메뉴 건너뛰기




Volumn 44, Issue 14, 1999, Pages 1257-1264

Development in the research of molecular mechanism of Alzheimer's disease

Author keywords

Alzheimer's disease; Apoliporprotein E; Neurofibrillary tangles; Presenlin; Proteinaceous infectious particles; Senile plaque; Tau protein; Amyloid

Indexed keywords


EID: 0007982238     PISSN: 10016538     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02885840     Document Type: Review
Times cited : (1)

References (31)
  • 1
    • 0021207461 scopus 로고
    • Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
    • Glenner, G. G., Wong, C. W., Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein, Biochem. Biophys. Res. Commun., 1984, 122: 1131.
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 1131
    • Glenner, G.G.1    Wong, C.W.2
  • 2
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
    • Kang, J., Lemaire, H. G., Vnterbeck, E. et al., The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor, Nature, 1987, 325: 733.
    • (1987) Nature , vol.325 , pp. 733
    • Kang, J.1    Lemaire, H.G.2    Vnterbeck, E.3
  • 3
    • 0027407570 scopus 로고
    • Bener action of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells
    • Busciglo, J., Gabuzda, D., Matsudeira, P. et al., Bener action of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells, Proc. Natl. Acad. Sci. USA, 1993, 90: 2092.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2092
    • Busciglo, J.1    Gabuzda, D.2    Matsudeira, P.3
  • 4
    • 0027459686 scopus 로고
    • Seeretion of beta-amyloid peptide
    • Seubert, P., Oltersdorf, T., Lee, M. et al., Seeretion of beta-amyloid peptide, Nature, 1993, 361: 260.
    • (1993) Nature , vol.361 , pp. 260
    • Seubert, P.1    Oltersdorf, T.2    Lee, M.3
  • 5
    • 0025295039 scopus 로고
    • Cleavage of amyloid-β peptide during constitutive processing of its precursor
    • Esch, F. S., Keim, P. S., Beattle, E. C. et al., Cleavage of amyloid-β peptide during constitutive processing of its precursor, Science, 1990, 248: 1122.
    • (1990) Science , vol.248 , pp. 1122
    • Esch, F.S.1    Keim, P.S.2    Beattle, E.C.3
  • 6
    • 0028322017 scopus 로고
    • An increased percentage of long amyloid betaprotein secreted by familial amyloid beta-protein precussor (beta-APP717) mutants
    • Suzuki, N., Cheung, T. T., Cai, X. D. et al., An increased percentage of long amyloid betaprotein secreted by familial amyloid beta-protein precussor (beta-APP717) mutants, Science, 1994, 264: 1336.
    • (1994) Science , vol.264 , pp. 1336
    • Suzuki, N.1    Cheung, T.T.2    Cai, X.D.3
  • 7
    • 0026088977 scopus 로고
    • Segregation of amissense mutation in the amyloid precursor protein gene with familiar AD
    • Goate, A. M., Chartier-Harlin, M, C., Mullan, M. et al., Segregation of amissense mutation in the amyloid precursor protein gene with familiar AD, Nature, 1991, 349: 702.
    • (1991) Nature , vol.349 , pp. 702
    • Goate, A.M.1    Chartier-Harlin, M.C.2    Mullan, M.3
  • 8
    • 0026075602 scopus 로고
    • An early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene
    • Chartier-Harlin, M. C., Crawford, F., Houlden, H. et al., An early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene, Nature, 1991, 353: 384.
    • (1991) Nature , vol.353 , pp. 384
    • Chartier-Harlin, M.C.1    Crawford, F.2    Houlden, H.3
  • 9
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpression B717F β-amyloid precursor protein
    • Games, D., Adams, D., Alessandrini, R. et al., Alzheimer-type neuropathology in transgenic mice overexpression B717F β-amyloid precursor protein, Nature, 1995, 373: 523.
    • (1995) Nature , vol.373 , pp. 523
    • Games, D.1    Adams, D.2    Alessandrini, R.3
