60: 278-279.
15. 3H]GABA Release in Synaptosomes. Planta Med 60: 475-476.
16. Santos MS, Ferreira F, Cunha AP et al. 1994c. Synaptosomal GABA release as Influenced by Valerian Root Extract. Involvement of the GABA carrier. Arch Int Pharmacodyn Thér 327: 220-231.
17. Soukup J. 1987. Vocabulario de los nombres tradicionales de la Flora Peruana y catalogo de los generos. Editorial Salesiana: Lima; 420.
18. Taddei I, Giachetti D. 1980. Fondamenti di Farmacognosia. Editoriale Grasso: Milano.