Amyloid β-peptide alters thrombin-induced calcium responses in cultured human neural cells

Amyloid

Volumn 3, Issue 1, 1996, Pages 28-40

  Mattson, Mark P ^a   Begley, James G ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; Antioxidants; Antisense; Free radicals; Fura 2; Human neuroblastoma SH SY5Y; Lipid peroxidation; Oligodeoxynucleotide; Protease nexin 1; Thiobarbituric acid; Amyloid precursor

Indexed keywords

EID: 0010232039     PISSN: 13506129     EISSN: None     Source Type: Journal    
DOI: 10.3109/13506129609014352     Document Type: Article

References (54)

1. Fenton II JW, Ofosu FA, Brezniak DV and Hassouna HI (1993). Understanding thrombin and hemostasis. Hematol Oncol Clin North Am 7, 1107-1119
2. Cunningham DD, Pulliam L and Vaughan PJ (1993). Protease nexin-1 and thrombin: injury related processes in the brain. Thromb Haemost 70, 168-171
3. 2+ homeostasis and sensitivity to glucose deprivation-induced injury. J Neurosci 15, 5840-5850
4. Ho GJ, Smirnova IV, Akaaboune M, Hantai D and Festoff BW (1994). Serine proteases and their serpin inhibitors in Alzheimer's disease. Biomed Pharmacother 48, 296-304
5. Weinstein J.R, Gold SJ, Cunningham DD and Gall CM (1995). Cellular localization of thrombin receptor mRNA in rat brain: expression by mesencephalic dopaminergic neurons and codistribution with prothrombin mRNA. J Neurosci 15, 2906-2919
6. Gurwitz D and Cunningham DD (1988). Thrombin modulates and reverses neuroblastoma neurite outgrowth. Proc Natl Acad Sci USA 85, 3440-3444.
7. Vauhan PJ, Pike CJ, Cotman CW and Cunningham DD (1995). Thrombin receptor activation protects neurons and astrocytes from cell death produced by environmental insults. J Neurosci 15, 5389-5401
8. Vu T-KH, Hung DT, Wheaton VI and Coughlin SR (1991). Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64, 1057-1068
9. 2+ mobilization, barrier dysfunction, prostaglandin synthesis and platelet-derived growth factor mRNA expression in cultured endothelium. J Cell Physiol 156, 541-549
10. Webb ML, Taylor DS and Molloy CJ (1993). Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. Biochem Pharmacol 45, 1577-1582
11. Mattson MP (1992). Calcium as sculptor and destroyer of neural circuitry. Exp Gerontology 27, 29-49
12. Siesjo BK (1994). Calcium-mediated processes in neuronal degeneration. Ann N Y Acad Sci 747, 140-161
13. Mattson MP (1994). Calcium and neuronal injury in Alzheimer's disease. Contributions of ß-amyloid precursor protein mismetabolism, free radicals and metabolic compromise. Ann NY Acad Sci 747, 50-76
14. Appel SH, Smith RG, Alexianu M, Engelhardt J, Mosier D, Colom L and Stefani E (1994). Neurodegenerative disease: autoimmunity involving calcium channels. Ann N Y Acad Sci 747, 183-194
15. Selkoe DJ (1993). Physiological production of the ß-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci 16, 403-409
16. Busciglio J, Lorenzo A and Yankner BA (1992). Methodological variables in the assessment of beta amyloid neurotoxicity. Neurobiol Aging 13, 609-612
17. Koh J-Y, Yang LL and Cotman CW (1990). ß-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res 533, 315-320
18. Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I and Rydel RE (1992). ß-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 12, 376-389
19. Pike CJ, Burdick D, Walencewicz AJ, Glabe CG and Cotman CW (1993). Neurodegeneration induced by amyloid ß-peptides in vitro: the role of peptide assembly state. J Neurosci 13, 1676-1687
20. Forloni G, Chiesa R, Smiroldo S and Verga L, (1993). Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35. Neuroreport 4, 523-526
21. Loo DT, Copani A, Pike CJ, Whittemore ER and Cotman CW (1993). Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci USA 90, 7951-7955
22. Goodman Y and Mattson MP (1994). Secreted forms of ß-amyloid precursor protein protect hippocampal neurons against amyloid ß-peptide-induced oxidative injury. Exp Neurol 128, 1-12
23. Goodman Y, Steiner MR, Steiner SM and Mattson MP (1994). Nordihydroguaiaretic acid protects hippocampal neurons against amyloid ß-peptide toxicity and attenuates free radical and calcium accumulation. Brain Res 654, 171-176
24. Hensley K, Carney JM, Mattson MP, Aksenova M, Harris M, Wu JF, Floyd R and Butterfield DA (1994). A model for ß-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer's disease. Proc Natl Acad Sci USA, 91, 3270-3274
25. Butterfield DA, Hensley K, Harris M, Mattson MP and Carney JM (1994). ß-amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease. Biochem Biophys Res Commun 200, 710-715
26. Behl C, Davis JB, Lesley R and Schubert D (1994). Hydrogen peroxide mediates amyloid ß protein toxicity. Cell 77, 817-827
