The prophylactic effects of U75412E pretreatment in a smoke-induced lung injury rabbit model

Pharmacology and Toxicology

Volumn 79, Issue 5, 1996, Pages 231-237

  Wang, Shengjun ^a   Lantz, R Clark ^b,c   Chen, Guan Jie ^c   Breceda, Veronica ^a   Rider, Evelyn ^a   Hays, Allison M ^a   Parliman, Grace ^c   Tollinger, Brian J ^a   Robledo, Raymond F ^a,c   Kunke, Kathleen ^a   Tinajero, Julieta ^a   Witten, Mark L ^a,b,c  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Center for Toxicology   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LAZAROID; PROTECTIVE AGENT; TUMOR NECROSIS FACTOR ALPHA; U 75412E; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; INHALATIONAL DRUG ADMINISTRATION; LUNG ALVEOLUS MACROPHAGE; LUNG INJURY; LUNG LAVAGE; MODEL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOKE;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0010558803     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1996.tb00265.x     Document Type: Article

References (24)

1. Braughler, J. M., J. F. Pregenzer, R. L. Chase, L. A. Duncan, E. J. Jacobsen & J. M. McCall: Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation. J. Biol. Chem. 1987, 262, 10438-10440.
2. Brieland, J. K., R. G. Kunkel & J. C. Fantone: Pulmonary alveolar macrophages function during acute inflammatory lung injury. Amer. Rev. Respir. Dis. 1987, 135, 1300-1306.
3. Brieland, J. K., C. M. Flory, M. L. Jones, G. R. Miller, D. G. Remick, J. S. Warren & J. C. Fantone: Regulation of monocyte chemoattractant protein-1 gene expression and secretion in rat pulmonary alveolar macrophages by lipopolysaccharide, tumor necrosis factor-α, and interleukin-1β. Amer. J. Respir. Cell Mol. Biol. 1995, 12, 104-109.
4. Brinkmann, B. & K. Puschel: Heat injuries to the respiratory system. Virchows Arch. A Pathol. Anat. Histol. 1978, 379, 299-311.
5. DiGregorio, K. A., E. V. Cilento & R. C. Lantz: Measurement of Superoxide release from single pulmonary alveolar macrophages. Am. J. Physiol. 1987, 252, C677-C683.
6. Eskandari, M. K., D. T. Nguyen, S. L. Kunkel & D. G. Remick: WEHI 164 subclone 13 assay for TNF: sensitivity, specificity, and reliability. Immunol. Invest. 1990, 19, 69-79.
7. Espevik, T. & J. Nissen-Meyer: A highly sensitive cell line. WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Methods. 1986, 95, 99-105.
8. Hall, E. D., J. M. McCall & E. D. Means: Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv. Pharmacol. 1994, 28, 221-268 (Review).
9. Hays, A. M., R. C. Lantz, M. Vermeulen, G. Chen & M. L. Witten: U75412E pre-treatment before acute smoke exposure causes a large increase in lung prostacyclin concentrations. FASEB J. 1993, 7, A507.
10. Johnson, D., T Hurst, K. Prasad, T. Wilson, A. Saxena, F. Murphy & I. Mayers: Lazaroid pretreatment preserves gas exchange in endotoxin-treated dogs. J. Crit. Care 1994, 9, 213-223.
11. Kelley, J.: Cytokines of the lung. Amer. Rev. Respir. Dis. 1990, 141, 765-788 (Review).
12. Kojima, T., K. Hattori, T. Fujiwara, M. Sasai-Takedatsu & Y. Kobayashi: Meconium-induced lung injury mediated by activation of alveolar macrophages. Life Sci. 1994, 54, 1559-1562.
13. Li, X. Y., K. Donaldson, D. Brown & W. MacNee: The role of tumor necrosis factor in increased airspace epithelial permeability in acute lung inflammation. Amer. J. Respir. Cell Mol. Biol. 1995, 13, 185-195.
14. Linares, H. A., D. N. Herndon & D. L. Traber: Sequence of morphologic events in experimental smoke inhalation. J. Burn Care Rehabil. 1989, 10, 27-37.
15. Markley, K.: Burn care: infection and smoke inhalation. Ann. Intern. Med. 1979, 90, 269-270.
16. Moritz, A. R., F. C. Henriques & R. McLean: The effects of inhaled heat on the air passages and lungs. Amer. J. Pathol. 1945, 21, 311-325.
17. Myrvik, Q. N., E. S. Leake & B. Fariss: Studies on pulmonary alveolar macrophages from the normal rabbit: A technique to produce them in a high state of purity. J. Immunol. 1961, 86, 128-132.
18. Nath, K. A., J. Balla, A. J. Croatt & G. M. Vercellotti: Heme protein-mediated renal injury: a protective role for 21-aminosteroids in vitro and in vivo. Kidney Int. 1995, 47, 592-602.
19. Pinkerton, K. E. & J. D. Crapo: Morphometery of the alveolar region of the lung. In: Toxicology of inhaled materials. Eds.: H. P. Witschi and J. D. Brain. Springer-Verlag Publishers. 1985, P. 259-285.
20. Rider, E. D., M. L. Witten, R. C. Lantz, A. M. Hays & L. Dizon-Co: A free radical scavenger (Lazaroid U75412E) prevents smoke inhalation-induced changes in alveolar surfactant phospholipids. Amer. Rev. Respir. Dis. 1993, 147, A363.
21. Thompson, P., D. N. Herndon, S. Abston & T. Rutan: Effect of early excision on patients with major thermal injury. J. Trauma. 1987, 27, 205-207.
22. 99mTcDTPA lung clearance. Exp. Lung Res. 1990, 16, 339-353.
23. Witten, M. L., R. C. Lantz, R. Grad, S. Seidner, A. K. Hubbard, S. F. Quan, & R.J. Lemen: Effect of smoke inhalation on immediate changes in lung chemical mediators. Res. Commun. Chem. Pathol. Pharmacol. 1991, 74, 259-272.
24. Xing, Z., M. Jordana, H. Kirpalani, K. E. Driscoll, T. J. Schall, & J. Gauldie: Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-α, macrophage inflammatory protein-2. interleukin-1β, and interleukin-6 but not RANTES or transforming growth factor-β1 mRNA expression in acute lung inflammation. Amer. J. Respir. Cell Mol. Biol. 1994, 10, 148-153.