Pulsed ultrafiltration: A new method for screening and measuring ligand binding

American Laboratory

Volumn 30, Issue 24, 1998, Pages 16-19

  Woodbury, Charles P ^a   Venton, Duane L ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0008556185     PISSN: 00447749     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Article

References (9)

1. Winzor DJ, Sawyer WH. Quantitative characterization of ligand binding. New York: Wiley-Liss, 1995.
2. Connors KA. Binding constants. The measurement of molecular complex stability. New York: Wiley-Interscience, 1987.
3. Hulme EC. Receptor-ligand interactions, a practical approach. Oxford, U.K.: IRL Press, 1992.
4. Klotz IM. Ligand-receptor energetics, a guide for the perplexed. New York, NY: John Wiley and Sons, 1997.
5. Van Breemen RB, Huang C-R, Nikolic F, Woodbury CP, Venton DL. Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries. Anal Chem 1997; 69:2159-64.
6. Zhao YZ, Van Breemen RB, Nikolic D, Huang C-R, Woodbury CP, Venton DL. Screening solution-phase combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry. J Med Chem 1997; 40:4006-12.
7. Chen C-J, Chen S, Woodbury CP, Venton DL. Pulsed ultrafiltration characterization of binding I: a new method. Anal Biochem 1998; 261:164-82.
8. Richards FM, Wyckoff HW. Bovine pancreatic ribonuclease. In: Boyer PD, ed.: The enzymes, vol IV. New York: Academic Press, 1971.
9. Wiseman T, Williston S, Brandts JF, Lin L-N. Rapid measurement of binding constants and heats of binding using a new titration calorimeter. Anal Biochem 1989; 179:131-7.