메뉴 건너뛰기




Volumn 38, Issue 1, 1998, Pages 25-38

Midkine, a new heparin-binding growth/differentiation factor: Expression and distribution during embryogenesis and pathological status

Author keywords

Differentiation; Embryogenesis; Growth factor; Midkine (MK); Pathogenesis; Proliferation; Teratocarcinoma

Indexed keywords


EID: 0012094729     PISSN: 09143505     EISSN: 17414520     Source Type: Journal    
DOI: 10.1111/j.1741-4520.1998.tb00327.x     Document Type: Review
Times cited : (2)

References (63)
  • 1
    • 0026316096 scopus 로고
    • Growth factors and cancer
    • Aaronson, S.A. (1991) Growth factors and cancer. Science, 254:1146-1153.
    • (1991) Science , vol.254 , pp. 1146-1153
    • Aaronson, S.A.1
  • 3
    • 0024339705 scopus 로고
    • The heparin-binding (fibroblast) growth factor family of proteins
    • Burgess, W.H. and Maciag, T. (1989) The heparin-binding (fibroblast) growth factor family of proteins. Annu. Rev. Biochem., 58: 575-606.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 575-606
    • Burgess, W.H.1    Maciag, T.2
  • 4
    • 0030904197 scopus 로고    scopus 로고
    • An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis
    • Choudhuri, R., Zhang, H.-H., Donnini, S., Ziche, M. and Bicknell, R. (1997) An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis. Cancer Res., 57: 1814-1819.
    • (1997) Cancer Res. , vol.57 , pp. 1814-1819
    • Choudhuri, R.1    Zhang, H.-H.2    Donnini, S.3    Ziche, M.4    Bicknell, R.5
  • 5
    • 0026025755 scopus 로고
    • Growth factors in development, transformation, and tmorigenesis
    • Cross, M. and Derten, T.M. (1991) Growth factors in development, transformation, and tmorigenesis. Cell, 64: 271-280.
    • (1991) Cell , vol.64 , pp. 271-280
    • Cross, M.1    Derten, T.M.2
  • 7
    • 0027688352 scopus 로고
    • Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues
    • Garver, R.I., Chan, C.S. and Milner, P.G. (1993) Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues. Am. J. Respir. Cell Mol. Biol., 9: 463-466.
    • (1993) Am. J. Respir. Cell Mol. Biol. , vol.9 , pp. 463-466
    • Garver, R.I.1    Chan, C.S.2    Milner, P.G.3
  • 8
    • 0028021573 scopus 로고
    • Midkine and pleiotrophin expression in normal and malignant breast tissue
    • Garver, R.I., Radford, D.M., Donis-Keller, H., Wick, M.R. and Milner, P.G. (1994) Midkine and pleiotrophin expression in normal and malignant breast tissue. Cancer, 74: 1584-1590.
    • (1994) Cancer , vol.74 , pp. 1584-1590
    • Garver, R.I.1    Radford, D.M.2    Donis-Keller, H.3    Wick, M.R.4    Milner, P.G.5
  • 9
    • 0023520940 scopus 로고
    • Identification of a receptor for the morphoge retinoic acid
    • Giguere, V., Ong, E.S., Segui, P. and Evans, R.M. (1988) Identification of a receptor for the morphoge retinoic acid. Nature, 330: 624-629.
    • (1988) Nature , vol.330 , pp. 624-629
    • Giguere, V.1    Ong, E.S.2    Segui, P.3    Evans, R.M.4
  • 10
    • 0030794570 scopus 로고    scopus 로고
    • Midkine and secondary neurulation
    • Griffith, M. (1997) Midkine and secondary neurulation. Teratology. 55: 213-223.
    • (1997) Teratology , vol.55 , pp. 213-223
    • Griffith, M.1
  • 11
    • 0024447087 scopus 로고
    • Growth factors as trasforming proteins
    • Heldin, C.H. and Westermark, B. (1989) Growth factors as trasforming proteins. Eur. J. Biochem., 184: 487-496.
    • (1989) Eur. J. Biochem. , vol.184 , pp. 487-496
    • Heldin, C.H.1    Westermark, B.2
  • 12
    • 0023319583 scopus 로고
    • Retinoic acidinduced differentiation of the human promyelocytic leukemia cell line, HL-60, and fresh human leukemia cell in primary culture: A model for differentiation inducing therapy of leukemia
    • Imaizumi, M. and Breitman, T.R. (1987) Retinoic acidinduced differentiation of the human promyelocytic leukemia cell line, HL-60, and fresh human leukemia cell in primary culture: a model for differentiation inducing therapy of leukemia. Eur. J. Haematol., 38: 289-302.
