Tryptophan reaction with free radicals arisen from carbon tetrachloride in a model system. A mass spectrometric study

Redox Report

Volumn 2, Issue 1, 1996, Pages 47-54

  Castro, G D ^a   Castro, J A ^a  

^a Instituto de Investigaciones Cientificas y Tecnicas de Las Fuerzas Armadas   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0008271494     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1080/13510002.1996.11747026     Document Type: Article

References (19)

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4. Trudell J R, Bösterling R, Trevor A J. Reductive metabolism of carbon tetrachloride by human cytochrome P450 reconstituted in phospholipid vesicles: Mass spectral identification of trichloromethyl radicals bound to dioleyl phosphatidyl choline. Proc Natl Acad Sci USA 1982; 79: 2678-2686.
5. Wilson R L. Organic peroxy free radicals as ultimate agents in oxygen toxicity. In: Sies H, (ed.) Oxidative Stress, New York: Academic Press, 1985: 41-72.
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7. Halliwell B, Gutteridge J M C. In: Free radicals in biology and medicine, 2nd ed. Oxford: Clarendon Press, 1989: 22-85.
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9. Castro J A, Diaz Gómez M I, Ferreyra E C de, Castro C R de, D'Acosta N, Fenos O M de. Differences in the carbon tetrachloride induced damage to components of the smooth and rough endoplasmic reticulum from rat liver. Biochem Biophys Res Commun 1973; 50: 337-343.
10. 4 reactive metabolites and liver DNA and nuclear protein fractions. Carcinogenesis 1989; 10: 289-294.
11. 4 to liver microsomal lipids and proteins from rats pretreated with compounds altering microsomal mixed function oxygenase activity. Toxicol Appl Pharmacol 1973; 25: 534-541.
12. Diaz Gómez M I, Castro J A. Covalent binding of carbon tetrachloride metabolites to liver nuclear DNA, proteins and lipids. Toxicol Appl Pharmacol 1980; 56: 199-206.
13. Fraenkel-Conrat H. Other reactive group of enzymes. In: Boyer P O, Lardy H, Myrbäck K, (eds.) The enzymes, vol 1. New York: Academic Press, 1959: 608-613.
14. Dixon M, Webb E C. Enzymes, 3rd ed. New York: Academic Press, 1979: 304-569.
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16. Uchida K, Enomoto N, Itakura K, Kawasaki S. Formation of diastereoisomeric 3a-hydroxypyrroloindoles from a tryptophan residue analog mediated by iron (H)-EDTA and 1- ascorbate. Arch Biochem Biophys 1990; 279: 14-20.
17. Castro G D, Díaz Gómez M I, Castro J A. Interaction of trichloromethyl free radicals with phenylalanine. Arch Toxicol 1991; 65: 340-343.
18. Castro G D, Stamato C J, Castro J A. Tyrosine attack by free radicals derived from catalytic decomposition of carbon tetrachloride. Free Radie Biol Med 1994; 16: 693-701.
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