Chemistry of the anionically activated perfluoroalkyl group in heterocyclic synthesis

Heterocyclic Communications

Volumn 3, Issue 2, 1997, Pages 109-113

  Strekowski, Lucjan ^a   Lin, Shou Yuan ^a   Lee, Hyeran ^a   Wydra, Roman L ^a   Kiselyov, Alexander S ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0010522079     PISSN: 07930283     EISSN: None     Source Type: Journal    
DOI: 10.1515/HC.1997.3.2.109     Document Type: Article

References (9)

1. For recent reviews, see: (a) A.S. Kiselyov and L. Strekowski, Org. Prep. Proc. Int. 28, 289 (1996) (b) L. Strekowski and A.S. Kiselyov. Trends Heterocycl. Chem. 3, 73 (1993).
2. For recent reviews, see: (a) A.S. Kiselyov and L. Strekowski, Org. Prep. Proc. Int. 28, 289 (1996) (b) L. Strekowski and A.S. Kiselyov. Trends Heterocycl. Chem. 3, 73 (1993).
3. L Strekowski, S.-Y. Lin, H. Lee and J.C. Mason, Tetrahedron Lett. 37, 4655 (1996).
4. L. Strekowski, L. Janda, S.E. Patterson and J. Nguyen, Tetrahedron 52, 3273 (1996).
5. L Strekowski, Y. Gulevich, T.C. Baranowski, A.N. Parker, A.S. Kiselyov, S.-Y. Lin, F.A. Tanious and W.D. Wilson, J. Med. Chem. 39, 3980 (1996).
6. Compounds 1, 3 and 4 are commercially available (Aldrich). For synthesis of 2 and other perlluoroalkyl-substituted anilines, see: N. Yoshino, M. Kitamura, T. Seto, Y. Shibata, M. Abe and K. Ogino, Bull. Chem. Soc. Jpn. 65, 2141 (1992).
7. For the generation of heteroaryllithium reagents, see: L. Strekowski, D.B. Harden, W. Grubbs, S.E. Patterson, A. Czarny, M.J. Mokrosz, M.T. Cegla and R.L Wydra, J. Heterocycl. Chem. 27, 1393 (1990).
8. A.S. Kiselyov and L. Strekowski, Tetrahedron Lett. 35, 7597 (1994).
9. 19F NMR.