    • (1987) Eur. J. Haematol. , vol.38 , pp. 289-302
    • Imaizumi, M.1    Breitman, T.R.2
  • 14
    • 0026570216 scopus 로고
    • Diffusible factors in vertebrate embryonic induction
    • Jessell, T.M. and Melton, D.A. (1992) Diffusible factors in vertebrate embryonic induction. Cell, 68: 257-270.
    • (1992) Cell , vol.68 , pp. 257-270
    • Jessell, T.M.1    Melton, D.A.2
  • 15
    • 0025304674 scopus 로고
    • A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis
    • Kadomatsu, K., Huang, R.-P., Suganuma, T., Murata, F. and Muramatsu, T. (1990) A retinoic acid responsive gene MK found in the teratocarcinoma system is expressed in spatially and temporally controlled manner during mouse embryogenesis. J. Cell Biol., 110: 607-616.
    • (1990) J. Cell Biol. , vol.110 , pp. 607-616
    • Kadomatsu, K.1    Huang, R.-P.2    Suganuma, T.3    Murata, F.4    Muramatsu, T.5
  • 16
    • 0023934902 scopus 로고
    • CDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis
    • Kadomatsu, K., Tomomura, M. and Muramatsu, T. (1988) cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis. Biochem. Biophys. Res. Comm., 151: 1312-1318.
    • (1988) Biochem. Biophys. Res. Comm. , vol.151 , pp. 1312-1318
    • Kadomatsu, K.1    Tomomura, M.2    Muramatsu, T.3
  • 17
    • 0027176346 scopus 로고
    • Midkine gene (MDK), a gene for prenatal differentiation and neuroregulation, maps to band 11p11.2 by fluorescence in situ hybridization
    • Kaname, T., Kuwano, A., Murano, I., Uehara, K., Muramatsu, T. and Kajii, T. (1993) Midkine gene (MDK), a gene for prenatal differentiation and neuroregulation, maps to band 11p11.2 by fluorescence in situ hybridization. Genomics, 17: 514-515.
    • (1993) Genomics , vol.17 , pp. 514-515
    • Kaname, T.1    Kuwano, A.2    Murano, I.3    Uehara, K.4    Muramatsu, T.5    Kajii, T.6
  • 18
    • 0027364131 scopus 로고
    • Midkine, a novel neurotrophic factor, promotes survival of mesencephalic neurons in culture
    • Kikuchi, S., Muramatsu, H., Muramatsu, T. and Kim, S.U. (1993) Midkine, a novel neurotrophic factor, promotes survival of mesencephalic neurons in culture. Neurosci. Lett., 160: 9-12.
    • (1993) Neurosci. Lett. , Issue.160 , pp. 9-12
    • Kikuchi, S.1    Muramatsu, H.2    Muramatsu, T.3    Kim, S.U.4
  • 20
    • 0023868741 scopus 로고
    • Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization
    • Koury, S.T., Bondurant, M.C. and Koury, M.J. (1988) Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization. Blood, 71: 524-527.
    • (1988) Blood , vol.71 , pp. 524-527
    • Koury, S.T.1    Bondurant, M.C.2    Koury, M.J.3
  • 21
    • 0025130564 scopus 로고
    • Heparin-binding neurotrophic factor (HBNF) and MK, members of a new family of homologous, developmentally regulated proteins
    • Kovesdi, I., Fairhurst, J.L., Kretschmer, P.J. and Bhlen, P. (1990) Heparin-binding neurotrophic factor (HBNF) and MK, members of a new family of homologous, developmentally regulated proteins. Biochem. Biophys. Res. Comm., 172: 850-854.
    • (1990) Biochem. Biophys. Res. Comm. , vol.172 , pp. 850-854
    • Kovesdi, I.1    Fairhurst, J.L.2    Kretschmer, P.J.3    Bhlen, P.4
  • 22
    • 0025938399 scopus 로고
    • Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins
    • Kretschmer, P.J., Fairhurst, J.L., Decker, M.M., Chan, C.P., Gluzman, Y., Bhlen, P. and Kovesdi, I. (1991) Cloning, characterization and developmental regulation of two members of a novel human gene family of neurite outgrowth-promoting proteins. Growth Factors, 5: 99-114.
