Optimization of Reaction Variables in the Selective Hydrodechlorination of Chlorinated Phthalic Anhydrides and Acids: Preparation of 3,6-Dichlorophthalic Acid and 3-Chlorophthalic Acid

Journal of Organic Chemistry

Volumn 58, Issue 1, 1993, Pages 261-263

  Fertel, Lawrence B ^a   O'Reilly, Neil J ^a   Callaghan, Kathleen M ^a  

^a Occidental Chemical Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0011919490     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo00053a050     Document Type: Note

References (11)

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2. For the use of 2 as a starting material for 2,4,5-trifluorobenzoic acid, a valuable quinolone intermediate, see: O'Reilly, N. J.; Derwin, W. S.; Fertel, L. B.; Lin, H. C. Synlett 1990, 609.
3. Villager, V. Chem. Ber. 1909, 42, 3529.
4. Zweig, A.; Epstein, M. J. Org. Chem. 1978, 43, 3690.
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7. Culhane, P. J.; Woodward, G. E. Organic Syntheses (Wiley: New York) 1941; Collect. Vol. I, p 408.
8. Nitration of N-alkyl phthalimides: Williams, F. J.; Donahue, P. E. J. Org. Chem. 1978, 43, 1608.
9. For an experimental procedure detailing the preparation of 2 from 1 see: O'Reilly, N. J.; Derwin, W. S.; Lin, H. C. Synlett 1990, 339.
10. Bergmann, E. D.; Bentov, M. J. Chem. Soc. 1964, 1194.
11. Neumann, R.; Scheuer, P. G. J. Am. Chem. Soc. 1956, 78, 5004.