Auto-regulated osmotic pump for insulin therapy by sensing glucose concentration without energy supply

Sensors and Actuators, B: Chemical

Volumn 34, Issue 1-3, 1996, Pages 229-233

  Nagakura, Toshiaki ^a   Ishihara, Ken ^a   Furukawa, Toshiyuki ^a   Masuda, Kohji ^b   Tsuda, Takao ^b  

^a OSAKA NATIONAL HOSPITAL   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Blood sugar; Diabetes mellitus; Insulin pump; Mechanochemical actuator; Osmotic pump; Semipermeable membrane

Indexed keywords

EID: 0011396819     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4005(96)01954-5     Document Type: Article

References (4)

1. R.A. Siegel and B.A. Firestone, Progress toward an implantable, self-regulating, mechanochemical insulin pump, Proc. Int. Symp. Control Rel. Bioact. Mater., 15, 1988, pp. 164-165.
2. R.P. Durbin, Osmotic flow of water across permeable cellulose membranes, J. Gen. Physiol., 44 (1969) 315.
3. F.M.H. Villards and G.B. Bendek, Physics with illustrative example from medicine and biology, in Statistical Physics, Vol. 2, Addison-Wesley, MA, 1979, pp. 232-248.
4. K. Ishihara, T. Ueda and N. Nakabayashi, Preparation of phospholipid polymer and their properties as polymer hydrogel membranes, Polymer J., 22 (1990) 355-360.