Phosphorylation signals of the insulin receptor in human red cells: Activation of Na+/H+ exchange

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 7, Issue 2, 1997, Pages 57-62

  Canessa, M ^a   Manriquez E ^a,b  

^a UNIVERSITY OF CHILE   (Chile)

^b NONE   (Chile)

Author keywords

Insulin; Na+ H+ exchange; S T phosphorylation; Tyrosine phosphorylation

Indexed keywords

EID: 0009457859     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. + countertransport in red cells of patient with essential hypertension. N Engl J Med 302: 772-776
2. + exchanger. J Membrane Biol 107: 219-228
3. + exchange pathways. J Membrane Biol 118: 193-214
4. + exchanger in essential hypertension. J Cardiovasc Pharmacol 12: 92-98
5. + countertransport in hypertension. In: Coca A, Garay R, (Eds) Ionic transport in hypertension: New perspectives. CRC Press, Boca Raton, FL, pp 90-117
6. + exchange system. J Membrane Biol 90: 21-28
7. Canessa M, Morgan K, Goldszer R, Moore JT, Spalvins A (1991) Kinetic abnormalities of the red blood cells sodium-proton exchange in hypertensive patients. Hypertension 17: 340-348
8. Canessa M, Falkner B, and Hulman S (1993) Red blood cells sodium-proton exchange in hypertensive blacks with insulin resistant glucose disposal. Hypertension 22: 204-213
9. + countertransport in essential hypertension. Am J Physiol 261: E684-E691
10. + countertransport activity and total body insulin-mediated glucose disposal in normalbuminuric normotensive type I (insulin-dependent) diabetic patients. Diabetologia 36: 52-56
11. Krowleski AS, Canessa M, Warram JH, Lafell LMB, Christlieb AR, Knower W, Rand LI (1988) Predisposition to hypertension and susceptibility to renal disease in insulin-dependent diabetes mellitus. N Engl J Med 318: 140-145
12. + antiport activity and abundance in uremic red bloods cells. Kidney Int 44: 574-578
13. + exchange. CRC Press, Boca Raton, Fla
14. Grigorescu F, White MF, Kahn SR (1983) Insulin binding and insulin-dependent phosphorylation of the insulin receptor solubilized from human erythrocytes. J Biol Chem 258: 13708-13716
15. Gambhir KK, Archer JA, Bradley CJ (1978) Insulin radioceptor assay for human erythrocytes. Diabetes 27: 701-78
16. + exchange decreases the affinity of sodium sites. Kidney Int 46: 365-375
17. + antiporter, a glycoprotein of 110 kD. Science 247: 723-726
18. Coligan J, Kruisbeek A, Margulies D, Shevach E, Straber W. (1994) Current Protocols in Immunology. John Wiley & Sons
19. 2+-dependent phosphorylation of human red cells membrane skeletal proteins. J Biol Chem 261: 7701-7709
20. Laemmli UK (1970) Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature (London) 227: 680-685
21. Towbin H, Staehlin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76:4350-4354
22. Clari G, Marzaro G, and Moret V (1990) Metabolic depletion effect on serine/threonine- and tyrosine-phosphorylations of membrane proteins in human erythrocytes. Biochim Biophys Acta 1023: 319-324
23. Zerbini G, Ceolotto G, Gaboury C, Mos L, Pessina AC, Canessa M, Semplicini A (1995) Sodium-lithium countertransport has low affinity for sodium in hyperinsulinemic hypertensive subjects. Hypertension 986-993
24. Ceolotto G, Conlin P, Clari G, Romero J, Semplicini A, Canessa M (1997) Protein kinase C and insulin regulations of red blood cell sodium-proton exchange. Am J Physiol 272: C41; in press
25. + exchanger isoforms. Am J Physiol 268 (Cell Physiol 37): C283-C296
26. + antiport. J Biol Chem 266: 15406-15413
27. Kahn CR (1994) Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 43: 1066-1083
28. White MF, Maron R, and Kahn CR (1985) Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185.000 protein in intact cells. Nature 318: 183-186
29. Ortolani D, Muñoz P, Bize I, Canessa M (1996) Insulin stimulates phosphorylation of the human red cell cytoskeletal proteins. X Annual Meeting of the Sociedad de Biología Celular. Termas de Cauquenes, Chile
30. + exchanger isoform NHE-1 and NHE-3 exist as stable dimers in membranes with a high degree of specificity for monodimers. J Biol Chem 269: 258-2596
31. + exchanger, NHE-1, by phosphorylating a set of common sites. J Biol Chem 266: 19166-19171
32. + antiport. J Biol Chem 259:5809-5815