27. 2+ homeostasis and cell death. J Neurosci 15, 6239-6249
28. Hartmann H, Eckert A, and Muller WE (1993). ß-amyloid protein amplifies calcium signalling in central neurons from the adult mouse. Biochem Biophys Res Commun 194, 1216-1220
29. Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA and Markesbery WR (1991). Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer's disease. Proc Natl Acad Sci USA 88, 10540-10543
30. Flynn DD, Ferrari-Dileo G, Mash DC and Levey AI (1995). Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J Neurochem 64, 1888-1891
31. Warpman U, Alafuzoff I and Nordberg A (1993). Coupling of muscarinic receptors to GTP proteins in postmortem human brain - alterations in Alzheimer's disease. Neurosci Lett 150, 39-43
32. Kelly JF, Furukawa K, Barger SW, Rengen MR, Rothe GS and Mattson MP (1995). Amyloid ß-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons. Soc Neurosci Abstr 21, 480
33. Cheng B and Mattson MP (1995). PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways. J Neurosci 15, In press
34. Brass LF, Pizarro S, Ahuja M, Belmonte E, Blanchard N, Stadel JM and Hoxie JA (1994). Changes in the structure and function of the human thrombin receptor during receptor activation, internalization and recycling. J Biol Chem 269, 2943-2952
35. Mattson MP, Barger SW, Begley JG and Mark RJ (1995). Calcium, free radicals and excitotoxic neuronal death in primary cell culture. Meth Cell Biol 46, 187-216
36. Juurlink BHJ and Husain J (1994). Hyperthermic injury of oligodendrocyte precursor cells: implications for dysmyelination disorders. Brain Res 641, 353-356
37. White BC, Daya A, Degracia DJ, Oneil BJ, Skaerlund JM, Trumble S, Krause GS and Rafols JA (1993). Fluorescent histochemical localization of lipid peroxidation during brain reperfusion following cardiac arrest. Acta Neuropathol 86, 1-9
38. Suidan HS, Stone SR, Hemmings BA and Monard D (1992). Thrombin causes neunte retraction in neuronal cells through activation of cell surface receptors. Neuron 8, 363-375
39. Lapetina EG (1990). The signal transduction induced by thrombin in human platelets. FEBS Lett 268, 400-412
40. Berk BC, Taubman MB, Griendling KK, Cragoe EJ, Fenton II JW and Brock TA (1991). Thrombin-stimulated events in cultured vascular smooth muscle cells. Biochem J 272, 799-805
41. Tordai A, Fenton II JW, Andersen T and Gelfand EW (1993). Functional thrombin receptors on human T lymphoblastoid cells. J Immunol. 150, 4876-4886
42. Monard D, Niday E, Limat A and Solomon F (1983). Inhibition of protease activity can lead to neurite extension in neuroblastoma cells. Prog Brain Res 58, 359-364
43. Liu Y, Fields RD, Festoff BW and Nelson PG (1994). Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction. Proc Natl Acad Sci USA 91, 10300-10304
44. Houenou LJ, Turner PL, Li L, Oppenheim RW and Festoff BW (1995). A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death. Proc Natl Acad Sci USA 92, 895-899
45. Rich KM (1992). Neuronal death after trophic factor deprivation. J Neurotrauma 9, S61-S69
46. Cheng B and Mattson MP (1992). IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage. J Neurosci 12, 1558-1566
47. Fukuyama R, Wadhwani KC, Galdzicki Z, Rapoport SI and Ehrenstein G (1994). ß-amyloid polypeptide increases calcium-uptake in PC12 cells: a possible mechanism for its cellular toxicity in Alzheimer's disease. Brain Res 667, 269-272
48. Cowburn RF, O'Neil C, Ravid R, Alafuzoff I, Winblad B and Fowler CJ (1992). Adenylate cyclase activity in postmortem human brain: evidence of altered G protein mediation in Alzheimer's disease. J Neurochem 58, 1409-1419
49. Ross BM, McLaughlin M, Roberts M, Milligan G, McCulloch J and Knowler JT (1993). Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease. Brain Res 622, 35-42.
50. Akiyama H, Skeda K, Kondo H and McGreer PL (1992). Thrombin accumulation in brains of patients with Alzheimer's disease. Neurosci Lett 146, 152-154
51. Choi BH, Kim RC, Vaughan PJ, Lau A, Van Nostrand WE, Cotman CW and Cunningham DD (1995). Decreases in protease nexins in Alzheimer's disease brain. Neurobiol Aging 16, 557-562
52. Smith-Swintosky VL, Zimmer S, Fenton II JW and Mattson MP (1995). Opposing actions of thrombin and protease nexin-1 on amyloid ß-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons. J Neurochem 65, 1415-1418
53. Bolkenius FN and Monard D (1995). Inactivation of protease nexin-1 by xanthine oxidase-derived free radicals. Neurochem Int 26, 587-592.
54. Mattson MP and Goodman Y (1995) Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium. Brain Res 676, 219-224