Metabolism of butadiene by mice, rats, and humans: A comparison of physiologically based toxicokinetic model predictions and experimental data

Toxicology

Volumn 113, Issue 1-3, 1996, Pages 48-54

  Bond, James A ^d   Himmelstein, Matthew W ^a,d   Seaton, Mark ^b,d   Boogaard, Pieter ^c,d   Medinsky, Michele A ^d  

^a DUPONT COMPANY   (United States)

^b DOW CORNING CORPORATION   (United States)

^c SHELL RESEARCH AND TECHNOLOGY CENTRE   (Netherlands)

^d CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

1,3 butadiene; metabolism; physiologically based toxicokinetic models; risk assessment

Indexed keywords

1,3 BUTADIENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER RISK; CARCINOGENICITY; CONFERENCE PAPER; CONTROLLED STUDY; DOSIMETRY; HUMAN; HUMAN TISSUE; LIVER; LUNG; MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; TOXICOKINETICS; XENOBIOTIC METABOLISM;

ANIMALIA;

EID: 0012003987     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0300-483X(96)03426-9     Document Type: Conference Paper

References (24)

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