    • (1991) Growth Factors , vol.5 , pp. 99-114
    • Kretschmer, P.J.1    Fairhurst, J.L.2    Decker, M.M.3    Chan, C.P.4    Gluzman, Y.5    Bhlen, P.6    Kovesdi, I.7
  • 24
    • 0028279390 scopus 로고
    • Mapping and characterization of a retinoic acidresponsive enhancer of midkine, a novel heparin binding growth/differentiation factor with neurotrophic activity
    • Matsubara, S., Take, M., Pedraza, C. and Muramatsu, T. (1994) Mapping and characterization of a retinoic acidresponsive enhancer of midkine, a novel heparin binding growth/differentiation factor with neurotrophic activity. J. Biochem. (Tokyo), 115: 1088-1096.
    • (1994) J. Biochem. (Tokyo) , vol.115 , pp. 1088-1096
    • Matsubara, S.1    Take, M.2    Pedraza, C.3    Muramatsu, T.4
  • 25
    • 0025296412 scopus 로고
    • Structure of a retinoic acidresponsive gene, MK, which is transiently activated during the differentiation of embryonal carcinoma cells and the mid-gestation period of mouse embryogenesis
    • Matsubara, S., Tomomura, M., Kadomatsu, K. and Muramatsu, T. (1990) Structure of a retinoic acidresponsive gene, MK, which is transiently activated during the differentiation of embryonal carcinoma cells and the mid-gestation period of mouse embryogenesis. J. Biol. Chem., 265: 9441-9443.
    • (1990) J. Biol. Chem. , vol.265 , pp. 9441-9443
    • Matsubara, S.1    Tomomura, M.2    Kadomatsu, K.3    Muramatsu, T.4
  • 28
    • 0028233266 scopus 로고
    • A novel family of heparin-binding growth factors, pleiotrophin and midkine is expressed in the developing rat cerebral cortex
    • Matsumoto, K., Wanaka, A., Takatsuji, K., Muramatsu, H., Muramatsu, T. and Tohyama, M. (1994b) A novel family of heparin-binding growth factors, pleiotrophin and midkine is expressed in the developing rat cerebral cortex. Dev. Brain Res., 79: 229-241.
    • (1994) Dev. Brain Res. , vol.79 , pp. 229-241
    • Matsumoto, K.1    Wanaka, A.2    Takatsuji, K.3    Muramatsu, H.4    Muramatsu, T.5    Tohyama, M.6
  • 29
    • 0019947366 scopus 로고
    • Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line
    • McBurney, M.W., Jones-Villeneuve, E.M.V., Edwards, M.K.S. and Anderson, P.J. (1982) Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature, 299 165-167
    • (1982) Nature , vol.299 , pp. 165-167
    • McBurney, M.W.1    Jones-Villeneuve, E.M.V.2    Edwards, M.K.S.3    Anderson, P.J.4
  • 30
    • 0025188130 scopus 로고
    • The wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain
    • McMahon, A.P. and Bradley, A. (1990) The wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell, 62: 1073-1085.
    • (1990) Cell , vol.62 , pp. 1073-1085
    • McMahon, A.P.1    Bradley, A.2
  • 31
    • 0027216805 scopus 로고
    • Retinoic acid responsive gene product, midkine (MK), has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture
    • Michikawa, M.. Kikuchi, S., Muramatsu, H., Muramatsu, T. and Kim, S.U. (1993) Retinoic acid responsive gene product, midkine (MK), has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture. J. Neurosci. Res., 35: 530-539.
    • (1993) J. Neurosci. Res. , vol.35 , pp. 530-539
    • Michikawa, M.1    Kikuchi, S.2    Muramatsu, H.3    Muramatsu, T.4    Kim, S.U.5
  • 33
    • 0028851033 scopus 로고
    • Expression of the heparinbinding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelialmesenchymal interactions during fetal development and organogenesis
    • Mitsiadis, T.A., Salmivirta, M., Muramatsu, T., Muramatsu, H., Rauvala, H., Lehtonen, E., Jalkanen, M. and Thesleff, I. (1995) Expression of the heparinbinding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelialmesenchymal interactions during fetal development and organogenesis. Development, 121: 37-51.
