Synthesis, Vasodilating and Antithrombotic Activity of Pyridyl-substituted Silylisoxazolines

Applied Organometallic Chemistry

Volumn 11, Issue 10-11, 1997, Pages 805-811

  Lukevics, E ^a   Veveris, M ^a   Dirnens, V ^a  

^a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

Author keywords

Acute toxicity; Antithrombotic properties; Haemodynamic parameters; Pyridyl nitrile oxide; Silatrane; Silylisoxazolines; Vasodilating; Vinylsilane; 2+3 cycloaddition reaction

Indexed keywords

EID: 0010181955     PISSN: 02682605     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0739(199710/11)11:10/11<805::AID-AOC637>3.0.CO;2-E     Document Type: Article

References (20)

1. A. S. O. Adeagbo and C. R. Triggle, J. Cardiovasc. Pharmacol. 21, 423 (1993).
2. H. Drexler and B. Horning, J. Cardiovasc. Pharmacol. 27, 9 (1996).
3. E. Bungardt, E. Vockert, R. Feifel, U. Moser, R. Tacke, E. Mutschler, G. Lambrecht and A. Surprenant, Eur. J. Pharmacol. 213, 53 (1992).
4. E. Barocelli, M. Chiavarini, V. Ballabeni, F. Bordi and M. Impicciatore, Br. J. Pharmacol. 108, 393 (1993).
5. R. Paul and S. Tchelitcheff, Bull. Soc. Chim. Fr. 2215 (1962).
6. M. Kocevar, S. Polanc, M. Sollner, M. Tisler and B. Vercek, Synth. Commun. 18, 1427 (1988).
7. R. Blattner, H. G. Classen, H. Dehnert and H. G. Doring, Experiments on Isolated Smooth Muscle Preparations, Hugo Sachs Elektronik KG, (BRD), 1980.
8. S. K. Wilson, O. S. Steinsland and S. H. Nelson, J. Cardiovasc. Pharmacol. 23, 127 (1994).
9. Y. Thodorov, Klinischeskie Laboratornye Issledovania v Pediatrii. Medic. Phys., Sophia, 1966.
10. J. A. Michell, U. Forstermann, T. D. Warnen, J. S. Pollock, H. H. Schmidt, M. Hellen and F. Murad, Biochem. Biophys. Res. Commun. 176, 14 (1991).
11. L. J. Ignarro, Hypertension 16, 477 (1990).
12. R. F. Furchgott and J. V. Zawadzki, Nature (London) 288, 373 (1980).
13. R. F. Furchgott, Circ. Res. 53, 557 (1983).
14. R. M. J. Palmer, A. G. Ferige and S. Moncada, Nature (London) 327, 524 (1987).
15. R. M. J. Palmer, D. D. Rees, D. S. Ashton and S. Moncada, Biochem. Biophys. Res. Commun. 153, 1251 (1988).
16. I. Sakuma, D. Stuehr, S. S. Gross, C. Nathan and R. Levi, Proc. Natl. Acad. Sci. USA 85, 8664 (1988).
17. A. R. Butter and D. Z. H. Williams, Chem. Soc. Rev., 233 (1993).
18. M. G. Doni, A. Alexandre, E. Tadoin, S. Bertoncello and R. Deana, Cardioscience 2(3), 161 (1991).
19. R. Soyka, A. Heckel, J. Nickl, W. Eisert, T. H. Muller and H. Weisenberger, J. Med. Chem. 37 , 26 (1994).
20. M. Hecker, M. Haurand, V. Ulrich and S. Terao, Eur. J. Biochem. 157, 217 (1986).