  • 10
    • 0027526419 scopus 로고
    • Release of excess amyloid beta-protein from emutant amyloid beta protein precursor
    • Cai, X. D., Golde, T., Youndin, S., Release of excess amyloid beta-protein from emutant amyloid beta protein precursor, Science, 1993, 254: 514.
    • (1993) Science , vol.254 , pp. 514
    • Cai, X.D.1    Golde, T.2    Youndin, S.3
  • 11
    • 0026443727 scopus 로고
    • Deposition of beta-A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxylterminal fragment of the Alzheimer amyloid precursor in the brain
    • Kammessheidt, E., Boyce, F., Spanoyan, S. et al., Deposition of beta-A4 immunoreactivity and neuronal pathology in transgenic mice expressing the carboxylterminal fragment of the Alzheimer amyloid precursor in the brain, Proc. Natl. Acad. Sci. USA, 1992, 89: 1085.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1085
    • Kammessheidt, E.1    Boyce, F.2    Spanoyan, S.3
  • 12
    • 0025853053 scopus 로고
    • Alzheimer's mutation
    • Tanzi, R. E., Hyman, B. T., Alzheimer's mutation, Nature, 1991, 350: 564.
    • (1991) Nature , vol.350 , pp. 564
    • Tanzi, R.E.1    Hyman, B.T.2
  • 13
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutation in early-onset familial AD
    • Herrington, R., Rogaer, E. L., Liang D. et al., Cloning of a gene bearing missense mutation in early-onset familial AD, Nature, 1995, 375: 754.
    • (1995) Nature , vol.375 , pp. 754
    • Herrington, R.1    Rogaer, E.L.2    Liang, D.3
  • 14
    • 0029087026 scopus 로고
    • Candidate gene for the chromosome 1 fimilial AD locus
    • Levy-Lakad, E., Wasco, W., Poorkaj, P. et al., Candidate gene for the chromosome 1 fimilial AD locus, Science, 1995, 269: 973.
    • (1995) Science , vol.269 , pp. 973
    • Levy-Lakad, E.1    Wasco, W.2    Poorkaj, P.3
  • 15
    • 0026646605 scopus 로고
    • Isolation and quantification of soluble Alzheimer's b-peptide from biological fluids
    • Seubeit, P., Bigo-Pelfrey, C., Esch, F. et al., Isolation and quantification of soluble Alzheimer's b-peptide from biological fluids, Nature, 1992, 359: 325.
    • (1992) Nature , vol.359 , pp. 325
    • Seubeit, P.1    Bigo-Pelfrey, C.2    Esch, F.3
  • 16
    • 0029087026 scopus 로고
    • Candidate gene for the chromosome 1 familiar AD locus
    • Levy-Lakad, E., Wasco, W., Poorkaj, P. et al., Candidate gene for the chromosome 1 familiar AD locus, Science, 1995, 269: 973.
    • (1995) Science , vol.269 , pp. 973
    • Levy-Lakad, E.1    Wasco, W.2    Poorkaj, P.3
  • 17
    • 37049048544 scopus 로고
    • Paired helical filaments in electron microscopy of Alzheimer disease
    • Kidd, M., Paired helical filaments in electron microscopy of Alzheimer disease, Nature, 1963, 197: 192.
    • (1963) Nature , vol.197 , pp. 192
    • Kidd, M.1
  • 18
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer related change
    • Braak, H., Braak, E., Neuropathological staging of Alzheimer related change, Acta Neuropathol, 1991, 82: 239.
    • (1991) Acta Neuropathol , vol.82 , pp. 239
    • Braak, H.1    Braak, E.2
  • 19
    • 0024044195 scopus 로고
    • Cloning and sequencing of the cDNA encoding a core-protein of the paired helical filament of AD identification as the microtubule-associated protein Tau
    • Wischik, C. M., Novak, M., Thogersen, H. C. et al., Cloning and sequencing of the cDNA encoding a core-protein of the paired helical filament of AD identification as the microtubule-associated protein Tau, Proc. Natl. Acad. Sci. USA, 1988, 85: 4884.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4884
    • Wischik, C.M.1    Novak, M.2    Thogersen, H.C.3
  • 20
    • 85034546591 scopus 로고
    • Tumor promoter induces reorganization of actin in filaments and calstectin (fodrin or nonerythroid electron) in 3T3 cell