    • (1995) Development , vol.121 , pp. 37-51
    • Mitsiadis, T.A.1    Salmivirta, M.2    Muramatsu, T.3    Muramatsu, H.4    Rauvala, H.5    Lehtonen, E.6    Jalkanen, M.7    Thesleff, I.8
  • 34
    • 0022391566 scopus 로고
    • Cell-surface changes during in vitro differentiation of pluripotent embryonal carcinoma cells
    • Muramatsu, H., Hamada, H., Noguchi, S., Kamada, K. and Muramatsu, T. (1985) Cell-surface changes during in vitro differentiation of pluripotent embryonal carcinoma cells. Dev. Biol., 110: 284-296.
    • (1985) Dev. Biol. , vol.110 , pp. 284-296
    • Muramatsu, H.1    Hamada, H.2    Noguchi, S.3    Kamada, K.4    Muramatsu, T.5
  • 36
    • 0025800487 scopus 로고
    • Purification of recombinant midkine and examination of its biological activities: Functional comparison of new heparin binding factors
    • Muramatsu, H. and Muramatsu, T. (1991) Purification of recombinant midkine and examination of its biological activities: functional comparison of new heparin binding factors. Biochem. Biophys. Res. Comm., 177: 652-658.
    • (1991) Biochem. Biophys. Res. Comm. , vol.177 , pp. 652-658
    • Muramatsu, H.1    Muramatsu, T.2
  • 37
    • 0027420495 scopus 로고
    • Midkine (MK), a retinoic acid-inducible growth/differentiation factor: Immunochemical evidence for the function and distribution
    • Muramatsu, H., Shirahama, H., Yonezawa, S., Maruta, H. and Muramatsu, T. (1993) Midkine (MK), a retinoic acid-inducible growth/differentiation factor: immunochemical evidence for the function and distribution. Dev. Biol., 159: 392-402.
    • (1993) Dev. Biol. , vol.159 , pp. 392-402
    • Muramatsu, H.1    Shirahama, H.2    Yonezawa, S.3    Maruta, H.4    Muramatsu, T.5
  • 38
    • 15844425959 scopus 로고    scopus 로고
    • Enzyme-linked immunoassay for midkine, and its application to evaluation of midkine levels in developing mouse brain and sera from patients with hepatocellulae carcinomas
    • Muramatsu, H., Song, X.-J., Koide, N., Hada, H., Tsuji, T., Kadomatsu, K., Inui, T., Kimura, T., Sakakibara, S. and Muramatsu, T. (1996) Enzyme-linked immunoassay for midkine, and its application to evaluation of midkine levels in developing mouse brain and sera from patients with hepatocellulae carcinomas. J. Biochem. (Tokyo), 119: 1171-1175.
    • (1996) J. Biochem. (Tokyo) , vol.119 , pp. 1171-1175
    • Muramatsu, H.1    Song, X.-J.2    Koide, N.3    Hada, H.4    Tsuji, T.5    Kadomatsu, K.6    Inui, T.7    Kimura, T.8    Sakakibara, S.9    Muramatsu, T.10
  • 39
    • 0028228479 scopus 로고
    • The midkine family of growth differentiation factors
    • Muramatsu, T. (1994) The midkine family of growth differentiation factors. Develop. Growth Differ., 36: 1-8.
    • (1994) Develop. Growth Differ. , vol.36 , pp. 1-8
    • Muramatsu, T.1
  • 40
    • 0023986985 scopus 로고
    • Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin βA chain
    • Murata, M., Eto, Y., Shibai, H., Sakai, M. and Muramatsu, M. (1988) Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin βA chain. Proc. Natl. Acad. Sci. USA., 85: 2434-2438.
    • (1988) Proc. Natl. Acad. Sci. USA. , vol.85 , pp. 2434-2438
    • Murata, M.1    Eto, Y.2    Shibai, H.3    Sakai, M.4    Muramatsu, M.5
  • 41
    • 0029904360 scopus 로고    scopus 로고
    • The angiogenic factor midkine is expressed in bladder cancer, and overexpression correlates with a poor outcome in patients with invasive cancers
    • O'Brien, T., Cranston, D., Fuggle, S., Bicknell, R. and Harris, A.L. (1996) The angiogenic factor midkine is expressed in bladder cancer, and overexpression correlates with a poor outcome in patients with invasive cancers. Cancer Res., 56: 2515-2518.
    • (1996) Cancer Res. , vol.56 , pp. 2515-2518
    • O'Brien, T.1    Cranston, D.2    Fuggle, S.3    Bicknell, R.4    Harris, A.L.5
  • 42
    • 0027688026 scopus 로고
    • Mapping the midkine family of develomentally regulated signaling molecules
    • Peichel, C.L., Scherer, S.W., Tsui, L.C., Beier, D.R. and Vogt, T.F. (1993) Mapping the midkine family of develomentally regulated signaling molecules. Mamm. Genome, 4: 632-438.
