Analysis of binding domain and function of chimeric μ/κ opioid receptors to ohmefentanyl stereoisomers

Acta Pharmacologica Sinica

Volumn 22, Issue 11, 2001, Pages 981-985

  Feng, Ya Ping ^a   Chen, Li Wei ^a   Zhou, De He ^a   Chen, Jie ^a   Xu, Xue Jun ^a   Chi, Zhi Qiang ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Binding sites; COS 1 cell line; Cyclic AMP; Kappa opioid receptors; mu opioid receptors; Ohmefentanyl; Stereoisomerism; U50488

Indexed keywords

3,4 DICHLORO N METHYL N (2 (1 PYRROLIDINYL) CYCLOHEXYL) BENZENEACETAMIDE, (TRANS) ISOMER; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; ANALGESIC AGENT; BETA HYDROXYMEFENTANYL; CHIMERIC PROTEIN; CYCLIC AMP; DRUG DERIVATIVE; DYNORPHIN; DYNORPHIN A (1 9); DYNORPHIN[1-9]; FENTANYL; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; PEPTIDE FRAGMENT;

ANIMAL; ARTICLE; BINDING SITE; CELL STRAIN COS1; CERCOPITHECUS; METABOLISM; PROTEIN TERTIARY STRUCTURE; STEREOISOMERISM;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS; ANIMAL; BINDING SITES; CERCOPITHECUS AETHIOPS; CHIMERIC PROTEINS; COS CELLS; CYCLIC AMP; DYNORPHINS; FENTANYL; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; STEREOISOMERISM; SUPPORT, NON-U.S. GOV'T;

EID: 0009974781     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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