    • Geodert, M., Wischik, C. M., Growth, R. A. et al., Tumor promoter induces reorganization of actin in filaments and calstectin (fodrin or nonerythroid electron) in 3T3 cell, Proc. Natl. Acad. Sci. USA, 1988, 85: 4051.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4051
    • Geodert, M.1    Wischik, C.M.2    Growth, R.A.3
  • 21
    • 0024522781 scopus 로고
    • Two separate 18-amino acid domains of Tau promote the polymerization of tubulin
    • Ennulat, D. J., Lliem, R. K. H., Hahim, G. A. et al., Two separate 18-amino acid domains of Tau promote the polymerization of tubulin, J. Biol. Chem., 1989, 264: 5327.
    • (1989) J. Biol. Chem. , vol.264 , pp. 5327
    • Ennulat, D.J.1    Lliem, R.K.H.2    Hahim, G.A.3
  • 22
    • 0027420369 scopus 로고
    • Tau protein and the neurofibrillary pathology of AD
    • Goedert, M., Tau protein and the neurofibrillary pathology of AD, Trends Neurosci, 1993, 15: 460.
    • (1993) Trends Neurosci , vol.15 , pp. 460
    • Goedert, M.1
  • 23
    • 0027217679 scopus 로고
    • The abnormal phosphorylation of Tau protein at Ser-202 in AD recapitulates phosphorylation during development
    • Goedert, M., Jakes, R., Crowther, R. A. et al., The abnormal phosphorylation of Tau protein at Ser-202 in AD recapitulates phosphorylation during development, Proc. Natl. Acad. Sci. USA, 1993, 90: 5066.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5066
    • Goedert, M.1    Jakes, R.2    Crowther, R.A.3
  • 24
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of AD in late onset families
    • Corder, E. H., Saunders, A. M., Stvittamrter, W. J. et al., Gene dose of apolipoprotein E type 4 allele and the risk of AD in late onset families, Science, 1993, 261: 921.
    • (1993) Science , vol.261 , pp. 921
    • Corder, E.H.1    Saunders, A.M.2    Stvittamrter, W.J.3
  • 26
    • 0028232662 scopus 로고
    • Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro
    • Nathan, B. P., Bellosta, S., Sanan, D. A. et al., Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro, Science, 1994, 246: 850.
    • (1994) Science , vol.246 , pp. 850
    • Nathan, B.P.1    Bellosta, S.2    Sanan, D.A.3
  • 27
    • 0029614329 scopus 로고
    • + causes DNA fragment and increase the BCL-2 expression in human neuroblastoma through different mechanisms
    • + causes DNA fragment and increase the BCL-2 expression in human neuroblastoma through different mechanisms, Brain Res., 1995, 704: 240.
    • (1995) Brain Res. , vol.704 , pp. 240
    • Itano, D.1    Nomura, Y.2
  • 28
    • 0029087026 scopus 로고
    • Candidate gene for the chromosome 1 familial AD locus
    • Levy-Lahad, E., Wasco, W., Poorkaj, P. et al., Candidate gene for the chromosome 1 familial AD locus, Science, 1995, 269: 973.
    • (1995) Science , vol.269 , pp. 973
    • Levy-Lahad, E.1    Wasco, W.2    Poorkaj, P.3
  • 29
    • 0030856029 scopus 로고    scopus 로고
    • New lesion found in diseased brains
    • Wade, R., New lesion found in diseased brains, Science, 1997, 277: 31.
    • (1997) Science , vol.277 , pp. 31
    • Wade, R.1
  • 30
    • 0030851793 scopus 로고    scopus 로고
    • Prusiner recognized for once-heretical prion theory
    • Vogel, G., Prusiner recognized for once-heretical prion theory, Science, 1997, 278: 214.
    • (1997) Science , vol.278 , pp. 214
    • Vogel, G.1
  • 31
    • 0030820354 scopus 로고    scopus 로고
    • The same prion strain causes vCJD and BSE
    • Hill, A. F., Desbrulais, M., Joiner, S. et al., The same prion strain causes vCJD and BSE, Nature, 1997, 389: 448.
    • (1997) Nature , vol.389 , pp. 448
    • Hill, A.F.1    Desbrulais, M.2    Joiner, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.