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Tetrahedron Letters

Volumn 29, Issue 46, 1988, Pages 6013-6015

Synthesis of 1,2-dipalmitoyl-sn-glycer-3-yl-D-myo-inositol 1-phosphate.

(2) Ward, John G a Young, Rodney C a

a GLAXOSMITHKLINE (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0011835250 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4039(00)82254-6 Document Type: Article

Times cited : (37)

References (17)

1
- 0021750054
- (1984) Nature , vol.312 , pp. 315-321
- Berridge¹ Irvine²

2
- 84908733513
- P. Cohen, M. Houslay, Elsevier, North Holland
- (1985) Molecular Mechanisms of Transmembrane Signalling , pp. 3-56
- Downes¹ Michell²

3
- 0023897684
- (1988) Nature , vol.332 , pp. 644-646
- Whitman¹ Downes² Keeler³ Keller⁴ Cautley⁵

4
- 0019027018
- (1980) Chem. Phys. Lipids , vol.26 , pp. 287-404
- Gigg¹

5
- 84918479546
- 17 We thank Dr Martyn Voyle and Ms Lucy Hyatt, SK&F Welwyn, for supplying a sample of this compound. Its preparation will be described by these authors elsewhere.

6
- 37049090229
- Synthesis of myo-inositol 1-phosphate and 4-phosphate, and of their individual enantiomers
- (1987) Journal of the Chemical Society, Chemical Communications , pp. 314
- Billington¹ Baker² Kulagowski³ Mawer⁴

7
- 84918479545
- 3) 0.93 (3H, s), 1.01 (3H, s), 1.08 (9H, s), 1.09 (3H, s), 1.27 (3H, s), 1.34 (3H, s), 1.46 (3H, s), 1.60 (3H, s), 1.65 (1H, m), 1.89 (1H, m), 2.03 (1H, m), 2.43 (1H, m), 3.24 (1H, dd, J = 9.2, 11.1 Hz), 3.87 – 4.02 (3H, m), 4.15 (1H, dd, J = 9.5, 9.5 Hz), 5.33 (1H, dd, J = 6.4, 11.1 Hz), 7.34 – 7.47 (6H, m), 7.78 – 7.84 (4H, m).

8
- 84918479544
- 3) 1.07 (9H, s), 1.27 (3H, s), 1.42 (3H, s), 1.49 (3H, s), 1.55 (3H, s), 2.35 (1H, d, J=2.9 Hz), 3.13 (1H, m), 3.72 (1H, dd, J=4.8, 6.6 Hz), 3.82–3.94 (2H, M), 3.98–4.10 (2H, m), 7.33–7.47 (6H, m), 7.78–7.86 (4H, m).

9
- 0014740945
- (1970) Tetrahedron , vol.26 , pp. 1023
- Reese¹ Saffhill² Sulston³

10
- 84918479543
- 3) 1.07 (9H, s) 1.26 (3H, s), 1.36 (3H, s), 1.42 (3H, s) 1.58 (3H, s), 1.65–2.00 (4H, m), 3.11 (1H, dd, J=9.2, 10.5 Hz), 3.27 (3H, s), 3.55–3.58 (5H, m), 3.85–4.10 (4H, m), 7.30–7.50 (6H, m), 7.75–7.90 (4H, m).

11
- 84918479542
- +.

12
- 84918479541
- 2; 50:50) 0.87 (6H, t, J=6.3 Hz), 1.25 (48H, br.s), 1.51 (4H, m), 2.21 (4H, m), 3.88 (2H, m), 4.07 (1H, dd, J = 6.8, 11.9 Hz), 4.27 (1H, dd, J = 3.2, 11.9 Hz), 5.09 (1H, m), 6.89–6.96 (1H, m), 7.13 - 7.23 (4H, m).

13
- 0000405267
- (1980) Tetrahedron , vol.36 , pp. 3075
- Jones¹ Rayner² Reese³ Ubasawa⁴ Ubasawa⁵

14
- 84918479540
- 2) inter alia 0.88 (6H, t, J = 6.3 Hz), 1.68–1.83 (4H, m), 2.28 (4H, m), 3.25 and 3.26 (3H, 2xs), 3.36 (1H, dd, J = 10.2, 10.2 Hz), 3.48–3.63 (2H, m), 3.64–3.75 (2H, m), 3.98–4.20 (4H, m), 4.26–4.35 (3H, m), 4.43 and 4.58 (1H, 2xdd, in both cases J=4.5, 4.5 Hz), 4.67–4.82 (1H, m), 5.22 (1H, m), 7.18–7.38 (5H, m).

15
- 84918479539
- The inherent acidity of the intermediate phosphodiester was sufficient to effect this deprotection.

16
- 84918479538
- 6) 2.30.

17
- 0000162836
- (±)-1,2:4,5-Di-O-isopropylidene-myo-inositol
- (1985) Carbohydrate Research , vol.142 , pp. 132-134
- Gigg¹ Gigg² Payne³ Conants⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.