Relative contribution of polar interactions and conformational compatibility to the binding of neurokinin-1 receptor antagonists

Molecular Pharmacology

Volumn 50, Issue 6, 1996, Pages 1605-1611

  Fong, Tung Ming ^a   Yu, Hong ^a   Huang, Ruey Ruey C ^a   Cascieri, Margaret A ^a   Swain, Christopher J ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 BENZHYDRYL 3 (2 METHOXYBENZYLAMINO) 1 AZABICYCLO[2.2.2]OCTANE; ALANINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DRUG ANALOG; GLUTAMINE; HISTIDINE; LIGAND; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CERCOPITHECIDAE; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; COS CELLS; CRICETINAE; HUMANS; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RECEPTORS, NEUROKININ-1; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0011119021     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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