Diagnostic value of p53 protein and flow cytometric DNA analysis in the study of serous effusions

Acta Cytologica

Volumn 41, Issue 6, 1997, Pages 1719-1725

  Lee, Ji Shin ^a   Lee, Min Cheol ^a   Park, Chang Soo ^a   Juhng, Sang Woo ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CYTOKERATIN; EPITHELIAL MEMBRANE ANTIGEN; FIBRONECTIN; PROTEIN P53;

ARTICLE; CELL POPULATION; CYTOLOGY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DNA CONTENT; DNA DETERMINATION; EFFUSION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LABORATORY TEST; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL;

EID: 0009534549     PISSN: 00015547     EISSN: 19382650     Source Type: Journal    
DOI: 10.1159/000333175     Document Type: Article

References (35)

1. Athanassiadou P, Athanassiades P, Lazaris D, Kyrkou K, Pe-trakakou E, Aravantinos D: Immunocytochemical differentiation of reactive mesothelial cells and adenocarcinoma cells in serous effusions with the use of carcinoembryonic antigen and fibronectin. Acta Cytol 1993;38:718-722
2. Barlogie B: Abnormal cellular DNA content as a marker of neoplasia. Eur J Cancer Clin Oncol 1984;20:1123-1125
3. Barlogie N, Drewinko B, Schumann J, Gohde W, Dosik G, La-treille J, Johnston DA, Freireich EJ: Cellular DNA content as a marker of neoplasia in man. Am J Med 1980;69:195-203
4. Barlogie B, Raber MN, Schumann J, Johnson TS, Drewinko B, Swartzendruber DE, Gohde W, Andreeff M, Freireich EJ: Flow cytometry in clinical cancer research. Cancer Res 1983; 43:3982-3997
5. Cattoretti G, Rilke F, Andreola S, D'Amato L, Delia D: p53 Expression in breast cancer. Int J Cancer 1988;41:178-183
6. Chang K, Ding I, Kern FG, Willingham MC: Immunohisto-chemical analysis of p53 and HER-2/neu proteins in human tumors. J Histochem Cytochem 1991;39:1281-1287
7. Coon JS, Landay AL, Weinstein RS: Biology of disease: Advances in flow cytometry for diagnostic pathology. Lab Invest 1987;57:453-479
8. Dewald G, Dines DE, Weiland LH, Gordon H: Usefulness of chromosome analysis in the diagnosis of malignant pleural effusions. N Engl J Med 1976;295:1494-1500
9. El-Habashi A, El-Morsi B, Freeman SM, El-Didi M, Marrogi AJ: Tumor oncogenic expression in malignant effusions as a possible method to enhance cytologic diagnostic sensitivity: An immuocytochemical study of 87 cases. Am J Clin Pathol 1995;103:206-214
10. Frankfurt OS, Slocum HK, Rustum YM, Arbuch SG, Pavelic ZP, Petrelli N, Huben RP, Pontes EJ, Greco WR: Flow cytometric analysis of DNA aneuploidy in primary and metastatic human solid tumors. Cytometry 1984;5:71-80
11. Hollstein M, Sidransky D, Vogelstein B, Harris C: p53 Mutations in human cancers. Science 1991;253:49-53
12. Hsu SM, Raine L, Fanger H: A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am J Clin Pathol 1981;75:734-738
13. Huang MS, Tsai MS, Hwang JJ, Wang TH: Comparison of nucleolar organizer regions and DNA flow cytometry in the evaluation of pleural effusion. Thorax 1994;49:1152-1156
14. Jones MA, Hitchcox S, D'Ascanio P, Papillo J, Tarraza HM: Flow cytometric DNA analysis versus cytology in the evaluation of peritoneal fluids. Gynecol Oncol 1991;43:226-232
15. Kehoe S, Ward K, Luesley D, Chan KK: The application of flow cytometric DNA analysis in detecting the presence of malignant cells in ovarian carcinoma peritoneal fluids. Br J Obstet Gynaecol 1995;102:656-659
16. Kern S, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B: Oncogenic forms of p53 inhibit p53-regulated gene expression. Science 1992;256:827-830
17. Koss LG: Diagnostic Cytology and Its Histopathologic Bases. Philadelphia, JB Lippincott, 1979, p 921
18. Koss LG, Czerniak B, Herz F, Wersto RP: Flow cytometric measurement of DNA and other cell components in human tumors: A critical appraisal. Hum Pathol 1989;20:528-548
19. Lee JS, Nam JH, Lee MC, Park CS, Juhng SW: Immunohisto-chemical panel for distinction carcinoma cells and reactive mesothelial cells in serous effusions. Acta Cytol 1996;40:631-636
20. Marshall C: Tumor suppressor gene. Cell 1991;64:313-326
21. Mezger J, Stotzer O, Schilli G, Bauer S, Wilmanns W: Identification of carcinoma cells in ascitic and pleural fluid: Comparison of four panepithelial antigens with carcinoembryon-ic antigen. Acta Cytol 1992;36:75-81
22. Reed JA, Manahan LJ, Park CS, Brigati DK: Complete one-hour immunohistochemistry based on capillary action. Biotechniques 1992;13:434-443
23. Rijken A, Dekker A, Taylor S, Hoffman P, Blank M, Krause JR: Diagnostic value of DNA analysis in effusions by flow cytometry and image analysis: A prospective study on 102 patients as compared with cytologic examination. Am J Clin Pathol 1991;95:6-12
24. Rotmensch J, Atcher BW, Schwartz JL, Grdina DJ: Analysis of ascites from patients with ovarian carcinoma by cell flow cytometry. Gynecol Oncol 1992;44:10-12
25. Scott N, Sagar P, Stewart J, Blair GE, Dixon MF, Quirke P: p53 In colorectal cancer: Clinicopathological correlation and prognostic significance. Br J Cancer 1991;63:317-319
26. Singh G, Dekker A, Ladoulis CT: Tissue culture of cells in serous effusions: Evaluation as an adjunct to cytology. Acta Cytol 1978;22:487-489
27. Sinton EB, Carver RK, Morgan DL, Philpott PJ, Truell JE, Rie-mann D, Ashton ME: Prospective study of concurrent ploidy analysis and routine cytopathology in body cavity fluids. Arch Pathol Lab Med 1990;114:188-194
28. Stonesifer KJ, Xiang JH, Wilkinson E, Benson NA, Braylan RC: Flow cytometric analysis and cytopathology of body cavity fluids. Acta Cytol 1987;31:125-130
29. Vindelov LL, Christensen IJ, Nissen NI: A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 1983;3:323-327
30. Vogelstein B: Genetic alterations in colorectal tumors. Adv Oncol 1991;7:3-6
31. Walts AE, Said JW, Koeffler HP: Is immunoreactivity for p53 useful in distinguishing benign from malignant effusions?: Localization of p53 gene product in benign mesothelial and adenocarcinoma cells. Mod Pathol 1994;7:462-468
32. Weissman GS, McKinley MJ, Budman DR, Cacces WJ, Schul-man P, Grueneberg D, Bronzo RL: Flow cytometry: A new technique in diagnosis of malignant ascites. J Clin Gastroenterol 1987;9:599-602
33. Whiteside TL, Dekker A: Diagnostic significance of carcino-embryonic antigen levels in serous effusions: Correlation with cytology. Acta Cytol 1979;23:443-448
34. Zarbo R: Flow cytometric DNA analysis of effusions: A new test seeking validation. Am J Clin Pathol 1991;95:2-4
35. Zoppi JA, Pellicer E, Sundblad A: Diagnostic value of p53 protein in the study of serous effusions. Acta Cytol 1995;39: 721-724