    • (1993) Mamm. Genome , vol.4 , pp. 632-438
    • Peichel, C.L.1    Scherer, S.W.2    Tsui, L.C.3    Beier, D.R.4    Vogt, T.F.5
  • 43
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • Petkovich, M., Brand, N.J., Krust, A. and Chambon, P. (1987) A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature, 330: 444-450.
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 44
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • Petkovich, M., Brand, N.J., Krust, A. and Chambon, P. (1987) A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature, 330: 444-450.
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 45
  • 46
    • 0026468785 scopus 로고
    • Chromosomal localization of two cell-surface associated molecules of potential importance in development: Midkine (Mdk) and basigin (Bsg)
    • Simon-Chazottes, D., Matsubara, S., Miyauchi, T., Muramatsu, T. and Guenet, J.L. (1992) Chromosomal localization of two cell-surface associated molecules of potential importance in development: midkine (Mdk) and basigin (Bsg). Mamm. Genome, 2: 269-271.
    • (1992) Mamm. Genome , vol.2 , pp. 269-271
    • Simon-Chazottes, D.1    Matsubara, S.2    Miyauchi, T.3    Muramatsu, T.4    Guenet, J.L.5
  • 47
    • 0023105348 scopus 로고
    • Mesoderm induction in early Xenopus embryos by heparin-binding growth factors
    • Slack, J.M., Darlington, B.G., Heath, J.K. and Godsave, S.F. (1987) Mesoderm induction in early Xenopus embryos by heparin-binding growth factors. Nature, 326: 197-200.
    • (1987) Nature , vol.326 , pp. 197-200
    • Slack, J.M.1    Darlington, B.G.2    Heath, J.K.3    Godsave, S.F.4
  • 48
    • 0018408665 scopus 로고
    • T98G: An anchorage-independent human tumor cell line that exhibits stationary phase G1 arrest in vitro
    • Stein, G.H., (1979) T98G: an anchorage-independent human tumor cell line that exhibits stationary phase G1 arrest in vitro. J. Cell Physiol., 99: 43-54.
    • (1979) J. Cell Physiol. , vol.99 , pp. 43-54
    • Stein, G.H.1
  • 49
    • 0018948184 scopus 로고
    • Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl CAMP
    • Strickland, S., Smith, K.K. and Marotti, K.R. (1980) Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl CAMP. Cell, 21: 347-355.
    • (1980) Cell , vol.21 , pp. 347-355
    • Strickland, S.1    Smith, K.K.2    Marotti, K.R.3
  • 51
    • 0030824409 scopus 로고    scopus 로고
    • Midkine, a retinoic acid-inducible beparin-binding cytokine in inflammatory responses: chemotactic activity to neutropbils and association with inflammatory synovitis
    • Takada, T., Toriyama, K., Muramatsu, H., Song, X.-J., Torii, S. and Muramatsu, T. (1997) Midkine, a retinoic acid-inducible beparin-binding cytokine in inflammatory responses: chemotactic activity to neutropbils and association with inflammatory synovitis. J. Biochem. (Tokyo), 122: 453-458.
    • (1997) J. Biochem. (Tokyo) , vol.122 , pp. 453-458
    • Takada, T.1    Toriyama, K.2    Muramatsu, H.3    Song, X.-J.4    Torii, S.5    Muramatsu, T.6
  • 52
    • 0023193801 scopus 로고
    • Identification and spatial distribution of retinoids in the developing chick limb bud
    • Thaller, C. and Eichele, G. (1987) Identification and spatial distribution of retinoids in the developing chick limb bud. Nature, 327: 625-628.
    • (1987) Nature , vol.327 , pp. 625-628
    • Thaller, C.1    Eichele, G.2
  • 53
    • 0025074908 scopus 로고
    • Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
    • Thomas, K.R. and Capecchi, M.R. (1990) Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature, 346: 847-850.
    • (1990) Nature , vol.346 , pp. 847-850
    • Thomas, K.R.1    Capecchi, M.R.2
  • 54
    • 0020316590 scopus 로고
    • Local application of retinoic acid to the limb bond mimics the action of the polarizing region
    • Tickle, C., Alberts, B., Wolpert, L. and Lee, J. (1982) Local application of retinoic acid to the limb bond mimics the action of the polarizing region. Nature, 296: 564-566.
    • (1982) Nature , vol.296 , pp. 564-566
    • Tickle, C.1    Alberts, B.2    Wolpert, L.3    Lee, J.4
  • 55
    • 0025316866 scopus 로고
    • A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product
    • Tomomura, M., Kadomatsu, K., Matsubara, S. and Muramatsu, T. (1990) A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product. J. Biol. Chem., 265: 10765-10770.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10765-10770
    • Tomomura, M.1    Kadomatsu K. Matsubara, S.2    Muramatsu, T.3
  • 56
    • 0027407537 scopus 로고
    • A new family of heparinbinding growth/differentiation factors: Increased midkine expression in Wilms' tumor and other human carcinomas
    • Tsutsui, J., Kadomatsu, K., Matsubara, S., Nakagawara, A., Hamanoue, M., Takao, S., Shimazu, H., Ohi, Y. and Muramatsu, T. (1993) A new family of heparinbinding growth/differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas. Cancer Res., 53: 1281-1285.
    • (1993) Cancer Res. , vol.53 , pp. 1281-1285
    • Tsutsui, J.1    Kadomatsu, K.2    Matsubara, S.3    Nakagawara, A.4    Hamanoue, M.5    Takao, S.6    Shimazu, H.7    Ohi, Y.8    Muramatsu, T.9
  • 57
    • 0025905831 scopus 로고
    • A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse
    • Tsutsui, J., Uehara, K., Kadomatsu, K., Matsubara, S. and Muramatsu, T. (1991) A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse. Biochem. Biophys. Res. Comm., 176: 792-797.
    • (1991) Biochem. Biophys. Res. Comm. , vol.176 , pp. 792-797
    • Tsutsui, J.1    Uehara, K.2    Kadomatsu, K.3    Matsubara, S.4    Muramatsu, T.5
  • 58
    • 0026536043 scopus 로고
    • Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor
    • Uehara, K., Matsubara, S., Kadomatsu, K., Tsutsui, J. and Muramatsu, T. (1992) Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor. J. Biochem. (Tokyo), 111: 563-567.
    • (1992) J. Biochem. (Tokyo) , vol.111 , pp. 563-567
    • Uehara, K.1    Matsubara, S.2    Kadomatsu K. Tsutsui, J.3    Muramatsu, T.4
  • 59
    • 0023756692 scopus 로고
    • Retinoic acid and thyroid hormone induce gene expression through a common responsive element
    • Umesono, K., Giguere, V., Glass, C.K., Rosenfeld, M.G. and Evans, R.M. (1988) Retinoic acid and thyroid hormone induce gene expression through a common responsive element. Nature, 336: 262-265.
    • (1988) Nature , vol.336 , pp. 262-265
    • Umesono, K.1    Giguere, V.2    Glass, C.K.3    Rosenfeld, M.G.4    Evans, R.M.5
  • 60
    • 0029070773 scopus 로고
    • Beneficial effect of a retinoic acid responsive gene product, midkine, on constant light-induced retinal damage in albino mice
    • (Japanese)
    • Unoki, K., Okubo, A., Arimura, H., Uehara, F., Muramatsu, H., Kadomatsu, K. and Muramatsu, T. (1995) Beneficial effect of a retinoic acid responsive gene product, midkine, on constant light-induced retinal damage in albino mice. Nippon Ganka Gakkai Zasshi, 99: 636-641. (Japanese)
    • (1995) Nippon Ganka Gakkai Zasshi , vol.99 , pp. 636-641
    • Unoki, K.1    Okubo, A.2    Arimura, H.3    Uehara, F.4    Muramatsu, H.5    Kadomatsu, K.6    Muramatsu, T.7
  • 61
    • 0030878420 scopus 로고    scopus 로고
    • Stimulation of collagen expression and glycosaminoglycan synthesis by midkine in human skin fibroblasts
    • Yamada, H., Inazumi, T., Tajima, S., Muramatsu, H. and Muramatsu, T. (1997) Stimulation of collagen expression and glycosaminoglycan synthesis by midkine in human skin fibroblasts. Arch. Dermatol. Res., 289: 429-433.
    • (1997) Arch. Dermatol. Res. , vol.289 , pp. 429-433
    • Yamada, H.1    Inazumi, T.2    Tajima, S.3    Muramatsu, H.4    Muramatsu, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.